| Literature DB >> 166188 |
M S Meltzer, E J Leonard, A S Hardy, H J Rapp.
Abstract
Tumor-specific antigens of cells of the diethylnitrosamine-induced hepatomas in strain-2 guinea pigs were extracted with 3 M KCl. Immunization of normal animals with the extracted tumor antigens in adjuvant protected them against a subsequent challenge with viable tumor cells. Extracted tumor-specific antigens were less effective immunogens than viable tumor cells for both of two antigenically distinct lines.Entities:
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Year: 1975 PMID： 166188 DOI： 10.1093/jnci/54.6.1349
Source DB: PubMed Journal: J Natl Cancer Inst ISSN： 0027-8874 Impact factor: 13.506