| Literature DB >> 3139057 |
A Schön1, H Hottinger, D Söll.
Abstract
Aminoacylation studies with Lactobacillus bulgaricus show that this organism possesses glutamyl-tRNA synthetase activity; however, glutamyl-tRNA synthetase activity cannot be demonstrated. Instead, Glu-tRNAGln, which is formed by glutamyl-tRNA synthetase, is amidated by a specific amidotransferase to Gln-tRNAGln. The amide donor in this reaction is glutamine. Thus, Gln-tRNAGln in this organism is not formed by direct glutaminylation of tRNAGln, but instead by a pathway which involves misaminoacylation and transamidation.Entities:
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Year: 1988 PMID： 3139057 DOI： 10.1016/0300-9084(88)90212-x
Source DB: PubMed Journal: Biochimie ISSN： 0300-9084 Impact factor: 4.079