Valentina Biagioli1, Michela Piredda2, Ombretta Annibali3, Maria Cristina Tirindelli3, Adriana Pignatelli4, Francesco Marchesi5, Maria Rita Mauroni6, Sonia Soave7, Elisabetta Del Giudice8, Elena Ponticelli9, Marco Clari10, Sandra Cavallero11, Pierina Monni12, Laura Ottani13, Simona Sica14, Marco Cioce15, Lorella Cappucciati16, Francesca Bonifazi17, Rosaria Alvaro1, Maria Grazia De Marinis2, Gianpaolo Gargiulo18. 1. Department of Biomedicine and Prevention, Faculty of Medicine, School of Nursing, Tor Vergata University, Rome, Italy. 2. Research Unit Nursing Science, Campus Bio-Medico di Roma University, Rome, Italy. 3. Haematology, Stem Cell Transplantation, Transfusion Medicine and Cellular Therapy Unit, Campus Bio-Medico di Roma University, Rome, Italy. 4. Quality Office, Regina Elena National Cancer Institute, Rome, Italy. 5. Hematology and Stem Cell Transplant Unit, Regina Elena National Cancer Institute, Rome, Italy. 6. Haematology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy. 7. Stem Cell Transplant Unit, Fondazione Policlinico Tor Vergata, Rome, Italy. 8. Stem Cell Transplant Unit, S. Camillo-Forlanini Hospital, Rome, Italy. 9. Department of Oncology, Città della Salute e della Scienza University Hospital, Turin, Italy. 10. Department of Public Health and Paediatrics, University of Turin, Turin, Italy. 11. Haematology Unit, S. Croce e Carle Hospital, Cuneo, Italy. 12. Haematology/Oncology and Specialised Medicine Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy. 13. Bone Marrow Transplant Centre, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy. 14. Institute of Haematology, Cattolica del Sacro Cuore University, Rome, Italy. 15. Haematology Unit, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy. 16. Oncology-Hematology Department, Hospital of Piacenza, Piacenza, Italy. 17. Institute of Hematology and Medical Oncology "Seràgnoli", S. Orsola-Malpighi University Hospital, Alma Mater Studiorum University of Bologna, Bologna, Italy. 18. Haematology and Haematopoietic Stem Cell Transplantation Unit, Federico II University Hospital, Naples, Italy.
Abstract
OBJECTIVES: To identify which factors can influence the patients' perception of protective isolation following Haematopoietic Stem Cell Transplantation (HSCT). METHODS: This is a prospective study conducted in 10 Italian centres, members of the Italian Group of stem cell transplant (GITMO). Patients' perception of protective isolation was assessed using the ISOLA scale between 7 and 9 days post-transplant. Statistical linear regression analysis was performed. RESULTS: The participants were 182 adult patients receiving autologous (48%) or allogeneic (52%) HSCT in protective isolation. Male sex (β = .152), education level (β = -.245), double room (β = .186), satisfaction with visiting hours (β = -.174) and emotional support from nurses (β = -.169) were independently associated with isolation-related suffering. Significant predictors of the relationship with oneself included body temperature (β = -.179), fatigue (β = -.192) and emotional support from nurses (β = -.292). Factors independently associated with the relationship with others were education (β = -.230), chemotherapy cycles (β = -.218), pain (β = .150) and satisfaction with visiting hours (β = -.162). CONCLUSION: Healthcare providers should pay greater attention in caring for those patients who are at risk for a negative isolation experience. Nurses should provide emotional support.
OBJECTIVES: To identify which factors can influence the patients' perception of protective isolation following Haematopoietic Stem Cell Transplantation (HSCT). METHODS: This is a prospective study conducted in 10 Italian centres, members of the Italian Group of stem cell transplant (GITMO). Patients' perception of protective isolation was assessed using the ISOLA scale between 7 and 9 days post-transplant. Statistical linear regression analysis was performed. RESULTS: The participants were 182 adult patients receiving autologous (48%) or allogeneic (52%) HSCT in protective isolation. Male sex (β = .152), education level (β = -.245), double room (β = .186), satisfaction with visiting hours (β = -.174) and emotional support from nurses (β = -.169) were independently associated with isolation-related suffering. Significant predictors of the relationship with oneself included body temperature (β = -.179), fatigue (β = -.192) and emotional support from nurses (β = -.292). Factors independently associated with the relationship with others were education (β = -.230), chemotherapy cycles (β = -.218), pain (β = .150) and satisfaction with visiting hours (β = -.162). CONCLUSION: Healthcare providers should pay greater attention in caring for those patients who are at risk for a negative isolation experience. Nurses should provide emotional support.