Literature DB >> 31383717

2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus.

Martin Aringer1, Karen Costenbader2, David Daikh3, Ralph Brinks4, Marta Mosca5, Rosalind Ramsey-Goldman6, Josef S Smolen7, David Wofsy8, Dimitrios T Boumpas9,10, Diane L Kamen11, David Jayne12, Ricard Cervera13, Nathalie Costedoat-Chalumeau14, Betty Diamond15, Dafna D Gladman16, Bevra Hahn17, Falk Hiepe18, Søren Jacobsen19, Dinesh Khanna20, Kirsten Lerstrøm21, Elena Massarotti22,23, Joseph McCune20, Guillermo Ruiz-Irastorza24, Jorge Sanchez-Guerrero25,26, Matthias Schneider27, Murray Urowitz28, George Bertsias29, Bimba F Hoyer18,30, Nicolai Leuchten31, Chiara Tani32, Sara K Tedeschi23,33, Zahi Touma34, Gabriela Schmajuk3, Branimir Anic35, Florence Assan36, Tak Mao Chan37, Ann Elaine Clarke38, Mary K Crow39, László Czirják40, Andrea Doria41, Winfried Graninger42, Bernadett Halda-Kiss40, Sarfaraz Hasni43, Peter M Izmirly44, Michelle Jung38, Gábor Kumánovics40, Xavier Mariette45,46, Ivan Padjen35, José M Pego-Reigosa47, Juanita Romero-Diaz26, Íñigo Rúa-Figueroa Fernández48, Raphaèle Seror36, Georg H Stummvoll49, Yoshiya Tanaka50, Maria G Tektonidou51, Carlos Vasconcelos52, Edward M Vital53,54, Daniel J Wallace55, Sule Yavuz56, Pier Luigi Meroni57, Marvin J Fritzler58, Ray Naden59, Thomas Dörner18, Sindhu R Johnson60,61.   

Abstract

OBJECTIVE: To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
METHODS: This international initiative had four phases. (1) Evaluation of antinuclear antibody (ANA) as an entry criterion through systematic review and meta-regression of the literature and criteria generation through an international Delphi exercise, an early patient cohort and a patient survey. (2) Criteria reduction by Delphi and nominal group technique exercises. (3) Criteria definition and weighting based on criterion performance and on results of a multi-criteria decision analysis. (4) Refinement of weights and threshold scores in a new derivation cohort of 1001 subjects and validation compared with previous criteria in a new validation cohort of 1270 subjects.
RESULTS: The 2019 EULAR/ACR classification criteria for SLE include positive ANA at least once as obligatory entry criterion; followed by additive weighted criteria grouped in seven clinical (constitutional, haematological, neuropsychiatric, mucocutaneous, serosal, musculoskeletal, renal) and three immunological (antiphospholipid antibodies, complement proteins, SLE-specific antibodies) domains, and weighted from 2 to 10. Patients accumulating ≥10 points are classified. In the validation cohort, the new criteria had a sensitivity of 96.1% and specificity of 93.4%, compared with 82.8% sensitivity and 93.4% specificity of the ACR 1997 and 96.7% sensitivity and 83.7% specificity of the Systemic Lupus International Collaborating Clinics 2012 criteria.
CONCLUSION: These new classification criteria were developed using rigorous methodology with multidisciplinary and international input, and have excellent sensitivity and specificity. Use of ANA entry criterion, hierarchically clustered and weighted criteria reflect current thinking about SLE and provide an improved foundation for SLE research. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  classification criteria; consensus methods; lupus; multi-criteria decision analysis; systemic lupus erythematosus; validation

Mesh:

Year:  2019        PMID: 31383717     DOI: 10.1136/annrheumdis-2018-214819

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   27.973


  153 in total

1.  Renal thrombotic microangiopathy associated to worse renal prognosis in Lupus Nephritis.

Authors:  Fernando Louzada Strufaldi; Precil Diego Miranda de Menezes Menezes Neves; Cristiane Bitencourt Dias; Luis Yu; Viktoria Woronik; Livia Barreira Cavalcante; Denise Maria Avancini Costa Malheiros; Lectícia Barbosa Jorge
Journal:  J Nephrol       Date:  2021-02-11       Impact factor: 3.902

2.  Longitudinal anti-nuclear antibody (ANA) seroconversion in systemic lupus erythematosus: a prospective study of Swedish cases with recent-onset disease.

Authors:  M Frodlund; J Wetterö; C Dahle; Ö Dahlström; T Skogh; J Rönnelid; C Sjöwall
Journal:  Clin Exp Immunol       Date:  2019-12-19       Impact factor: 4.330

3.  Longitudinal growth patterns and final height in childhood-onset systemic lupus erythematosus.

Authors:  Pondtip Jongvilaikasem; Pornpimol Rianthavorn
Journal:  Eur J Pediatr       Date:  2021-01-03       Impact factor: 3.183

Review 4.  Cutaneous Lupus Erythematosus: Progress and Challenges.

Authors:  Amy J Petty; Lauren Floyd; Christopher Henderson; Matilda W Nicholas
Journal:  Curr Allergy Asthma Rep       Date:  2020-04-04       Impact factor: 4.806

5.  Multicentric study comparing cyclosporine, mycophenolate mofetil and azathioprine in the maintenance therapy of lupus nephritis: 8 years follow up.

Authors:  Lorenza Maria Argolini; Giulia Frontini; Elena Elefante; Francesca Saccon; Valentina Binda; Chiara Tani; Isabella Scotti; Linda Carli; Mariele Gatto; Ciro Esposito; Maria Gerosa; Roberto Caporali; Andrea Doria; Piergiorgio Messa; Marta Mosca; Gabriella Moroni
Journal:  J Nephrol       Date:  2020-05-27       Impact factor: 3.902

6.  Diffusion tensor imaging of renal cortex in lupus nephritis.

Authors:  Ahmed Abdel Khalek Abdel Razek; Ahmed Mohamed Abdel Khalek; Samar Tharwat; Mohammed Kamal Nassar; Nihal Tharwat
Journal:  Jpn J Radiol       Date:  2021-06-14       Impact factor: 2.374

7.  New classification criteria for systemic lupus erythematosus.

Authors:  Martin Aringer; Michelle Petri
Journal:  Curr Opin Rheumatol       Date:  2020-11       Impact factor: 5.006

Review 8.  Management of Severe Refractory Systemic Lupus Erythematosus: Real-World Experience and Literature Review.

Authors:  Huaxia Yang; Huazhen Liu; Ziyue Zhou; Lidan Zhao; Yunyun Fei; Hua Chen; Fengchun Zhang; Xuan Zhang
Journal:  Clin Rev Allergy Immunol       Date:  2020-11-07       Impact factor: 8.667

Review 9.  Lupus nephritis.

Authors:  Hans-Joachim Anders; Ramesh Saxena; Ming-Hui Zhao; Ioannis Parodis; Jane E Salmon; Chandra Mohan
Journal:  Nat Rev Dis Primers       Date:  2020-01-23       Impact factor: 52.329

10.  Macrophage activation syndrome as an initial presentation of systemic lupus erythematosus with sensorineural hearing loss in a young male patient.

Authors:  Chou Luan Tan; Muhammad Hafizuddin Yahaya; Noor Shahrazat Ahmad; Chong Hong Lim
Journal:  BMJ Case Rep       Date:  2020-03-12
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