| Literature DB >> 31395665 |
W M Freeze1,2, D N Ter Weele3, W M Palm2, R W van Hooren1, E I Hoff4, J F A Jansen2, H I L Jacobs1, F R Verhey1, W H Backes5.
Abstract
Pericortical enhancement on postcontrast FLAIR images is a marker for subtle leptomeningeal blood-brain barrier leakage. We explored the optimal FLAIR sequence parameters for the detection of low gadolinium concentrations within the CSF. On the basis of phantom experiments and human in vivo data, we showed that detection of subtle pericortical enhancement can be facilitated by using a relatively long TE. Future studies should choose their FLAIR sequence parameters carefully when assessing pericortical enhancement due to subtle blood-brain barrier leakage.Entities:
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Year: 2019 PMID: 31395665 PMCID: PMC7048436 DOI: 10.3174/ajnr.A6145
Source DB: PubMed Journal: AJNR Am J Neuroradiol ISSN: 0195-6108 Impact factor: 3.825