Literature DB >> 31403368

Deep Brain Stimulation at End of Life: Clinical and Ethical Considerations.

Lauren R Sankary1, Paul J Ford1, Andre G Machado2, Laura J Hoeksema3, Renato V Samala3, David J Harris3.   

Abstract

Deep brain stimulation (DBS) is an implanted neurological device effective in treating motor symptoms of Parkinson disease (PD), such as tremor, rigidity, and bradykinesia. More than 150,000 patients worldwide have been implanted with DBS devices. Questions arise at the end of life concerning how to provide best care for patients with DBS, including its continued benefit or potential complications, yet, no published articles provide guidance for hospice providers regarding the management of DBS devices in end-of-life care. With contributions from hospice physicians, a neurosurgeon, and ethicists, this article provides recommendations to address clinical and ethical challenges in optimizing DBS for patients with PD nearing the end of life.

Entities:  

Keywords:  DBS; Parkinson disease; deep brain stimulation; end of life; ethics; hospice

Mesh：

Year:  2019        PMID： 31403368      PMCID： PMC7104899          DOI： 10.1089/jpm.2019.0129

Source DB:  PubMed          Journal:  J Palliat Med        ISSN： 1557-7740            Impact factor:   2.947


  13 in total

1.  A randomized trial of deep-brain stimulation for Parkinson's disease.

Authors:  Günther Deuschl; Carmen Schade-Brittinger; Paul Krack; Jens Volkmann; Helmut Schäfer; Kai Bötzel; Christine Daniels; Angela Deutschländer; Ulrich Dillmann; Wilhelm Eisner; Doreen Gruber; Wolfgang Hamel; Jan Herzog; Rüdiger Hilker; Stephan Klebe; Manja Kloss; Jan Koy; Martin Krause; Andreas Kupsch; Delia Lorenz; Stefan Lorenzl; H Maximilian Mehdorn; Jean Richard Moringlane; Wolfgang Oertel; Marcus O Pinsker; Heinz Reichmann; Alexander Reuss; Gerd-Helge Schneider; Alfons Schnitzler; Ulrich Steude; Volker Sturm; Lars Timmermann; Volker Tronnier; Thomas Trottenberg; Lars Wojtecki; Elisabeth Wolf; Werner Poewe; Jürgen Voges
Journal:  N Engl J Med       Date:  2006-08-31       Impact factor: 91.245

2.  Deep brain stimulation for Parkinson's disease: surgical technique and perioperative management.

Authors:  Andre Machado; Ali R Rezai; Brian H Kopell; Robert E Gross; Ashwini D Sharan; Alim-Louis Benabid
Journal:  Mov Disord       Date:  2006-06       Impact factor: 10.338

Review 3.  Parkinson's disease: clinical features and diagnosis.

Authors:  J Jankovic
Journal:  J Neurol Neurosurg Psychiatry       Date:  2008-04       Impact factor: 10.154

4.  Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial.

Authors:  Michael S Okun; Bruno V Gallo; George Mandybur; Jonathan Jagid; Kelly D Foote; Fredy J Revilla; Ron Alterman; Joseph Jankovic; Richard Simpson; Fred Junn; Leo Verhagen; Jeff E Arle; Blair Ford; Robert R Goodman; R Malcolm Stewart; Stacy Horn; Gordon H Baltuch; Brian H Kopell; Frederick Marshall; Delea Peichel; Rajesh Pahwa; Kelly E Lyons; Alexander I Tröster; Jerrold L Vitek; Michele Tagliati
Journal:  Lancet Neurol       Date:  2012-01-11       Impact factor: 44.182

5.  Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial.

Authors:  Adrian Williams; Steven Gill; Thelekat Varma; Crispin Jenkinson; Niall Quinn; Rosalind Mitchell; Richard Scott; Natalie Ives; Caroline Rick; Jane Daniels; Smitaa Patel; Keith Wheatley
Journal:  Lancet Neurol       Date:  2010-04-29       Impact factor: 44.182

6.  Survival in patients with Parkinson's disease after deep brain stimulation or medical management.

Authors:  Frances M Weaver; Kevin T Stroupe; Bridget Smith; Beverly Gonzalez; Zhiping Huo; Lishan Cao; Dolores Ippolito; Kenneth A Follett
Journal:  Mov Disord       Date:  2017-11-18       Impact factor: 10.338

7.  Deep brain stimulation and the ethics of protection and caring for the patient with Parkinson's dementia.

Authors:  Sierra Farris; Paul Ford; Joseph DeMarco; Monique L Giroux
Journal:  Mov Disord       Date:  2008-10-30       Impact factor: 10.338

8.  Long-term follow up of bilateral deep brain stimulation of the subthalamic nucleus in patients with advanced Parkinson disease.

Authors:  Galit Kleiner-Fisman; David N Fisman; Elspeth Sime; Jean A Saint-Cyr; Andres M Lozano; Anthony E Lang
Journal:  J Neurosurg       Date:  2003-09       Impact factor: 5.115

Review 9.  Parkinson's Disease: From Pathogenesis to Pharmacogenomics.

Authors:  Ramón Cacabelos
Journal:  Int J Mol Sci       Date:  2017-03-04       Impact factor: 5.923

10.  Clinical aspects of palliative care in advanced Parkinson's disease.

Authors:  Johan Lokk; Ahmad Delbari
Journal:  BMC Palliat Care       Date:  2012-10-25       Impact factor: 3.234
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  2 in total

1.  When Should Neuroendovascular Care for Patients With Acute Stroke Be Palliative?

Authors:  Michael J Young; Robert W Regenhardt; Leonard L Sokol; Thabele M Leslie-Mazwi
Journal:  AMA J Ethics       Date:  2021-10-01

Review 2.  Restoring vision using optogenetics without being blind to the risks.

Authors:  Alexander R Harris; Frederic Gilbert
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-11-01       Impact factor: 3.117
  2 in total

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