| Literature DB >> 25796611 |
Jennifer Shepherd1, Michael Ibba2.
Abstract
Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression. This review aims to bring together the results of intensive investigations into the synthesis, maturation, modification, aminoacylation, editing and recycling of bacterial transfer RNAs. Codon recognition at the ribosome as well as the ever-increasing number of alternative roles for transfer RNA outside of translation will be discussed in the specific context of bacterial cells. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.Keywords: aminoacylation; codon; modification; protein synthesis; tRNA; translation
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Year: 2015 PMID: 25796611 PMCID: PMC4542688 DOI: 10.1093/femsre/fuv004
Source DB: PubMed Journal: FEMS Microbiol Rev ISSN: 0168-6445 Impact factor: 16.408