| Literature DB >> 31516267 |
Narendra S Choudhary1, Ajay Duseja2.
Abstract
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. Patients with NAFLD are at a higher risk of developing cardiovascular disease (CVD). In fact, CVD-related mortality is more common in patients with NAFLD in comparison to liver-related mortality. This association is related to the common metabolic risk factors such as obesity, dyslipidemia, diabetes, and hypertension shared by both NAFLD and CVD, and also there is independent association of NAFLD with CVD because of risk factors such as insulin resistance, systemic inflammation, and atherogenic dyslipidemia. While there is abundant literature on association of NAFLD with CVD, there is sparse literature regarding the screening for CVD in patients with NAFLD. In the current review article, we discuss as to which patients with NAFLD to screen and how to screen for CVD.Entities:
Keywords: BMI, Body Mass Index; CAD, Coronary Artery Disease; CI, Confidence Interval; CVD, Cardiovascular Disease; DM, Diabetes Mellitus; DSE, Dobutamine Stress ECHO; HDL, High-Density Lipoprotein; ILTS, International Liver Transplantation Society; LDL, Low-Density Lipoprotein; NAFL, Nonalcoholic Fatty Liver; NAFLD, Nonalcoholic Fatty Liver Disease; NASH, Nonalcoholic Steatohepatitis; OR, Odds Ratio; atherosclerosis; cirrhosis; hs-CRP, High-Sensitivity C-Reactive Protein; metabolic syndrome; risk scores; screening
Year: 2019 PMID： 31516267 PMCID： PMC6728527 DOI： 10.1016/j.jceh.2019.02.005
Source DB: PubMed Journal: J Clin Exp Hepatol ISSN： 0973-6883