Literature DB >> 3145861

Emergence of bacterial resistance to cefamandole in vivo due to outer membrane protein deficiency.

J A van de Klundert1, M H van Gestel, G Meerdink, S de Marie.   

Abstract

Cefamandole therapy in a patient with suppurative thrombophlebitis failed due to selection of a resistant variant of the causative organism Klebsiella pneumoniae. Analysis of the resistance mechanism revealed that in the resistant variant one of the major outer membrane proteins, OmpF, was missing. Resistance of this type has implications for therapy with other antibiotics including non-beta-lactam antibiotics. This report demonstrates the role of outer membrane permeation in the emergence of bacterial resistance during antibiotic therapy.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3145861     DOI： 10.1007/bf01975046

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  9 in total

1.  Electrophoretic resolution of the "major outer membrane protein" of Escherichia coli K12 into four bands.

Authors:  B Lugtenberg; J Meijers; R Peters; P van der Hoek; L van Alphen
Journal:  FEBS Lett       Date:  1975-10-15       Impact factor: 4.124

Review 2.  Microbial resistance to newer generation beta-lactam antibiotics: clinical and laboratory implications.

Authors:  C C Sanders; W E Sanders
Journal:  J Infect Dis       Date:  1985-03       Impact factor: 5.226

Review 3.  Molecular epidemiology of bacterial infections: examples of methodology and of investigations of outbreaks.

Authors:  K Wachsmuth
Journal:  Rev Infect Dis       Date:  1986 Sep-Oct

Review 4.  The beta-lactamases of gram-negative bacteria and their possible physiological role.

Authors:  M H Richmond; R B Sykes
Journal:  Adv Microb Physiol       Date:  1973       Impact factor: 3.517

5.  Disc diffusion test for the determination of semi-quantitative substrate profiles of beta-lactamases.

Authors:  J A van de Klundert; M H van Gestel; E van Doorn; R P Mouton
Journal:  J Antimicrob Chemother       Date:  1986-04       Impact factor: 5.790

6.  Quinolone/ureidopenicillin cross-resistance.

Authors:  L J Piddock; W J Wijnands; R Wise
Journal:  Lancet       Date:  1987-10-17       Impact factor: 79.321

7.  Mutants of Escherichia coli that are resistant to certain beta-lactam compounds lack the ompF porin.

Authors:  K J Harder; H Nikaido; M Matsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1981-10       Impact factor: 5.191

8.  Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes.

Authors:  C C Sanders; W E Sanders; R V Goering; V Werner
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

9.  Resistance to cefamandole: a collaborative study of emerging clinical problems.

Authors:  C C Sanders; R C Moellering; R R Martin; R L Perkins; D G Strike; T D Gootz; W E Sanders
Journal:  J Infect Dis       Date:  1982-01       Impact factor: 5.226
  9 in total
  11 in total

1.  Difficult-to-treat infections.

Authors:  S de Marie
Journal:  Intensive Care Med       Date:  1990       Impact factor: 17.440

2.  MiniUIB, a novel minitransposon-based system for stable insertion of foreign DNA into the genomes of Gram-negative and Gram-positive bacteria.

Authors:  Joseph Alexander Christie-Oleza; Isabel Brunet-Galmés; Jorge Lalucat; Balbina Nogales; Rafael Bosch
Journal:  Appl Environ Microbiol       Date:  2012-12-28       Impact factor: 4.792

3.  Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.

Authors:  P A Bradford; C Urban; N Mariano; S J Projan; J J Rahal; K Bush
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

4.  Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes.

Authors:  S Hernández-Allés; V J Benedí; L Martínez-Martínez; A Pascual; A Aguilar; J M Tomás; S Albertí
Journal:  Antimicrob Agents Chemother       Date:  1999-04       Impact factor: 5.191

5.  Involvement of a 43-kilodalton outer membrane protein in beta-lactam resistance of Shigella dysenteriae.

Authors:  A K Kar; A S Ghosh; K Chauhan; J Ahamed; J Basu; P Chakrabarti; M Kundu
Journal:  Antimicrob Agents Chemother       Date:  1997-10       Impact factor: 5.191

6.  In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins.

Authors:  L Martínez-Martínez; S Hernández-Allés; S Albertí; J M Tomás; V J Benedi; G A Jacoby
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

Review 7.  Selective decontamination in bone marrow transplant recipients.

Authors:  H F Guiot; R van Furth
Journal:  Epidemiol Infect       Date:  1992-12       Impact factor: 2.451

8.  Outer membrane profiles of clonally related Klebsiella pneumoniae isolates from clinical samples and activities of cephalosporins and carbapenems.

Authors:  C Ardanuy; J Liñares; M A Domínguez; S Hernández-Allés; V J Benedí; L Martínez-Martínez
Journal:  Antimicrob Agents Chemother       Date:  1998-07       Impact factor: 5.191

9.  A porin from Klebsiella pneumoniae: sequence homology, three-dimensional model, and complement binding.

Authors:  S Albertí; F Rodríquez-Quiñones; T Schirmer; G Rummel; J M Tomás; J P Rosenbusch; V J Benedí
Journal:  Infect Immun       Date:  1995-03       Impact factor: 3.441

Review 10.  Targeting the Sugary Armor of Klebsiella Species.

Authors:  L Ponoop Prasad Patro; Thenmalarchelvi Rathinavelan
Journal:  Front Cell Infect Microbiol       Date:  2019-11-08       Impact factor: 5.293
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.