Literature DB >> 27374457

Nanoparticle design considerations for molecular imaging of apoptosis: Diagnostic, prognostic, and therapeutic value.

Ronak Savla1, Tamara Minko2.   

Abstract

The present review analyzes various approaches for the design and synthesis of different nanoparticles for imaging and therapy. Nanoparticles for computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET) and optical imaging are discussed. The influence of nanoparticle size, shape, surface charge, composition, surface functionalization, active targeting and other factors on imaging and therapeutic efficacy is analyzed. Cyto- and genotoxicity of nanoparticles are also discussed. Special attention in the review is paid to the imaging of apoptotic tissues and cells in different diseases.
Copyright © 2016. Published by Elsevier B.V.

Keywords:  Apoptosis; Computed tomography; Magnetic resonance; Nanoparticle; Theranostic

Mesh：

Year:  2016        PMID： 27374457     DOI： 10.1016/j.addr.2016.06.016

Source DB:  PubMed          Journal:  Adv Drug Deliv Rev        ISSN： 0169-409X            Impact factor:   15.470


  15 in total

Review 1.  Nanoparticle Interactions with the Tumor Microenvironment.

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Review 2.  Precision targeted therapy of ovarian cancer.

Authors:  Justin Sapiezynski; Oleh Taratula; Lorna Rodriguez-Rodriguez; Tamara Minko
Journal:  J Control Release       Date:  2016-10-14       Impact factor: 9.776

Review 3.  Neurotheranostics as personalized medicines.

Authors:  Bhavesh D Kevadiya; Brendan M Ottemann; Midhun Ben Thomas; Insiya Mukadam; Saumya Nigam; JoEllyn McMillan; Santhi Gorantla; Tatiana K Bronich; Benson Edagwa; Howard E Gendelman
Journal:  Adv Drug Deliv Rev       Date:  2018-10-26       Impact factor: 15.470

4.  Lanthanide-doped nanoparticles conjugated with an anti-CD33 antibody and a p53-activating peptide for acute myeloid leukemia therapy.

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Journal:  Biomaterials       Date:  2018-03-14       Impact factor: 12.479

5.  Carbon quantum dots-Annexin V probe: photoinduced electron transfer mechanism, phosphatidylserine detection, and apoptotic cell imaging.

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6.  Optimization and comparison of CD4-targeting lipid-polymer hybrid nanoparticles using different binding ligands.

Authors:  Shijie Cao; Yonghou Jiang; Claire N Levy; Sean M Hughes; Hangyu Zhang; Florian Hladik; Kim A Woodrow
Journal:  J Biomed Mater Res A       Date:  2018-01-10       Impact factor: 4.854

7.  Enhancing the Efficacy of Metal-Free MRI Contrast Agents via Conjugating Nitroxides onto PEGylated Cross-Linked Poly(Carboxylate Ester).

Authors:  Shiwei Guo; Xiaoming Wang; Yan Dai; Xinghang Dai; Zhiqian Li; Qiang Luo; Xiuli Zheng; Zhongwei Gu; Hu Zhang; Qiyong Gong; Kui Luo
Journal:  Adv Sci (Weinh)       Date:  2020-06-03       Impact factor: 16.806

8.  Artificially controlled degradable nanoparticles for contrast switch MRI and programmed cancer therapy.

Authors:  Tianyang Yun; Yuxin Liu; Shaoqiong Yi; Qi Jia; Yang Liu; Jing Zhou
Journal:  Int J Nanomedicine       Date:  2018-10-24

9.  Gold Nanorods for Light-Based Lung Cancer Theranostics.

Authors:  Oscar B Knights; James R McLaughlan
Journal:  Int J Mol Sci       Date:  2018-10-25       Impact factor: 5.923

10.  One-Step Facile Synthesis of Highly Magnetic and Surface Functionalized Iron Oxide Nanorods for Biomarker-Targeted Applications.

Authors:  Anamaria Orza; Hui Wu; Yaolin Xu; Qiong Lu; Hui Mao
Journal:  ACS Appl Mater Interfaces       Date:  2017-06-06       Impact factor: 9.229
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