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Literature DB >> 31483230

The Therapeutic Potential of miR-7 in Cancers.

Miao Li¹, Meng Pan^1,2, Chengzhong You³, Jun Dou¹.

Abstract

MiRNAs play an important role in cancers. As a potent tumor suppressor, miRNA-7(miR-7) has been demonstrated to inhibit the diverse fundamental biological processes in multiple cancer types including initiation, growth and metastasis by targeting a number of molecules and signaling pathways. This current review summarizes and discusses the relationship between miR-7 and cancers and the therapeutic potential of miR-7 in cancers. It may provide new integrative understanding for future study on the role of miR-7 in cancers. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities: Disease Gene

Keywords: RISC; cancer cell signaling; ceRNA; miR-7; therapy; tumors.

Mesh：

Substances：

Year: 2019 PMID： 31483230 DOI： 10.2174/1389557519666190904141922

Source DB: PubMed Journal: Mini Rev Med Chem ISSN： 1389-5575 Impact factor: 3.862

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Cited

6 in total

1. Curcumol enhances cisplatin sensitivity of gastric cancer: involvement of microRNA-7 and the nuclear factor-kappa B/snail family transcriptional repressor 1 axis.

Authors: Ying Hu; Ruitong Xu; Jinxia Ma; Zhanpeng Yan; Jun Ma
Journal: Bioengineered Date: 2022-05 Impact factor: 6.832

2. Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.

Authors: Weisheng Guo; Lin Zhao; Guangya Wei; Peng Liu; Yu Zhang; Liran Fu
Journal: Cancer Manag Res Date: 2020-08-14 Impact factor: 3.989

6. Downregulation of lncRNA ANRIL Inhibits Osteogenic Differentiation of Periodontal Ligament Cells via Sponging miR-7 through NF-κB Pathway.

Authors: Xinwei Liu; Yue Zhou
Journal: Anal Cell Pathol (Amst) Date: 2021-11-24 Impact factor: 2.916

6 in total

The Therapeutic Potential of miR-7 in Cancers.

1. Curcumol enhances cisplatin sensitivity of gastric cancer: involvement of microRNA-7 and the nuclear factor-kappa B/snail family transcriptional repressor 1 axis.

2. Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.

3. Prognostic Value of miR-1826 in Prostate Cancer and Its Regulatory Effect on Tumor Progression.

4. Transcriptional Suppression of miR-7 by MTA2 Induces Sp1-Mediated KLK10 Expression and Metastasis of Cervical Cancer.

Review 5. Cascades between miRNAs, lncRNAs and the NF-κB signaling pathway in gastric cancer (Review).

6. Downregulation of lncRNA ANRIL Inhibits Osteogenic Differentiation of Periodontal Ligament Cells via Sponging miR-7 through NF-κB Pathway.