| Literature DB >> 6823571 |
J Redman, S Armstrong, K T Ng.
Abstract
The pineal gland hormone melatonin may play a role in synchronization of rat circadian rhythms. Free-running activity rhythms of the rat were entrained by a daily melatonin injection, with entrainment occurring when the onset of activity coincided with the time of daily injections. When injections were stopped, activity rhythms became free-running again. Thus in pharmacological experiments, the time of day of melatonin administration is crucial.Entities:
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Year: 1983 PMID: 6823571 DOI: 10.1126/science.6823571
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728