Kelsey Roelofs1, Ezekiel Weis1,2. 1. Department of Ophthalmology and Visual Sciences, University of Alberta, Edmonton, Alberta, Canada. 2. Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Abstract
BACKGROUND/AIMS: To evaluate teleophthalmological assessment of choroidal and iris nevi (tele-oncology) compared to traditional in-person clinical evaluation for detection of either axial or basal growth. METHODS: This is a validation study. All 97 eyes of 99 patients were evaluated with an in-person ocular oncology visit utilizing standard testing, and subsequently had a tele-oncology evaluation with the standardized tests. The tele-oncology reviewer was blinded to the in-person examination findings. The primary study outcome was detection of nevus growth on tele-oncology compared to in-person clinical examination. RESULTS: Patients had a mean age of 61 years and the majority had nevi located in the choroid (n = 87; 88%). The most common diagnosis was a low-risk nevus (n = 38; 44%). By tele-oncology assessment, 11 eyes showed growth. Ten of these patients had growth confirmed on in-person clinical examination. Resultantly, tele-oncology assessment of choroidal and iris nevi growth had a sensitivity of 100%, specificity of 99%, positive predictive value (PPV) of 91%, and negative predictive value (NPV) of 100%. CONCLUSIONS: The results of this study suggest that tele-oncology is a safe platform for monitoring choroidal and iris nevi for growth, with excellent sensitivity, specificity, PPV, and NPV.
BACKGROUND/AIMS: To evaluate teleophthalmological assessment of choroidal and iris nevi (tele-oncology) compared to traditional in-person clinical evaluation for detection of either axial or basal growth. METHODS: This is a validation study. All 97 eyes of 99 patients were evaluated with an in-person ocular oncology visit utilizing standard testing, and subsequently had a tele-oncology evaluation with the standardized tests. The tele-oncology reviewer was blinded to the in-person examination findings. The primary study outcome was detection of nevus growth on tele-oncology compared to in-person clinical examination. RESULTS: Patients had a mean age of 61 years and the majority had nevi located in the choroid (n = 87; 88%). The most common diagnosis was a low-risk nevus (n = 38; 44%). By tele-oncology assessment, 11 eyes showed growth. Ten of these patients had growth confirmed on in-person clinical examination. Resultantly, tele-oncology assessment of choroidal and iris nevi growth had a sensitivity of 100%, specificity of 99%, positive predictive value (PPV) of 91%, and negative predictive value (NPV) of 100%. CONCLUSIONS: The results of this study suggest that tele-oncology is a safe platform for monitoring choroidal and iris nevi for growth, with excellent sensitivity, specificity, PPV, and NPV.
Authors: Max B Greenstein; Chelsea E Myers; Stacy M Meuer; Barbara E K Klein; Mary Frances Cotch; Tien Y Wong; Ronald Klein Journal: Ophthalmology Date: 2011-08-04 Impact factor: 12.079
Authors: Carol L Shields; Minoru Furuta; Archana Thangappan; Saya Nagori; Arman Mashayekhi; David R Lally; Cecilia C Kelly; Danielle S Rudich; Anand V Nagori; Oojwala A Wakade; Sonul Mehta; Lauren Forte; Andrew Long; Elaina F Dellacava; Bonnie Kaplan; Jerry A Shields Journal: Arch Ophthalmol Date: 2009-08
Authors: Carol L Shields; Minoru Furuta; Edwina L Berman; Jonathan D Zahler; Daniel M Hoberman; Diep H Dinh; Arman Mashayekhi; Jerry A Shields Journal: Arch Ophthalmol Date: 2009-08
Authors: Kelsey A Roelofs; Roderick O'Day; Lamis Al Harby; Amit K Arora; Victoria M L Cohen; Mandeep S Sagoo; Bertil Damato Journal: Cancers (Basel) Date: 2020-05-21 Impact factor: 6.639