Literature DB >> 31489460

Varus alignment increases medial meniscus extrusion and peak contact pressure: a biomechanical study.

Lukas Willinger1, Jan J Lang2,3,4, Constantin von Deimling2,5, Theresa Diermeier1, Wolf Petersen6, Andreas B Imhoff7, Rainer Burgkart2, Andrea Achtnich1.   

Abstract

PURPOSE: Assessment of medial meniscus extrusion (MME) has become increasingly popular in clinical practice to evaluate the dynamic meniscus function and diagnose meniscus pathologies. The purpose of this biomechanical study was to investigate the correlation between MME and the changes in joint contact pressure in varus and valgus alignment. It was hypothesized that varus alignment would result in significantly higher MME along with a higher joint contact pressure in the medial compartment.
METHODS: Eight fresh-frozen human cadaveric knees were axially loaded, with a 750 N compressive load, in full extension with the mechanical axis shifted to intersect the tibial plateau at 30% and 40% (varus), 50% (neutral), 60% and 70% (valgus) of its width (TPW). Tibiofemoral peak contact pressure (PCP), mean contact pressure (MCP) and contact area (CA) were determined using pressure-sensitive films. MME was obtained via ultrasound at maximum load.
RESULTS: MME was significantly increased from valgus (1.32 ± 0.22 mm) to varus alignment (3.16 ± 0.24 mm; p < 0.001). Peak contact pressure at 30% TPW varus alignment was significantly higher compared to 60% TPW valgus (p = 0.018) and 70% TPW valgus (p < 0.01). MME significantly correlated with PCP (r = 0.56; p < 0.001) and MCP (r = 0.47, p < 0.01) but not with CA (r = 0.23; n.s.).
CONCLUSION: MME was significantly increased in varus alignment, compared to neutral or valgus alignment, with an intact medial meniscus. It was also significantly correlated with PCP and MCP within the medial compartment. However, valgus malalignment and neutral axis resulted in reduced MME and contact pressure. Lower limb alignment must be taken into account while assessing MME in clinical practice. LEVEL OF EVIDENCE: Controlled laboratory study.

Entities:  

Keywords:  Contact pressure; Lower limb alignment; Medial meniscus extrusion; Ultrasound; Valgus; Varus

Mesh:

Year:  2019        PMID: 31489460     DOI: 10.1007/s00167-019-05701-1

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  32 in total

1.  The role of knee alignment in disease progression and functional decline in knee osteoarthritis.

Authors:  L Sharma; J Song; D T Felson; S Cahue; E Shamiyeh; D D Dunlop
Journal:  JAMA       Date:  2001-07-11       Impact factor: 56.272

2.  Ultrasound assessment of medial meniscal extrusion: a validation study using MRI as reference standard.

Authors:  Marcello H Nogueira-Barbosa; Everaldo Gregio-Junior; Mario M Lorenzato; Ali Guermazi; Frank W Roemer; Francisco A Chagas-Neto; Michel D Crema
Journal:  AJR Am J Roentgenol       Date:  2015-03       Impact factor: 3.959

3.  No dynamic extrusion of the medial meniscus in ultrasound examination in patients with confirmed root tear lesion.

Authors:  Katrin Karpinski; Theresa Diermeier; Lukas Willinger; Andreas B Imhoff; Andrea Achtnich; Wolf Petersen
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2019-01-03       Impact factor: 4.342

4.  Load-bearing in the knee joint.

Authors:  N G Shrive; J J O'Connor; J W Goodfellow
Journal:  Clin Orthop Relat Res       Date:  1978 Mar-Apr       Impact factor: 4.176

5.  Meniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees.

Authors:  Yuanyuan Wang; Anita E Wluka; Jean-Pierre Pelletier; Johanne Martel-Pelletier; François Abram; Changhai Ding; Flavia M Cicuttini
Journal:  Rheumatology (Oxford)       Date:  2010-02-24       Impact factor: 7.580

6.  The role of meniscal root pathology and radial meniscal tear in medial meniscal extrusion.

Authors:  D B Lerer; H R Umans; M X Hu; M H Jones
Journal:  Skeletal Radiol       Date:  2004-08-14       Impact factor: 2.199

7.  Medial meniscus extrusion on knee MRI: is extent associated with severity of degeneration or type of tear?

Authors:  C Rosalia Costa; William B Morrison; John A Carrino
Journal:  AJR Am J Roentgenol       Date:  2004-07       Impact factor: 3.959

8.  Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees.

