Literature DB >> 31479321

Identifying and Validating New Drug Targets for Stroke and Beyond: Can Mendelian Randomization Help?

Andrew Plump1, George Davey Smith2.   

Abstract

Entities:  

Keywords:  Editorials; Mendelian randomization analysis; drug discovery; stroke

Mesh：

Substances：

Year:  2019        PMID： 31479321     DOI： 10.1161/CIRCULATIONAHA.119.042005

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  4 in total

Review 1.  Genetics meets proteomics: perspectives for large population-based studies.

Authors:  Karsten Suhre; Mark I McCarthy; Jochen M Schwenk
Journal:  Nat Rev Genet       Date:  2020-08-28       Impact factor: 53.242

Review 2.  Genetics, Genomics, and Precision Medicine.

Authors:  James F Meschia; Martin Dichgans
Journal:  Stroke       Date:  2021-09-02       Impact factor: 10.170

3.  Mendelian randomisation with coarsened exposures.

Authors:  Matthew J Tudball; Jack Bowden; Rachael A Hughes; Amanda Ly; Marcus R Munafò; Kate Tilling; Qingyuan Zhao; George Davey Smith
Journal:  Genet Epidemiol       Date:  2021-02-01       Impact factor: 2.344

4.  Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.

Authors:  Lingyan Chen; James E Peters; Bram Prins; Elodie Persyn; Matthew Traylor; Praveen Surendran; Savita Karthikeyan; Ekaterina Yonova-Doing; Emanuele Di Angelantonio; David J Roberts; Nicholas A Watkins; Willem H Ouwehand; John Danesh; Cathryn M Lewis; Paola G Bronson; Hugh S Markus; Stephen Burgess; Adam S Butterworth; Joanna M M Howson
Journal:  Nat Commun       Date:  2022-10-17       Impact factor: 17.694
  4 in total

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