Literature DB >> 3143305

In vitro susceptibilities of Mycobacterium tuberculosis to 10 antimicrobial agents.

S K Byrne1, C E Crawford, G L Geddes, W A Black.   

Abstract

After preliminary in vitro screening of 10 antimicrobial agents against Mycobacterium tuberculosis, the MICs of the 6 most promising agents against 27 clinical isolates were determined by agar dilution. The two quinolone compounds tested (difloxacin and A-56620) were the most active, each inhibiting 50% of the strains at concentrations of 4 micrograms/ml. M. tuberculosis strains previously shown to be resistant to isoniazid, streptomycin, rifampin, or ethambutol were as susceptible to these quinolone compounds as susceptible strains.

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Year:  1988        PMID： 3143305      PMCID： PMC175887          DOI： 10.1128/AAC.32.9.1441

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  In vitro activities of norfloxacin and ciprofloxacin against Mycobacterium tuberculosis, M. avium complex, M. chelonei, M. fortuitum, and M. kansasii.

Authors:  J D Gay; D R DeYoung; G D Roberts
Journal:  Antimicrob Agents Chemother       Date:  1984-07       Impact factor: 5.191

2.  Difloxacin metabolism and pharmacokinetics in humans after single oral doses.

Authors:  G R Granneman; K M Snyder; V S Shu
Journal:  Antimicrob Agents Chemother       Date:  1986-11       Impact factor: 5.191

3.  Determination of in vitro susceptibility of Mycobacterium tuberculosis to cephalosporins by radiometric and conventional methods.

Authors:  L B Heifets; M D Iseman; J L Cook; P J Lindholm-Levy; I Drupa
Journal:  Antimicrob Agents Chemother       Date:  1985-01       Impact factor: 5.191

4.  In vitro antituberculosis activity of a new antibacterial substance ofloxacin (DL8280).

Authors:  M Tsukamura
Journal:  Am Rev Respir Dis       Date:  1985-03

5.  Comparative in vitro activities of ciprofloxacin and other 4-quinolones against Mycobacterium tuberculosis and Mycobacterium intracellulare.

Authors:  C H Fenlon; M H Cynamon
Journal:  Antimicrob Agents Chemother       Date:  1986-03       Impact factor: 5.191
  5 in total
  3 in total

Review 1.  Use of aminoglycosides in treatment of infections due to intracellular bacteria.

Authors:  M Maurin; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  2001-11       Impact factor: 5.191

2.  Comparison of in vitro antimicrobial susceptibilities of Mycobacterium avium-M. intracellulare strains from patients with acquired immunodeficiency syndrome (AIDS), patients without AIDS, and animal sources.

Authors:  S K Byrne; G L Geddes; J L Isaac-Renton; W A Black
Journal:  Antimicrob Agents Chemother       Date:  1990-07       Impact factor: 5.191

Review 3.  Fluoroquinolone antimicrobial agents.

Authors:  J S Wolfson; D C Hooper
Journal:  Clin Microbiol Rev       Date:  1989-10       Impact factor: 26.132
  3 in total

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