Literature DB >> 31422362

Left atrial dimension and cardiovascular outcomes in patients with and without atrial fibrillation: a systematic review and meta-analysis.

Lorin Froehlich1,2, Pascal Meyre1,2, Stefanie Aeschbacher1,2, Steffen Blum1,2, Daniela Djokic2, Michael Kuehne1,2, Stefan Osswald1,2, Beat A Kaufmann1,2, David Conen3,4.   

Abstract

OBJECTIVE: The prognostic value of left atrial (LA) dimensions may differ between patients with and without atrial fibrillation (AF).
METHODS: MEDLINE and EMBASE were searched for studies that investigated the association between LA echocardiographic parameters measured by transthoracic echocardiography and cardiovascular outcomes in patients with or without AF. Data were independently abstracted by two reviewers and pooled using random-effects meta-analysis. The primary outcome was incident stroke or thromboembolic events. Secondary outcomes were heart failure, all-cause mortality and major adverse cardiac events (MACE).
RESULTS: Twenty-three studies of patients with AF (14 939 patients) and 68 studies of patients without AF (50 720 patients) in this systematic review. Increasing LA diameter was significantly associated with stroke and thromboembolic events in patients without AF (risk ratio (RR) 1.38, 95% CI 1.02 to 1.87; p=0.03), but not in patients with AF (RR 1.02, 95% CI 0.98 to 1.07; p=0.27; p for difference=0.05). Increasing LA diameter index was significantly associated with MACE in patients with AF (RR 1.13, 95% CI 1.09 to 1.17; p<0.001) and in patients without AF (RR 2.98, 95% CI 1.90 to 4.66; p<0.001), with stronger effects in non-AF populations (p for difference <0.001). Greater LA volume index was significantly associated with the risk of MACE in patients with AF (RR 1.01, 95% CI 1.00 to 1.02; p=0.03) and in non-AF populations (RR 1.08, 95% CI 1.05 to 1.10; p<0.001), the association being stronger in individuals without AF (p for difference <0.001).
CONCLUSIONS: Larger LA parameters were associated with various adverse cardiovascular events. Many of these associations were stronger in individuals without AF, highlighting the potential importance of LA myopathy. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  atrial fibrillation; echocardiogram; left atrial dimensions; meta-analysis; systematic review

Mesh：

Year:  2019        PMID： 31422362     DOI： 10.1136/heartjnl-2019-315174

Source DB:  PubMed          Journal:  Heart        ISSN： 1355-6037            Impact factor:   5.994


  13 in total

Review 1.  Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community.

Authors:  Ramachandran S Vasan; Elman Martin Urbina; Ling Jin; Vanessa Xanthakis
Journal:  Curr Cardiol Rep       Date:  2021-06-03       Impact factor: 2.931

2.  Clinical impact of echocardiography parameters and molecular biomarkers in heart failure: Correlation of ACE2 and MCP-1 polymorphisms with echocardiography parameters: A comparative study.

Authors:  Mălina Suciu-Petrescu; Anamaria Truta; Mihai Domnutiu Suciu; Adrian Pavel Trifa; Denisa Petrescu; Horia Ștefan Roșianu; Octavia Sabin; Daciana Elena Popa; Antonia Eugenia Macarie; Ștefan Cristian Vesa; Anca Dana Buzoianu
Journal:  Exp Ther Med       Date:  2021-04-28       Impact factor: 2.447

Review 3.  Left Atrial Cardiomyopathy - A Challenging Diagnosis.

Authors:  Fabienne Kreimer; Michael Gotzmann
Journal:  Front Cardiovasc Med       Date:  2022-06-30

Review 4.  Atrial fibrillation and stroke: importance of left atrium as assessed by echocardiography.

Authors:  Yoshinobu Suwa; Yoko Miyasaka; Naoki Taniguchi; Shoko Harada; Eri Nakai; Ichiro Shiojima
Journal:  J Echocardiogr       Date:  2022-01-23

5.  Predictive value of echocardiographic left atrial size for incident stoke and stroke cause mortality: a population-based study.

Authors:  Tan Li; Guangxiao Li; Xiaofan Guo; Zhao Li; Jun Yang; Yingxian Sun
Journal:  BMJ Open       Date:  2021-03-08       Impact factor: 2.692

6.  Prognostic value of reduction in left atrial size during a follow-up of heart failure: an observational study.

Authors:  Masayuki Shiba; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Yugo Yamashita; Moritake Iguchi; Kazuya Nagao; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
Journal:  BMJ Open       Date:  2021-02-19       Impact factor: 2.692

7.  Revisiting left atrial volumetry by magnetic resonance imaging: the role of atrial shape and 3D angle between left ventricular and left atrial axis.

Authors:  Jouni K Kuusisto; Pauli A K Pöyhönen; Jani Pirinen; Lauri J Lehmonen; Heli P Räty; Nicolas Martinez-Majander; Jukka Putaala; Juha Sinisalo; Vesa Järvinen
Journal:  BMC Med Imaging       Date:  2021-11-09       Impact factor: 1.930

8.  Atri-U: assisted image analysis in routine cardiovascular magnetic resonance volumetry of the left atrium.

Authors:  Constantin Anastasopoulos; Shan Yang; Maurice Pradella; Tugba Akinci D'Antonoli; Sven Knecht; Joshy Cyriac; Marco Reisert; Elias Kellner; Rita Achermann; Philip Haaf; Bram Stieltjes; Alexander W Sauter; Jens Bremerich; Gregor Sommer; Ahmed Abdulkadir
Journal:  J Cardiovasc Magn Reson       Date:  2021-11-11       Impact factor: 5.364

9.  Prognostic power of conventional echocardiography in individuals without history of cardiovascular diseases: A systematic review and meta-analysis.

Authors:  Luciana Pereira Fernandes; Ana Terra Fonseca Barreto; Mansueto Gomes Neto; Edmundo José Nassri Câmara; André Rodrigues Durães; Leonardo Roever; Roque Aras-Júnior
Journal:  Clinics (Sao Paulo)       Date:  2021-06-28       Impact factor: 2.365

Review 10.  Expert opinion paper on cardiac imaging after ischemic stroke.

Authors:  Renate B Schnabel; Stephan Camen; Fabian Knebel; Andreas Hagendorff; Udo Bavendiek; Michael Böhm; Wolfram Doehner; Matthias Endres; Klaus Gröschel; Andreas Goette; Hagen B Huttner; Christoph Jensen; Paulus Kirchhof; Grigorios Korosoglou; Ulrich Laufs; Jan Liman; Caroline Morbach; Darius Günther Nabavi; Tobias Neumann-Haefelin; Waltraud Pfeilschifter; Sven Poli; Timolaos Rizos; Andreas Rolf; Joachim Röther; Wolf Rüdiger Schäbitz; Thorsten Steiner; Götz Thomalla; Rolf Wachter; Karl Georg Haeusler
Journal:  Clin Res Cardiol       Date:  2021-06-18       Impact factor: 5.460
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