Pilar Lopez-Garcia1, Stefania Ashby2, Pooja Patel2, Katherine M Pierce2, Monet Meyer2, Adi Rosenthal2, Madison Titone2, Cameron Carter3, Tara Niendam2. 1. Department of Psychiatry, Universidad Autonoma de Madrid, CIBERSAM, Madrid, Spain. Electronic address: p.lopez@uam.es. 2. Department of Psychiatry & Behavioral Sciences, University of California-Davis, Sacramento, CA, United States of America. 3. Department of Psychiatry & Behavioral Sciences, University of California-Davis, Sacramento, CA, United States of America; Center for Neuroscience, University of California-Davis, Davis, CA, United States of America.
Abstract
BACKGROUND: Although mental illness accounts for only 4% of aggressive behavior in the general population, there remains a modest association between aggressive behavior and psychotic disorders, particularly in the early stages of the illness. However, little is known about the specific factors associated to this increased risk. AIMS: The present study aims to assess the rates, characteristics and risk factors of aggressive behavior in first episode psychosis patients (FEP). METHOD: We conducted a retrospective chart review of 449 FEP patients recruited from an outpatient early psychosis clinic. Aggressive behavior and clinical information were rated based upon information gathered from the chart review of data collected at baseline and after 6 months of follow-up. RESULTS: Rates of aggressive behavior were 54.3% in FEP patients. Aggressive behavior was significantly associated with higher rates of history of birth complications, neurodevelopmental delays, learning difficulties, alcohol use disorders, and the clinical domain of poverty symptoms. In addition to aggressive behavior, 16.7% of FEP patients exhibited suicidal ideation or behaviors and 11.4% exhibited non-suicidal self-injurious behavior (NSSIB). In contrast to baseline, aggressive behaviors at 6 months follow up were almost entirely absent. CONCLUSIONS: Patients at early stages of psychosis have high rates of aggressive and suicidal behavior prior to contact with clinical services. Neurodevelopmental adversities, alcohol use disorders and poverty symptoms are associated to higher risk of aggression in early psychosis. Participation in early psychosis specialty care resulted in a dramatic reduction in aggressive behavior.
BACKGROUND: Although mental illness accounts for only 4% of aggressive behavior in the general population, there remains a modest association between aggressive behavior and psychotic disorders, particularly in the early stages of the illness. However, little is known about the specific factors associated to this increased risk. AIMS: The present study aims to assess the rates, characteristics and risk factors of aggressive behavior in first episode psychosispatients (FEP). METHOD: We conducted a retrospective chart review of 449 FEP patients recruited from an outpatient early psychosis clinic. Aggressive behavior and clinical information were rated based upon information gathered from the chart review of data collected at baseline and after 6 months of follow-up. RESULTS: Rates of aggressive behavior were 54.3% in FEP patients. Aggressive behavior was significantly associated with higher rates of history of birth complications, neurodevelopmental delays, learning difficulties, alcohol use disorders, and the clinical domain of poverty symptoms. In addition to aggressive behavior, 16.7% of FEP patients exhibited suicidal ideation or behaviors and 11.4% exhibited non-suicidal self-injurious behavior (NSSIB). In contrast to baseline, aggressive behaviors at 6 months follow up were almost entirely absent. CONCLUSIONS:Patients at early stages of psychosis have high rates of aggressive and suicidal behavior prior to contact with clinical services. Neurodevelopmental adversities, alcohol use disorders and poverty symptoms are associated to higher risk of aggressionin early psychosis. Participation in early psychosis specialty care resulted in a dramatic reduction in aggressive behavior.
Authors: Christopher R Bowie; Abraham Reichenberg; Thomas L Patterson; Robert K Heaton; Philip D Harvey Journal: Am J Psychiatry Date: 2006-03 Impact factor: 18.112
Authors: Francesco Dal Santo; Eduardo Fonseca-Pedrero; María Paz García-Portilla; Leticia González-Blanco; Pilar A Sáiz; Silvana Galderisi; Giulia Maria Giordano; Julio Bobes Journal: Eur Psychiatry Date: 2022-06-10 Impact factor: 7.156
Authors: Adi Rosenthal; Monet S Meyer; Danessa Mayo; Laura M Tully; Pooja Patel; Stefania Ashby; Madison Titone; Cameron S Carter; Tara A Niendam Journal: Early Interv Psychiatry Date: 2020-02-10 Impact factor: 2.732