OBJECTIVE: To describe the prevalence and characteristics of choroidal nevi in an Asian population and compare this with findings from a white population. METHODS: The Singapore Malay Eye Study (SiMES) examined a population-based, cross-sectional, age-stratified, random sample of 3280 Malay persons (78.7% participation rate) aged 40 to 80 years living in Singapore. Comprehensive examination of participants included bilateral retinal photography. Choroidal nevi were graded from photographs using the Blue Mountains Eye Study (BMES) protocol. RESULTS: The person-specific prevalence of choroidal nevi was 1.4%, with 50 nevi found in 45 participants. This is lower than the 6.5% prevalence seen in white persons in the BMES. However, characteristics of nevi in Malay persons in the SiMES were similar to those of white persons in the BMES by size (SiMES, 1.27 mm; BMES, 1.25 mm; P = .35), shape (P = .58), color (P = .39), location within posterior pole or periphery (P = .30), and nevus margin proximity to the optic disc (P = .29). Features previously identified as indicating growth or malignant potential (including diameter >6 mm, posterior margin touching optic disc, orange pigment, pigment clumping, and retinal edema) were not found in this sample. CONCLUSION: Choroidal nevi were detected in 1.4% of Malay persons. There were no significant racial or ethnic differences in nevi characteristics between Malay and white persons.
OBJECTIVE: To describe the prevalence and characteristics of choroidal nevi in an Asian population and compare this with findings from a white population. METHODS: The Singapore Malay Eye Study (SiMES) examined a population-based, cross-sectional, age-stratified, random sample of 3280 Malay persons (78.7% participation rate) aged 40 to 80 years living in Singapore. Comprehensive examination of participants included bilateral retinal photography. Choroidal nevi were graded from photographs using the Blue Mountains Eye Study (BMES) protocol. RESULTS: The person-specific prevalence of choroidal nevi was 1.4%, with 50 nevi found in 45 participants. This is lower than the 6.5% prevalence seen in white persons in the BMES. However, characteristics of nevi in Malay persons in the SiMES were similar to those of white persons in the BMES by size (SiMES, 1.27 mm; BMES, 1.25 mm; P = .35), shape (P = .58), color (P = .39), location within posterior pole or periphery (P = .30), and nevus margin proximity to the optic disc (P = .29). Features previously identified as indicating growth or malignant potential (including diameter >6 mm, posterior margin touching optic disc, orange pigment, pigment clumping, and retinal edema) were not found in this sample. CONCLUSION: Choroidal nevi were detected in 1.4% of Malay persons. There were no significant racial or ethnic differences in nevi characteristics between Malay and white persons.
Authors: Max B Greenstein; Chelsea E Myers; Stacy M Meuer; Barbara E K Klein; Mary Frances Cotch; Tien Y Wong; Ronald Klein Journal: Ophthalmology Date: 2011-08-04 Impact factor: 12.079
Authors: Carol L Shields; Janet Manalac; Chandana Das; Jarin Saktanasate; Jerry A Shields Journal: Indian J Ophthalmol Date: 2015-02 Impact factor: 1.848
Authors: Carol L Shields; Sara E Lally; Lauren A Dalvin; Mandeep S Sagoo; Marco Pellegrini; Swathi Kaliki; Ahmet Kaan Gündüz; Minoru Furuta; Prithvi Mruthyunjaya; Adrian T Fung; Jay S Duker; Sara M Selig; Antonio Yaghy; Sandor R Ferenczy; Malvina B Eydelman; Mark S Blumenkranz Journal: Transl Vis Sci Technol Date: 2021-02-05 Impact factor: 3.283
Authors: Charlotte L Marous; Carol L Shields; Michael D Yu; Lauren A Dalvin; David Ancona-Lezama; Jerry A Shields Journal: Indian J Ophthalmol Date: 2019-12 Impact factor: 1.848