Literature DB >> 31508873

Why are we still using opioids for osteoarthritis?

Kevin Yip1, Jason Oettinger2.   

Abstract

Osteoarthritis is a common debilitating condition affecting a substantial portion of the population and is an accepted consequence of ageing and overuse. Whilst surgical interventions are a definitive approach, most cases are managed medically with analgesia. Pharmacological therapies have included acetaminophen, non-steroidal anti-inflammatory drugs and opiates. Although significant controversies exist in the use of opioids for chronic musculoskeletal pain, many leading guidelines continue to recommend its use despite increasing evidence to suggest an increase in addiction, morbidity and mortality. With the opiate crisis growing, we re-examine the role opiates have in this chronic condition and current data, and briefly evaluate alternative therapies.
© 2019 John Wiley & Sons Ltd.

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Year:  2019        PMID: 31508873     DOI: 10.1111/ijcp.13416

Source DB:  PubMed          Journal:  Int J Clin Pract        ISSN: 1368-5031            Impact factor:   2.503


  4 in total

Review 1.  Therapeutic Agents for the Treatment of Temporomandibular Joint Disorders: Progress and Perspective.

Authors:  Mengjie Wu; Jingyi Cai; Yeke Yu; Sihui Hu; Yingnan Wang; Mengrui Wu
Journal:  Front Pharmacol       Date:  2021-01-29       Impact factor: 5.810

2.  Medical Cannabis Use Reduces Opioid Prescriptions in Patients With Osteoarthritis.

Authors:  Bryan Renslo; Ari Greis; Conan S Liu; Anjithaa Radakrishnan; Asif M Ilyas
Journal:  Cureus       Date:  2022-01-24

3.  Astilbin prevents osteoarthritis development through the TLR4/MD-2 pathway.

Authors:  Shuaibo Sun; Zijian Yan; Xiaolong Shui; Weihui Qi; Yanlin Chen; Xinxian Xu; Yuezheng Hu; Weijun Guo; Ping Shang
Journal:  J Cell Mol Med       Date:  2020-10-16       Impact factor: 5.295

4.  Sick Leave and Costs in Active Workers with Chronic Osteoarthritis Pain in Spain: Outcomes of the OPIOIDS Real World Study.

Authors:  Antoni Sicras-Mainar; Juan Carlos Tornero-Tornero; Francisco Vargas-Negrín; Isabel Lizarraga; Aram Sicras-Navarro; Javier Rejas-Gutierrez
Journal:  Open Access Rheumatol       Date:  2022-03-15
  4 in total

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