Literature DB >> 3139596

A synthetic adjuvant effective in inducing antitumor immunity.

T Kataoka1, T Tokunaga.   

Abstract

Guinea pigs which were injected repeatedly with a mixture of a 3M KCl extract of line 10 tumor and 6-O-(2-tetradecyl-hexadecanoyl)-muramyl-dipeptide (B30-MDP) rejected a tumor graft of line 10. Such an adjuvant effect of B30-MDP was also demonstrated when X-ray-treated line 10 cells were mixed with B30-MDP dissolved in phosphate-buffered saline and inoculated into the animals.

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Year:  1988        PMID: 3139596      PMCID: PMC5917595          DOI: 10.1111/j.1349-7006.1988.tb00042.x

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN: 0910-5050


  9 in total

1.  Protective tumor immunity induced by potassium chloride extracts of guinea pig hepatomas.

Authors:  M S Meltzer; E J Leonard; A S Hardy; H J Rapp
Journal:  J Natl Cancer Inst       Date:  1975-06       Impact factor: 13.506

2.  Immunotherapy of established micrometastases with Bacillus Calmette-Guérin tumor cell vaccine.

Authors:  M G Hanna; L C Peters
Journal:  Cancer Res       Date:  1978-01       Impact factor: 12.701

3.  Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives.

Authors:  F Ellouz; A Adam; R Ciorbaru; E Lederer
Journal:  Biochem Biophys Res Commun       Date:  1974-08-19       Impact factor: 3.575

4.  Antigenic specificity of hepatomas induced in strain-2 guinea pigs by diethylnitrosamine.

Authors:  B Zbar; H T Wepsic; H J Rapp; T Borsos; B S Kronman; W H Churchill
Journal:  J Natl Cancer Inst       Date:  1969-10       Impact factor: 13.506

5.  Antigenicity of a new diethylnitrosamine-induced transplantable guinea pig hepatoma: pathology and formation of ascites variant.

Authors:  H J Rapp; W H Churchill; B S Kronman; R T Rolley; W G Hammond; T Borsos
Journal:  J Natl Cancer Inst       Date:  1968-07       Impact factor: 13.506

6.  Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: adaptability to various vehicles and pyrogenicity.

Authors:  M Tsujimoto; S Kotani; F Kinoshita; S Kanoh; T Shiba; S Kusumoto
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

7.  Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: dose-response and local reactions observed with selected compounds.

Authors:  M Tsujimoto; S Kotani; T Shiba; S Kusumoto
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

8.  Immunoadjuvant activities of synthetic N-acetyl-muramyl-peptides or -amino acids.

Authors:  S Kotani; Y Watanabe; F Kinoshita; T Shimono; I Morisaki
Journal:  Biken J       Date:  1975-06

9.  Immunoadjuvant activities of synthetic 6-O-acyl-N-acetylmuramyl-L-alanyl-D-isoglutamine with special reference to the effect of its administration with liposomes.

Authors:  S Kotani; F Kinoshita; I Morisaki; T Shimono; T Okunaga; H Takada; M Tsujimoto; Y Watanabe; K Kato; T Shiba; S Kusumoto; S Okada
Journal:  Biken J       Date:  1977-12
  9 in total
  1 in total

Review 1.  Harnessing the untapped potential of nucleotide-binding oligomerization domain ligands for cancer immunotherapy.

Authors:  Sanja Nabergoj; Irena Mlinarič-Raščan; Žiga Jakopin
Journal:  Med Res Rev       Date:  2018-12-13       Impact factor: 12.944

  1 in total

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