Literature DB >> 31399317

A systematic review of the safety and efficacy of non-operative management in patients with high grade liver injury.

Yosuf Saqib1.   

Abstract

INTRODUCTION: The liver is the most frequently damaged organ in blunt abdominal trauma. It is widely accepted that hemodynamically stable patients with low-grade liver trauma should be treated with non-operative management, however there is controversy surrounding its safety and efficacy in high-grade trauma. The purpose of this review is to investigate the role of non-operative management in patients with high-grade liver trauma.
METHODS: PubMed and reference lists of PubMed articles were searched to find studies that examined the efficacy of non-operative management in high-grade liver injury patients, and compare it to operative management. Non-operative management was considered successful if rescue surgery was avoided. Outcomes considered were success, mortality, and complication rates.
RESULTS: The electronic search revealed 2662 records, 8 of which met the inclusion criteria. All 8 studies contained results suggesting that non-operative management was safe and effective in hemodynamically stable patients with high-grade liver trauma. By combining the outcomes of the different studies, non-operative management had a high success rate of 92.4% (194/210) in high-grade liver trauma patients, which was near the overall 95.0% non-operative management success rate. Non-operative management also had mortality and complication rates of 4.6% (9/194) and 9.7% (7/72) in high-grade injury patients, respectively, compared to operative management's 17.6% (26/148) and 45.5% (5/11).
CONCLUSION: Non-operative management of liver trauma is safe and effective in hemodynamically stable patients with high-grade liver injury. It is associated with significantly lower mortality compared with operative management. More studies are required to evaluate complications of non-operative management in high-grade liver injury.
Copyright © 2019 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Angioembolization; Hemodynamic stability; High-grade liver trauma; Non-operative management; Operative management

Year:  2019        PMID: 31399317     DOI: 10.1016/j.surge.2019.07.001

Source DB:  PubMed          Journal:  Surgeon        ISSN: 1479-666X            Impact factor:   2.392


  2 in total

1.  Grade of injury, not initial management, is associated with unplanned interventions in liver injury.

Authors:  Armin Edalatpour; Brian T Young; Laura R Brown; Esther S Tseng; Husayn A Ladhani; Nimitt J Patel; Jeffrey A Claridge; Vanessa P Ho
Journal:  Injury       Date:  2020-03-29       Impact factor: 2.586

Review 2.  Clinical outcomes of non-operative management and clinical observation in non-angioembolised hepatic trauma: A systematic review of the literature.

Authors:  Francesco Virdis; Mauro Podda; Salomone Di Saverio; Jayant Kumar; Roberto Bini; Carlos Pilasi; Isabella Reccia
Journal:  Chin J Traumatol       Date:  2022-04-13
  2 in total

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