Literature DB >> 313936

Enhancement of insulin-induced prolactin secretion by fluoxetine in man.

A Masala, G Delitala, L Devilla, S Alagna, P P Rovasio.   

Abstract

Fluoxetine hydrochloride, a specific inhibitor of serotonin reuptake, was given orally to five adult males to study its effect on fasting and insulin-stimulated release of PRL. A 3-day course of fluoxetine (30 mg daily) had no demonstrable effect on fasting PRL levels. Fluoxetine significantly enhanced insulin-induced PRL release. These data suggest that serotoninergic pathways have little or no part in the control of spontaneous PRL secretion in man, whereas they may play a role in insulin-stimulated PRL release.

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Year:  1979        PMID： 313936     DOI： 10.1210/jcem-49-3-350

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  7 in total

1.  Effect of hypoglycaemia, TRH and levodopa on plasma growth hormone, prolactin, thyrotropin and cortisol in Parkinson's disease before and during therapy.

Authors:  H P Vogel; R Ketsche
Journal:  J Neurol       Date:  1986-06       Impact factor: 4.849

Review 2.  Drug-induced changes in prolactin secretion. Clinical implications.

Authors:  K Hell; H Wernze
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Nov-Dec

3.  The inability of dynamic tests of prolactin and TSH secretion to differentiate between tumorous and non-tumorous hyperprolactinemia.

Authors:  R W Prescott; D G Johnston; P K Taylor; J Haigh; D R Weightman; K Hall; D B Cook
Journal:  J Endocrinol Invest       Date:  1985-02       Impact factor: 4.256

4.  Dexfenfluramine-induced prolactin release as an index of central synaptosomal 5-hydroxytryptamine during treatment with fluoxetine.

Authors:  D K Sommers; M van Wyk; J R Snyman
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

Review 5.  Fluoxetine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness.

Authors:  P Benfield; R C Heel; S P Lewis
Journal:  Drugs       Date:  1986-12       Impact factor: 9.546

6.  Semisynthetic human insulin and purified pork insulin do not differ in their biological potency.

Authors:  P Arias; W Kerner; I Navascués; G Schäfauer; E F Pfeiffer
Journal:  Klin Wochenschr       Date:  1984-12-17

7.  Influence of inhibitors of serotonin uptake on intestinal epithelium and colorectal carcinomas.

Authors:  P J Tutton; D H Barkla
Journal:  Br J Cancer       Date:  1982-08       Impact factor: 7.640
  7 in total

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