| Literature DB >> 33746450 |
Narendra S Choudhary1, Neeraj Saraf1, Sanjiv Saigal1, Arvinder S Soin1.
Abstract
The survival of liver transplantation (LT) recipients has been improved remarkably in short-term. The major causes of mortality in long-term include nonimmunological causes such as cardiovascular, de novo malignancy, chronic kidney disease, and recurrence of primary disease. Rejection-related mortality is rare in the long-term after LT. We discuss nonrejection causes of long-term morbidity/mortality, risk factors, and management strategies in LT recipients. In addition, we discuss osteoporosis, contraception, and pregnancy in LT recipients.Entities:
Keywords: AIH, autoimmune hepatitis; BMI, body mass index; CKD, chronic kidney disease; CNI, calcineurin inhibitors; CVD, cardiovascular disease; DDLT, deceased donor liver transplantation; DM, diabetes mellitus; DNM, de novo malignancy; HCV, hepatitis C virus; HR, hazard ratio; IUCD, Intrauterine contraceptive devices; LDLT, living donor liver transplantation; LT, liver transplantation; MDRD, Modification of Diet in Renal Disease; MMF, mycophenolate; MS, metabolic syndrome; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; OR, odds ratio; PBC, primary biliary cholangitis; PSC, primary sclerosing cholangitis; PTDM, posttransplantation diabetes mellitus; PTMS, posttransplantation metabolic syndrome; SVR, sustained virological response; cardiovascular disease; de novo malignancy; eGFR, estimated glomerular filtration rate; mTORi, Mammalian target of rapamycin inhibitors; osteoporosis; pregnancy; recurrence
Year: 2020 PMID： 33746450 PMCID： PMC7953009 DOI： 10.1016/j.jceh.2020.06.010
Source DB: PubMed Journal: J Clin Exp Hepatol ISSN： 0973-6883