Literature DB >> 31512611

Multidrug resistance as a cause of steroid-nonresponsive downgrading type I reaction in Hansen's disease.

Surabhi Sinha1, Kabir Sardana1, Diksha Agrawal1, Purnima Malhotra2, Mallika Lavania3, Madhvi Ahuja3.   

Abstract

While Type 1 reaction in Hansen's disease is commonly encountered, the triggers and reasons for its persistence are not well understood even though the immunological milieu and cytokine interplay have been studied. Herein, we present a case of Type 1 downgrading reaction in which multidrug resistance was the probable cause of steroid-nonresponsiveness and which responded promptly on starting alternate antileprosy treatment.

Entities:  

Keywords:  Downgrading reaction; leprosy; resistance; type 1 reaction

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Year:  2019        PMID: 31512611     DOI: 10.4103/ijmy.ijmy_121_19

Source DB:  PubMed          Journal:  Int J Mycobacteriol        ISSN: 2212-5531


  3 in total

1.  Case Report: Chemoradiation with Paclitaxel and Carboplatin Unveiling Leprosy Type 1 Downgrading Reaction.

Authors:  B Savitha; Kabir Sardana; Ananta Khurana; Seema Rani; Soumya Sachdeva; Arvind Ahuja
Journal:  Am J Trop Med Hyg       Date:  2022-06-06       Impact factor: 3.707

2.  Case Report: Multidrug-Resistant Mycobacterium leprae in a Case of Smear-Negative Relapse.

Authors:  Divya Kamat; Tarun Narang; Madhvi Ahuja; Mallika Lavania; Sunil Dogra
Journal:  Am J Trop Med Hyg       Date:  2020-04       Impact factor: 2.345

3.  Leprosy stigma & the relevance of emergent therapeutic options.

Authors:  Kabir Sardana; Ananta Khurana
Journal:  Indian J Med Res       Date:  2020-01       Impact factor: 2.375

  3 in total

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