Literature DB >> 31364861

Monocyte to high-density lipoprotein cholesterol ratio predicts adverse cardiac events in patients with hypertrophic cardiomyopathy.

Firdevs Aysenur Ekizler1, Serkan Cay1, Burak Açar2, Bahar Tekin Tak1, Habibe Kafes1, Ozcan Ozeke1, Elif Hande Ozcan Cetin1, Firat Ozcan1, Serkan Topaloglu1, Omac Tufekcioglu1, Dursun Aras1.   

Abstract

Aim: The aim of the study was to investigate the monocyte count to HDL cholesterol ratio (MHR) on the prognosis of patients with hypertrophic cardiomyopathy (HCM). Materials & methods: A total of 411 patients with HCM were assessed. The primary end point was cardiovascular death or malignant arrhythmic events.
Results: During the follow-up, primary end point was developed in 54 (13.1%) patients. Receiver operating characteristic (ROC) analysis showed that using a cut-off level of 14.57, MHR predicted the occurrence of primary end point with a sensitivity of 72% and specificity of 72%. In the multivariate model, high MHR was the only significant predictor of the primary end point.
Conclusion: This study showed that higher MHR level is an independent predictor of malignant arrhythmia and death in patients with HCM.

Entities:  

Keywords:  adverse outcomes; arrhythmia; cardiovascular death; hypertrophic cardiomyopathy; inflammation; monocyte to HDL cholesterol ratio; prognosis; risk stratification

Mesh:

Substances:

Year:  2019        PMID: 31364861     DOI: 10.2217/bmm-2019-0089

Source DB:  PubMed          Journal:  Biomark Med        ISSN: 1752-0363            Impact factor:   2.851


  6 in total

1.  Monocyte to high-density lipoprotein cholesterol ratio as an independent risk factor for papillary thyroid carcinoma.

Authors:  Hongzhi Xu; Yufeng Pang; Xueqing Li; Bingbing Zha; Tao He; Heyuan Ding
Journal:  J Clin Lab Anal       Date:  2021-09-21       Impact factor: 2.352

2.  Value of the Systemic Immune-Inflammatory Index (SII) in Predicting the Prognosis of Patients With Peripartum Cardiomyopathy.

Authors:  Yuan Zhang; Wenzhao Liu; Huaitao Yu; Zhen Chen; Chunmei Zhang; Yun Ti; Peili Bu
Journal:  Front Cardiovasc Med       Date:  2022-02-17

3.  Relation between lymphocyte to monocyte ratio and survival in patients with hypertrophic cardiomyopathy: a retrospective cohort study.

Authors:  Zhonglan Chen; Ziqiong Wang; Youping Li; Xiaoping Chen; Sen He
Journal:  PeerJ       Date:  2022-03-29       Impact factor: 2.984

4.  Assessing the relationship between systemic immune-inflammation index and mortality in patients with hypertrophic cardiomyopathy.

Authors:  Ziqiong Wang; Haiyan Ruan; Liying Li; Xin Wei; Ye Zhu; Jiafu Wei; Xiaoping Chen; Sen He
Journal:  Ups J Med Sci       Date:  2021-12-03       Impact factor: 2.384

5.  Fragmented QRS as a candidate marker for left ventricular nonrecovery in patients with peripartum cardiomyopathy.

Authors:  Bahar Tekin Tak; Serkan Cay; Firdevs Aysenur Ekizler; Elif Hande Ozcan Cetin; Hilal Erken Pamukcu; Habibe Kafes; Nedret Ulvan; Ozcan Ozeke; Firat Ozcan; Serkan Topaloglu; Dursun Aras
Journal:  Ann Noninvasive Electrocardiol       Date:  2019-10-06       Impact factor: 1.468

6.  N-terminal pro-brain natriuretic peptide and adverse outcomes in Chinese patients with hypertrophic cardiomyopathy.

Authors:  Zeng-Lei Zhang; Yan-Yan Xu; Zhen Qin; Yong-Zheng Lu; Tian-Ding Liu; Li Zhang; Jia-Hong Shangguan; Wei Wang; Jun-Nan Tang; Jin-Ying Zhang
Journal:  Biosci Rep       Date:  2022-01-28       Impact factor: 3.840

  6 in total

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