Gabriela M Espinoza1, Jessica L Liu2. 1. Department of Ophthalmology, Saint Louis University School of Medicine, 1755 South Grand Blvd, Saint Louis, MO, 63104, USA. gabriela.espinoza@health.slu.edu. 2. Department of Ophthalmology, Saint Louis University School of Medicine, 1755 South Grand Blvd, Saint Louis, MO, 63104, USA.
Abstract
PURPOSE OF REVIEW: The orbit is subject to a variety of vascular insults that manifest with both specific and nonspecific patterns of vision compromise. The aim of the following review is to highlight the ophthalmic clinical features of systemic vasculitides that most frequently involve the orbit and differentiate them from the most common non-vasculitic orbital disorders. RECENT FINDINGS: New studies continue to explore the autoimmune nature of vasculitic disease and seek to determine optimal use of newer therapies such as biologic agents. The pattern of ocular involvement in the context of clinical history allows the knowledgeable physician to distill a differential diagnosis into a specific or likely cause. Establishing a diagnosis in a timely fashion allows for a custom-tailored approach to therapy.
PURPOSE OF REVIEW: The orbit is subject to a variety of vascular insults that manifest with both specific and nonspecific patterns of vision compromise. The aim of the following review is to highlight the ophthalmic clinical features of systemic vasculitides that most frequently involve the orbit and differentiate them from the most common non-vasculitic orbital disorders. RECENT FINDINGS: New studies continue to explore the autoimmune nature of vasculitic disease and seek to determine optimal use of newer therapies such as biologic agents. The pattern of ocular involvement in the context of clinical history allows the knowledgeable physician to distill a differential diagnosis into a specific or likely cause. Establishing a diagnosis in a timely fashion allows for a custom-tailored approach to therapy.
Authors: F Davatchi; F Shahram; H Chams; A R Jamshidi; A Nadji; C Chams; M Akbarian; F Gharibdoost Journal: Adv Exp Med Biol Date: 2003 Impact factor: 2.622
Authors: Gary S Hoffman; Maria C Cid; David B Hellmann; Loic Guillevin; John H Stone; John Schousboe; Pascal Cohen; Leonard H Calabrese; Howard Dickler; Peter A Merkel; Paul Fortin; John A Flynn; Geri A Locker; Kirk A Easley; Eric Schned; Gene G Hunder; Michael C Sneller; Carol Tuggle; Howard Swanson; J Hernández-Rodríguez; Alfons Lopez-Soto; Debora Bork; Diane B Hoffman; Kenneth Kalunian; David Klashman; William S Wilke; Raymond J Scheetz; Brian F Mandell; Barri J Fessler; Gregory Kosmorsky; Richard Prayson; Raashid A Luqmani; George Nuki; Euan McRorie; Yvonne Sherrer; Shawn Baca; Bridgit Walsh; Diane Ferland; Martin Soubrier; Hyon K Choi; Wolfgang Gross; Allen M Segal; Charles Ludivico; Xavier Puechal Journal: Arthritis Rheum Date: 2002-05