Literature DB >> 31346367

Prevalence and Economic Burden of Epilepsy in the Institutionalized Medicare Fee-for-Service Population.

Kathryn Fitch1, Xiaoyun Pan2, Jocelyn Lau3, Tyler Engel4, Krithika Rajagopalan5.   

Abstract

BACKGROUND: Based on data from 2003 to 2007, the prevalence of epilepsy was significantly higher in the institutionalized elderly population than in the noninstitutionalized population, but the recent prevalence and economic impact of epilepsy specifically in the institutionalized Medicare population have not been reported.
OBJECTIVES: To estimate the prevalence and economic burden of epilepsy and inpatient utilization rates among institutionalized Medicare beneficiaries and to provide a 10-year projection of their population size and the associated costs.
METHODS: We performed a cross-sectional analysis of the institutionalized Medicare population with and without epilepsy using Medicare 5% sample claims data from 2013 and 2014. The identification of epilepsy required ≥1 qualifying claims with an epilepsy diagnosis, or ≥2 qualifying claims ≥30 days apart with a diagnosis of convulsion, in 2014. Institutionalized status was identified by having ≥6 consecutive months of nursing facility claims in 2013 or 2014. Inpatient admissions and 30-day readmissions, average allowed costs, and risk-adjusted incremental costs of epilepsy were calculated and compared between the institutionalized population of Medicare beneficiaries with and without epilepsy. The 2015 Medicare 100% and 5% sample data and inputs from other external sources were used to project the 10-year trends in the size and cost of the institutionalized Medicare population with epilepsy.
RESULTS: The prevalence of epilepsy in 2014 was 11.1% in the institutionalized Medicare population. The institutionalized population with epilepsy had significantly higher per-patient per-month (PPPM) costs ($3479 vs $2381, respectively; P <.001), inpatient admissions per 1000 beneficiaries (1105 vs 697, respectively; P <.001), and 30-day readmissions per 1000 beneficiaries (287 vs 145, respectively; P <.001) versus the institutionalized population without epilepsy. The risk-adjusted incremental cost of epilepsy for the institutionalized population was $507.33 PPPM. Based on our model, between 2017 and 2027 an 18% increase in size and a 72% increase in cost are projected for the institutionalized Medicare beneficiaries with epilepsy.
CONCLUSION: The high cost and inpatient resource utilization, as well as the projected growth of the institutionalized Medicare population with epilepsy highlight the need for further investigation of care management opportunities to reduce the cost burden associated with this condition.

Entities:  

Keywords:  Medicare fee for service; epilepsy; healthcare utilization; inpatient admissions; institutionalized elderly population

Year:  2019        PMID: 31346367      PMCID: PMC6611517     

Source DB:  PubMed          Journal:  Am Health Drug Benefits        ISSN: 1942-2962


  20 in total

1.  Economic burden of epilepsy among the privately insured in the US.

Authors:  Jasmina I Ivanova; Howard G Birnbaum; Yohanne Kidolezi; Ying Qiu; David Mallett; Sue Caleo
Journal:  Pharmacoeconomics       Date:  2010       Impact factor: 4.981

2.  Health plan paid cost of epilepsy in 2009 in the U.S.

Authors:  Andrew N Wilner; Bal K Sharma; Alison Soucy; Andrew Krueger
Journal:  Epilepsy Behav       Date:  2012-11-01       Impact factor: 2.937

3.  Incidence and prevalence of epilepsy among older U.S. Medicare beneficiaries.

Authors:  E Faught; J Richman; R Martin; E Funkhouser; R Foushee; P Kratt; Y Kim; K Clements; N Cohen; D Adoboe; R Knowlton; M Pisu
Journal:  Neurology       Date:  2012-01-18       Impact factor: 9.910

4.  The cost of epilepsy in the United States: an estimate from population-based clinical and survey data.

Authors:  C E Begley; M Famulari; J F Annegers; D R Lairson; T F Reynolds; S Coan; S Dubinsky; M E Newmark; C Leibson; E L So; W A Rocca
Journal:  Epilepsia       Date:  2000-03       Impact factor: 5.864

5.  Treatment of epilepsy in the elderly.

Authors:  Ilo E Leppik
Journal:  Curr Treat Options Neurol       Date:  2008-07       Impact factor: 3.598

Review 6.  Poststroke seizures in the elderly.

Authors:  J J Asconapé; J K Penry
Journal:  Clin Geriatr Med       Date:  1991-08       Impact factor: 3.076

7.  Prevalence and cost of nonadherence to antiepileptic drugs in elderly patients with epilepsy.

Authors:  Alan B Ettinger; Ranjani Manjunath; Sean D Candrilli; Keith L Davis
Journal:  Epilepsy Behav       Date:  2008-11-24       Impact factor: 2.937

8.  The burden of epilepsy to patients and payers.

Authors:  William J Cardarelli; Brien J Smith
Journal:  Am J Manag Care       Date:  2010-12       Impact factor: 2.229

9.  Inpatient charges and mental illness: Findings from the Nationwide Inpatient Sample 1999-2007.

Authors:  Jim E Banta; Ivorie Belk; Kedon Newton; Abdullah Sherzai
Journal:  Clinicoecon Outcomes Res       Date:  2010-10-11

10.  Management of epilepsy in the elderly.

Authors:  Juan José Poza
Journal:  Neuropsychiatr Dis Treat       Date:  2007-12       Impact factor: 2.570

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  2 in total

1.  The neurophysiology and seizure outcomes of late onset unexplained epilepsy.

Authors:  Rani A Sarkis; Louis Beers; Emile Farah; Mohammad Al-Akaidi; Yuxiang Zhang; Joseph J Locascio; Michael J Properzi; Aaron P Schultz; Jasmeer P Chhatwal; Keith A Johnson; Reisa A Sperling; Page B Pennell; Gad A Marshall
Journal:  Clin Neurophysiol       Date:  2020-09-19       Impact factor: 3.708

2.  Healthcare Resource Utilization Among Patients with Focal Seizures Treated with Eslicarbazepine Acetate in the US Long-Term Care Setting: A Retrospective Claims Database Analysis.

Authors:  Darshan Mehta; Drishti Shah; Vibha Desai; Mitch DeKoven; Ronald DePue; G Rhys Williams; Dana Saffel
Journal:  Neurol Ther       Date:  2021-04-07
  2 in total

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