Literature DB >> 31421905

Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment.

Gabriele Sulli1, Michael Tun Yin Lam2, Satchidananda Panda3.   

Abstract

Circadian clocks constitute the evolutionary molecular machinery that dictates the temporal regulation of physiology to maintain homeostasis. Disruption of the circadian rhythm plays a key role in tumorigenesis and facilitates the establishment of cancer hallmarks. Conversely, oncogenic processes directly weaken circadian rhythms. Pharmacological modulation of core clock genes is a new approach in cancer therapy. The integration of circadian biology into cancer research offers new options for making cancer treatment more effective, encompassing the prevention, diagnosis, and treatment of this devastating disease. This review highlights the role of the circadian clock in tumorigenesis and cancer hallmarks, and discusses how pharmacological modulation of circadian clock genes can lead to new therapeutic options.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  cancer hallmarks; cancer therapy; circadian clock; circadian rhythms; tumorigenesis

Mesh：

Substances：

Year:  2019        PMID： 31421905      PMCID： PMC7120250          DOI： 10.1016/j.trecan.2019.07.002

Source DB:  PubMed          Journal:  Trends Cancer        ISSN： 2405-8025


  152 in total

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Journal:  Mol Cancer Ther       Date:  2012-03-02       Impact factor: 6.261

2.  Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells.

Authors:  Brittney Jung-Hynes; Wei Huang; Russel J Reiter; Nihal Ahmad
Journal:  J Pineal Res       Date:  2010-05-27       Impact factor: 13.007

3.  Circadian genes and breast cancer susceptibility in rotating shift workers.

Authors:  Genevieve M Monsees; Peter Kraft; Susan E Hankinson; David J Hunter; Eva S Schernhammer
Journal:  Int J Cancer       Date:  2012-09-07       Impact factor: 7.396

Review 4.  Circadian variation of cell proliferation and cell cycle protein expression in man: clinical implications.

Authors:  G A Bjarnason; R Jordan
Journal:  Prog Cell Cycle Res       Date:  2000

5.  c-MYC targets the central oscillator gene Per1 and is regulated by the circadian clock at the post-transcriptional level.

Authors:  Anastasia Repouskou; Anastasia Prombona
Journal:  Biochim Biophys Acta       Date:  2016-02-02

6.  Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.

Authors:  Susie Lee; Lawrence A Donehower; Alan J Herron; David D Moore; Loning Fu
Journal:  PLoS One       Date:  2010-06-07       Impact factor: 3.240

7.  PI3K regulates BMAL1/CLOCK-mediated circadian transcription from the Dbp promoter.

Authors:  Yoshikazu Morishita; Daiki Miura; Satoshi Kida
Journal:  Biosci Biotechnol Biochem       Date:  2016-03-29       Impact factor: 2.043

Review 8.  Crosstalk between metabolism and circadian clocks.

Authors:  Hans Reinke; Gad Asher
Journal:  Nat Rev Mol Cell Biol       Date:  2019-04       Impact factor: 94.444

9.  Analysis of polymorphisms in the circadian-related genes and breast cancer risk in Norwegian nurses working night shifts.

Authors:  Shanbeh Zienolddiny; Aage Haugen; Jenny-Anne Sigstad Lie; Helge Kjuus; Kristine Haugen Anmarkrud; Kristina Kjærheim
Journal:  Breast Cancer Res       Date:  2013       Impact factor: 6.466

10.  Expression of the Circadian Clock Gene BMAL1 Positively Correlates With Antitumor Immunity and Patient Survival in Metastatic Melanoma.

Authors:  Leonardo Vinícius Monteiro de Assis; Gabriela Sarti Kinker; Maria Nathália Moraes; Regina P Markus; Pedro Augusto Fernandes; Ana Maria de Lauro Castrucci
Journal:  Front Oncol       Date:  2018-06-12       Impact factor: 6.244
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  83 in total

Review 1.  Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models.

Authors:  Ji Ye Lim; Xiang-Dong Wang
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2020-02-05       Impact factor: 4.698

Review 2.  HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer.

Authors:  Ellen C de Heer; Mathilde Jalving; Adrian L Harris
Journal:  J Clin Invest       Date:  2020-10-01       Impact factor: 14.808

Review 3.  Exploring the link between chronobiology and drug delivery: effects on cancer therapy.

Authors:  Tânia Albuquerque; Ana R Neves; Telma Quintela; Diana Costa
Journal:  J Mol Med (Berl)       Date:  2021-07-02       Impact factor: 4.599

Review 4.  Clocking cancer: the circadian clock as a target in cancer therapy.

Authors:  Francesca Battaglin; Priscilla Chan; Yuanzhong Pan; Shivani Soni; Meng Qu; Erin R Spiller; Sofi Castanon; Evanthia T Roussos Torres; Shannon M Mumenthaler; Steve A Kay; Heinz-Josef Lenz
Journal:  Oncogene       Date:  2021-04-12       Impact factor: 9.867

5.  Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans.

Authors:  Bala S C Koritala; Kenneth I Porter; Osama A Arshad; Rajendra P Gajula; Hugh D Mitchell; Tarana Arman; Mugimane G Manjanatha; Justin Teeguarden; Hans P A Van Dongen; Jason E McDermott; Shobhan Gaddameedhi
Journal:  J Pineal Res       Date:  2021-03-14       Impact factor: 13.007

Review 6.  Context-Dependent Glioblastoma-Macrophage/Microglia Symbiosis and Associated Mechanisms.

Authors:  Wenjing Xuan; Maciej S Lesniak; Charles David James; Amy B Heimberger; Peiwen Chen
Journal:  Trends Immunol       Date:  2021-03-01       Impact factor: 16.687

Review 7.  Evaluation and Management of Sleep and Circadian Rhythm Disturbance in Cancer.

Authors:  Diwakar D Balachandran; Michelle A Miller; Saadia A Faiz; Sriram Yennurajalingam; Pasquale F Innominato
Journal:  Curr Treat Options Oncol       Date:  2021-07-02

8.  Transcription factor networks of oligodendrogliomas treated with adjuvant radiotherapy or observation inform prognosis.

Authors:  Jonathan So; Yasin Mamatjan; Gelareh Zadeh; Kenneth Aldape; Fabio Y Moraes
Journal:  Neuro Oncol       Date:  2021-05-05       Impact factor: 12.300

Review 9.  Circadian regulation of cancer cell and tumor microenvironment crosstalk.

Authors:  Wenjing Xuan; Fatima Khan; Charles David James; Amy B Heimberger; Maciej S Lesniak; Peiwen Chen
Journal:  Trends Cell Biol       Date:  2021-07-13       Impact factor: 20.808

Review 10.  Designing Relevant Preclinical Rodent Models for Studying Links Between Nutrition, Obesity, Metabolism, and Cancer.

Authors:  Elaine M Glenny; Michael F Coleman; Erin D Giles; Elizabeth A Wellberg; Stephen D Hursting
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