Literature DB >> 31495572

An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers.

Vasant Shinde1, Vagheesh M Narasimhan2, Nadin Rohland3, Swapan Mallick4, Matthew Mah4, Mark Lipson3, Nathan Nakatsuka3, Nicole Adamski5, Nasreen Broomandkhoshbacht5, Matthew Ferry5, Ann Marie Lawson5, Megan Michel5, Jonas Oppenheimer5, Kristin Stewardson5, Nilesh Jadhav6, Yong Jun Kim6, Malavika Chatterjee6, Avradeep Munshi6, Amrithavalli Panyam6, Pranjali Waghmare6, Yogesh Yadav6, Himani Patel7, Amit Kaushik8, Kumarasamy Thangaraj9, Matthias Meyer10, Nick Patterson11, Niraj Rai12, David Reich13.   

Abstract

We report an ancient genome from the Indus Valley Civilization (IVC). The individual we sequenced fits as a mixture of people related to ancient Iranians (the largest component) and Southeast Asian hunter-gatherers, a unique profile that matches ancient DNA from 11 genetic outliers from sites in Iran and Turkmenistan in cultural communication with the IVC. These individuals had little if any Steppe pastoralist-derived ancestry, showing that it was not ubiquitous in northwest South Asia during the IVC as it is today. The Iranian-related ancestry in the IVC derives from a lineage leading to early Iranian farmers, herders, and hunter-gatherers before their ancestors separated, contradicting the hypothesis that the shared ancestry between early Iranians and South Asians reflects a large-scale spread of western Iranian farmers east. Instead, sampled ancient genomes from the Iranian plateau and IVC descend from different groups of hunter-gatherers who began farming without being connected by substantial movement of people.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Harappan Civilization; Indus Valley Civilization; South Asia; ancient DNA; anthropology; archaeology; population genetics

Mesh:

Substances:

Year:  2019        PMID: 31495572      PMCID: PMC6800651          DOI: 10.1016/j.cell.2019.08.048

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


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