Literature DB >> 31528693

A liquid biopsy assay for identifying early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals.

Chunfeng Qu1, Yuchen Jiao1, Yuting Wang2.   

Abstract

Biannual screening of hepatocellular carcinoma (HCC) by ultrasonography and serum α-fetoprotein has been proposed to the HBsAg-seropositive individuals. The widespread application to all of them was restricted due to limited acceptability of resource and anxiety-producing procedures. We recently developed a novel liquid biopsy assay to identify HCC cases in asymptomatic HBsAg-positive individuals.

Entities:  

Keywords:  Hepatocellular carcinoma; circulating tumor DNA; early detection; liquid biopsy

Year:  2019        PMID： 31528693      PMCID： PMC6736321          DOI： 10.1080/23723556.2019.1614419

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

Review 1.  Asia-Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update.

Authors:  Masao Omata; Ann-Lii Cheng; Norihiro Kokudo; Masatoshi Kudo; Jeong Min Lee; Jidong Jia; Ryosuke Tateishi; Kwang-Hyub Han; Yoghesh K Chawla; Shuichiro Shiina; Wasim Jafri; Diana Alcantara Payawal; Takamasa Ohki; Sadahisa Ogasawara; Pei-Jer Chen; Cosmas Rinaldi A Lesmana; Laurentius A Lesmana; Rino A Gani; Shuntaro Obi; A Kadir Dokmeci; Shiv Kumar Sarin
Journal:  Hepatol Int       Date:  2017-06-15       Impact factor: 6.047

2.  AASLD guidelines for the treatment of hepatocellular carcinoma.

Authors:  Julie K Heimbach; Laura M Kulik; Richard S Finn; Claude B Sirlin; Michael M Abecassis; Lewis R Roberts; Andrew X Zhu; M Hassan Murad; Jorge A Marrero
Journal:  Hepatology       Date:  2018-01       Impact factor: 17.425

3.  Evaluation of alpha-fetoprotein as a screening marker for hepatocellular carcinoma in hepatitis prevalent areas.

Authors:  Sejong Chun; Su Yeon Rhie; Chang-Seok Ki; Jee Eun Kim; Hyung-Doo Park
Journal:  Ann Hepatol       Date:  2015 Nov-Dec       Impact factor: 2.400

Review 4.  EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma.

Authors: 
Journal:  J Hepatol       Date:  2018-04-05       Impact factor: 25.083

5.  Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy.

Authors:  Chunfeng Qu; Yuting Wang; Pei Wang; Kun Chen; Minjie Wang; Hongmei Zeng; Jianquan Lu; Qianqian Song; Bill H Diplas; Da Tan; Chunsun Fan; Qigao Guo; Zheng Zhu; Huihui Yin; Liping Jiang; Xixi Chen; Hui Zhao; Huan He; Yong Wang; Guangyu Li; Xinyu Bi; Xinming Zhao; Taoyang Chen; Hongping Tang; Chuanguo Lv; Dongmei Wang; Wanqing Chen; Jianguo Zhou; Hong Zhao; Jianqiang Cai; Xiaoyue Wang; Sizhen Wang; Hai Yan; Yi-Xin Zeng; Webster K Cavenee; Yuchen Jiao
Journal:  Proc Natl Acad Sci U S A       Date:  2019-03-11       Impact factor: 11.205

6.  Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma.

Authors:  Rui-Hua Xu; Wei Wei; Michal Krawczyk; Wenqiu Wang; Huiyan Luo; Ken Flagg; Shaohua Yi; William Shi; Qingli Quan; Kang Li; Lianghong Zheng; Heng Zhang; Bennett A Caughey; Qi Zhao; Jiayi Hou; Runze Zhang; Yanxin Xu; Huimin Cai; Gen Li; Rui Hou; Zheng Zhong; Danni Lin; Xin Fu; Jie Zhu; Yaou Duan; Meixing Yu; Binwu Ying; Wengeng Zhang; Juan Wang; Edward Zhang; Charlotte Zhang; Oulan Li; Rongping Guo; Hannah Carter; Jian-Kang Zhu; Xiaoke Hao; Kang Zhang
Journal:  Nat Mater       Date:  2017-10-09       Impact factor: 43.841

Review 7.  Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.

Authors:  Jessica Zucman-Rossi; Augusto Villanueva; Jean-Charles Nault; Josep M Llovet
Journal:  Gastroenterology       Date:  2015-06-20       Impact factor: 22.682

8.  Randomized controlled trial of screening for hepatocellular carcinoma.

Authors:  Bo-Heng Zhang; Bing-Hui Yang; Zhao-You Tang
Journal:  J Cancer Res Clin Oncol       Date:  2004-07       Impact factor: 4.553

9.  Detection and localization of surgically resectable cancers with a multi-analyte blood test.

Authors:  Joshua D Cohen; Lu Li; Yuxuan Wang; Christopher Thoburn; Bahman Afsari; Ludmila Danilova; Christopher Douville; Ammar A Javed; Fay Wong; Austin Mattox; Ralph H Hruban; Christopher L Wolfgang; Michael G Goggins; Marco Dal Molin; Tian-Li Wang; Richard Roden; Alison P Klein; Janine Ptak; Lisa Dobbyn; Joy Schaefer; Natalie Silliman; Maria Popoli; Joshua T Vogelstein; James D Browne; Robert E Schoen; Randall E Brand; Jeanne Tie; Peter Gibbs; Hui-Li Wong; Aaron S Mansfield; Jin Jen; Samir M Hanash; Massimo Falconi; Peter J Allen; Shibin Zhou; Chetan Bettegowda; Luis A Diaz; Cristian Tomasetti; Kenneth W Kinzler; Bert Vogelstein; Anne Marie Lennon; Nickolas Papadopoulos
Journal:  Science       Date:  2018-01-18       Impact factor: 47.728

10.  Mass screening for liver cancer: results from a demonstration screening project in Zhongshan City, China.

Authors:  Mingfang Ji; Zhiwei Liu; Ellen T Chang; Xia Yu; Biaohua Wu; Li Deng; Qianjin Feng; Kuangrong Wei; Xuejun Liang; Shifeng Lian; Wen Quan; Panpan Wang; Yun Du; Zhiheng Liang; Shenglin Xia; Hai Lin; Fugui Li; Weimin Cheng; Weiqiang Chen; Yong Yuan; Weimin Ye
Journal:  Sci Rep       Date:  2018-08-24       Impact factor: 4.379
  10 in total

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