| Literature DB >> 31432432 |
Tongjian You1, Elisa F Ogawa2,3, Saurja Thapa4, Yurun Cai4, Gloria Y Yeh5,6,7, Peter M Wayne6,7, Ling Shi4, Suzanne G Leveille4,5,6.
Abstract
The purpose of this exploratory study was to examine the effects of Tai Chi on blood levels of beta endorphin (β-endorphin) and inflammatory markers in older adults with chronic pain. Forty community-dwelling older adults with chronic pain were randomized to Tai Chi or light physical exercise, and each offered twice weekly for 12 weeks. Following the 12-week intervention, neither Tai Chi nor light physical exercise changed levels of β-endorphin and inflammatory markers. However, in older adults who completed 70% or more classes, Tai Chi significantly lowered levels of β-endorphin (p < 0.05), whereas light physical exercise did not change levels of β-endorphin. The results suggest that Tai Chi may reduce levels of β-endorphin in older adults with chronic pain. Future studies are needed to better understand the role of the opioid analgesic system and immune system in regulating pain with aging and the long-term effects of Tai Chi on pain-related biomarkers.Entities:
Keywords: Beta endorphin; Chronic pain; Inflammation; Older adults; Tai Chi
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Year: 2019 PMID： 31432432 PMCID： PMC7031034 DOI： 10.1007/s40520-019-01316-1
Source DB: PubMed Journal: Aging Clin Exp Res ISSN： 1594-0667 Impact factor: 3.636