Literature DB >> 33584275

Therapeutic Agents for the Treatment of Temporomandibular Joint Disorders: Progress and Perspective.

Mengjie Wu1, Jingyi Cai2, Yeke Yu3, Sihui Hu1, Yingnan Wang1, Mengrui Wu4.   

Abstract

Temporomandibular joint disorders (TMD) are a common health condition caused by the structural or functional disorders of masticatory muscles and the temporomandibular joint (TMJ). Abnormal mandibular movement in TMD patients may cause pain, chronic inflammation, and other discomfort, which could be relieved by a variety of drugs through various delivery systems. In this study, we summarized commonly used therapeutic agents in the management of TMD as well as novel bioactive molecules in preclinical stage and clinical trials. The emerging therapy strategies such as novel intra-TMJ delivery systems and implants based on tissue engineering are also discussed. This comprehensive review will strengthen our understanding of pharmacological approaches for TMD therapy.
Copyright © 2021 Wu, Cai, Yu, Hu, Wang and Wu.

Entities:  

Keywords:  intra-TMJ injection; mandibular dysfunction; pain management; temporomandibular joint; temporomandibular joint disorder

Year:  2021        PMID： 33584275      PMCID： PMC7878564          DOI： 10.3389/fphar.2020.596099

Source DB:  PubMed          Journal:  Front Pharmacol        ISSN： 1663-9812            Impact factor:   5.810


  110 in total

1.  Sulfated polysaccharide from the green marine algae Caulerpa racemosa reduces experimental pain in the rat temporomandibular joint.

Authors:  Natássia Albuquerque Ribeiro; Hellíada Vasconcelos Chaves; Renata Line da Conceição Rivanor; Danielle Rocha do Val; Ellen Lima de Assis; Felipe Dantas Silveira; Francisco Isaac Fernandes Gomes; Hermany Capistrano Freitas; Lorena Vasconcelos Vieira; Deiziane Viana da Silva Costa; Gerly Anne de Castro Brito; Mirna Marques Bezerra; Norma Maria Barros Benevides
Journal:  Int J Biol Macromol       Date:  2020-01-28       Impact factor: 6.953

2.  Magnesium in Pain Research: State of the Art.

Authors:  Dragana Srebro; Sonja Vuckovic; Aleksandar Milovanovic; Jovan Kosutic; Katarina Savic Vujovic; Milica Prostran
Journal:  Curr Med Chem       Date:  2017       Impact factor: 4.530

Review 3.  Tissue Engineering for the Temporomandibular Joint.

Authors:  Timothy M Acri; Kyungsup Shin; Dongrim Seol; Noah Z Laird; Ino Song; Sean M Geary; Jaidev L Chakka; James A Martin; Aliasger K Salem
Journal:  Adv Healthc Mater       Date:  2018-12-17       Impact factor: 9.933

Review 4.  Osteochondral alterations in osteoarthritis.

Authors:  Sunita Suri; David A Walsh
Journal:  Bone       Date:  2011-10-17       Impact factor: 4.398

5.  Clinical efficacy of new α-bisabolol mouthwashes in postoperative complications of maxillofacial surgeries: a randomized, controlled, triple-blind clinical trial.

Authors:  Bruno Frota Amora-Silva; S C Ribeiro; C L Vieira; F R Mendes; A E Vieira-Neto; A P V Abdon; F N Costa; A R Campos
Journal:  Clin Oral Investig       Date:  2018-05-03       Impact factor: 3.573

6.  Changes in temporomandibular pain and other symptoms across the menstrual cycle.

Authors:  Linda LeResche; Lloyd Mancl; Jeffrey J Sherman; Beatrice Gandara; Samuel F Dworkin
Journal:  Pain       Date:  2003-12       Impact factor: 6.961

Review 7.  Pharmacologic management of temporomandibular disorders.

Authors:  Elliot V Hersh; Ramesh Balasubramaniam; Andres Pinto
Journal:  Oral Maxillofac Surg Clin North Am       Date:  2008-05       Impact factor: 2.802

Review 8.  Efficacies of different preparations of glucosamine for the treatment of osteoarthritis: a meta-analysis of randomised, double-blind, placebo-controlled trials.

Authors:  D Wu; Y Huang; Y Gu; W Fan
Journal:  Int J Clin Pract       Date:  2013-06       Impact factor: 2.503

Review 9.  Interventions for the management of temporomandibular joint osteoarthritis.

Authors:  Raphael Freitas de Souza; Claudia H Lovato da Silva; Mona Nasser; Zbys Fedorowicz; Mohammed A Al-Muharraqi
Journal:  Cochrane Database Syst Rev       Date:  2012-04-18

10.  Resveratrol alleviates temporomandibular joint inflammatory pain by recovering disturbed gut microbiota.

Authors:  Yajing Ma; Sufang Liu; Hui Shu; Joshua Crawford; Ying Xing; Feng Tao
Journal:  Brain Behav Immun       Date:  2020-01-27       Impact factor: 19.227
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  1 in total

1.  BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin-YAP Signaling Axis.

Authors:  Yingnan Wang; Miaomiao Zhao; Wen Li; Yuzhi Yang; Zhenliang Zhang; Ruijie Ma; Mengjie Wu
Journal:  Front Cell Dev Biol       Date:  2021-04-01
  1 in total

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