Authors:  Leena Sharma; Felix Eckstein; Jing Song; Ali Guermazi; Pottumarthi Prasad; Dipali Kapoor; September Cahue; Meredith Marshall; Martin Hudelmaier; Dorothy Dunlop
Journal:  Arthritis Rheum       Date:  2008-06

9.  Long term evaluation of disease progression through the quantitative magnetic resonance imaging of symptomatic knee osteoarthritis patients: correlation with clinical symptoms and radiographic changes.

Authors:  Jean-Pierre Raynauld; Johanne Martel-Pelletier; Marie-Josée Berthiaume; Gilles Beaudoin; Denis Choquette; Boulos Haraoui; Hyman Tannenbaum; Joan M Meyer; John F Beary; Gary A Cline; Jean-Pierre Pelletier
Journal:  Arthritis Res Ther       Date:  2005-12-30       Impact factor: 5.156

10.  Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume.

Authors:  Changhai Ding; Johanne Martel-Pelletier; Jean-Pierre Pelletier; François Abram; Jean-Pierre Raynauld; Flavia Cicuttini; Graeme Jones
Journal:  Arthritis Res Ther       Date:  2007       Impact factor: 5.156

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  10 in total

1.  Short-term results and surgical technique of arthroscopic centralization as an augmentation for medial meniscus extrusion caused by medial meniscus posterior root tear.

Authors:  Yuta Mochizuki; Keisuke Kawahara; Yuji Samejima; Takao Kaneko; Hiroyasu Ikegami; Yoshiro Musha
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-01-21

2.  High-grade preoperative osteoarthritis of the index compartment is a major predictor of meniscal allograft failure.

Authors:  Philipp W Winkler; Nyaluma N Wagala; Jonathan D Hughes; Volker Musahl
Journal:  Arch Orthop Trauma Surg       Date:  2022-01-05       Impact factor: 3.067

Review 3.  Effects of and Response to Mechanical Loading on the Knee.

Authors:  David S Logerstedt; Jay R Ebert; Toran D MacLeod; Bryan C Heiderscheit; Tim J Gabbett; Brian J Eckenrode
Journal:  Sports Med       Date:  2021-10-20       Impact factor: 11.136

4.  Treatment of Malalignment and Cartilage Injury: High Tibial Osteotomy With a Concomitant Osteochondral Allograft to the Medial Femoral Condyle and Lateral and Medial Partial Meniscectomy.

Authors:  Toufic R Jildeh; Spencer M Comfort; Annalise M Peebles; Sarah N Powell; Matthew T Provencher
Journal:  Arthrosc Tech       Date:  2022-03-19

Review 5.  Meniscal substitution, a developing and long-awaited demand.

Authors:  Philipp W Winkler; Benjamin B Rothrauff; Rafael A Buerba; Neha Shah; Stefano Zaffagnini; Peter Alexander; Volker Musahl
Journal:  J Exp Orthop       Date:  2020-07-25

Review 6.  [The influence of axial deformities and their correction on the development and progression of osteoarthritis].

Authors:  Florian B Imhoff; Sandro F Fucentese; Jörg Harrer; Thomas Tischer
Journal:  Orthopade       Date:  2021-04-12       Impact factor: 1.087

Review 7.  Meniscal Extrusion: A Narrative Review.

Authors:  Shreyash M Gajjar; Ketansinh P Solanki; Saseendar Shanmugasundaram; Srinivas B S Kambhampati
Journal:  Orthop J Sports Med       Date:  2021-11-03

8.  Large medial meniscus extrusion and varus are poor prognostic factors of arthroscopic partial meniscectomy for degenerative medial meniscus lesions.

Authors:  Tao Xu; Liuhai Xu; Xinzhi Li; You Zhou
Journal:  J Orthop Surg Res       Date:  2022-03-18       Impact factor: 2.359

9.  High Tibial Osteotomy for Varus Deformity of the Knee.

Authors:  Ryan Murray; Philipp W Winkler; Humza S Shaikh; Volker Musahl
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2021-07-09

10.  Sonographic evaluation of lateral meniscal extrusion: implementation and validation.

Authors:  Philipp W Winkler; Robert Csapo; Guido Wierer; Caroline Hepperger; Bernhard Heinzle; Andreas B Imhoff; Christian Hoser; Christian Fink
Journal:  Arch Orthop Trauma Surg       Date:  2020-11-20       Impact factor: 3.067

  10 in total

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