| Literature DB >> 3137632 |
E Souêtre1, E Salvati, J L Belugou, P Robert, G Brunet, G Darcourt.
Abstract
5-Methoxypsoralen (5 MOP) administered daily (40 mg at 9 p.m.) was compared with placebo in the treatment of severe depression. The clinical response was evaluated using the Hamilton Depression Rating Scale after 1 week of treatment. Our preliminary data indicate that patients receiving 5 MOP improved significantly after 1 week, whereas patients treated with placebo did not. The stimulating effect of 5 MOP on the melatonin secretion may be involved in this clinical effect.Entities:
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Year: 1988 PMID： 3137632 DOI： 10.1007/bf00181962
Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530