Literature DB >> 22262750

Incidence and prevalence of epilepsy among older U.S. Medicare beneficiaries.

E Faught1, J Richman, R Martin, E Funkhouser, R Foushee, P Kratt, Y Kim, K Clements, N Cohen, D Adoboe, R Knowlton, M Pisu.   

Abstract

OBJECTIVE: To determine the prevalence and incidence of epilepsy among U.S. Medicare beneficiaries aged 65 years old and over, and to compare rates across demographic groups.
METHODS: We performed a retrospective analysis of Medicare administrative claims for 2001-2005, defining prevalent cases as persons with ≥1 claim with diagnosis code 345.xx (epilepsy) or 2 or more with diagnosis code 780.3x (convulsion) ≥1 month apart, and incident cases as prevalent cases with 2 years immediately before diagnosis without such claims. Prevalence and incidence rates were calculated for the years 2003-2005 using denominators estimated from a 5% random sample of Medicare beneficiaries. Results were correlated with gender, age, and race.
RESULTS: We identified 282,661 per year on average during 2001-2005 (a total of 704,243 unique cases overall), and 62,182 incident cases per year on average during 2003-2005. Average annual prevalence and incidence rates were 10.8/1,000 and 2.4/1,000. Overall, rates were higher for black beneficiaries (prevalence 18.7/1,000, incidence 4.1/1,000), and lower for Asians (5.5/1,000, 1.6/1,000) and Native Americans (7.7/1,000, 1.1/1,000) than for white beneficiaries (10.2/1,000, 2.3/1,000). Incidence rates were slightly higher for women than for men, and increased with age for all gender and race groups.
CONCLUSIONS: Epilepsy is a significant public health problem among Medicare beneficiaries. Efforts are necessary to target groups at higher risk, such as minorities or the very old, and to provide the care necessary to reduce the negative effects of epilepsy on quality of life.

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Year:  2012        PMID: 22262750      PMCID: PMC3280050          DOI: 10.1212/WNL.0b013e3182477edc

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  22 in total

Review 1.  Growing old with epilepsy: the neglected issue of cognitive and brain health in aging and elder persons with chronic epilepsy.

Authors:  Bruce Hermann; Michael Seidenberg; Mark Sager; Cynthia Carlsson; Barry Gidal; Raj Sheth; Paul Rutecki; Sanjay Asthana
Journal:  Epilepsia       Date:  2007-11-21       Impact factor: 5.864

2.  Incidence of epilepsy in a racially diverse, community-dwelling, elderly cohort: results from the Einstein aging study.

Authors:  S A Hussain; S R Haut; R B Lipton; C Derby; S Y Markowitz; S Shinnar
Journal:  Epilepsy Res       Date:  2006-07-25       Impact factor: 3.045

3.  Developing a computer algorithm to identify epilepsy cases in managed care organizations.

Authors:  E Wayne Holden; Elizabeth Grossman; Hoang Thanh Nguyen; Margaret J Gunter; Becky Grebosky; Ann Von Worley; Leila Nelson; Scott Robinson; David J Thurman
Journal:  Dis Manag       Date:  2005-02

Review 4.  Poststroke seizures.

Authors:  Isaac E Silverman; Lucas Restrepo; Gregory C Mathews
Journal:  Arch Neurol       Date:  2002-02

5.  The incidence of epilepsy and unprovoked seizures in multiethnic, urban health maintenance organizations.

Authors:  J F Annegers; S Dubinsky; S P Coan; M E Newmark; L Roht
Journal:  Epilepsia       Date:  1999-04       Impact factor: 5.864

6.  Estimating prevalence, incidence, and disease-related mortality for patients with epilepsy in managed care organizations.

Authors:  E Wayne Holden; Hoang Thanh Nguyen; Elizabeth Grossman; Scott Robinson; Leila S Nelson; Margaret J Gunter; Ann Von Worley; David J Thurman
Journal:  Epilepsia       Date:  2005-02       Impact factor: 5.864

7.  How common are the "common" neurologic disorders?

Authors:  D Hirtz; D J Thurman; K Gwinn-Hardy; M Mohamed; A R Chaudhuri; R Zalutsky
Journal:  Neurology       Date:  2007-01-30       Impact factor: 9.910

Review 8.  Descriptive epidemiology of epilepsy: contributions of population-based studies from Rochester, Minnesota.

Authors:  W A Hauser; J F Annegers; W A Rocca
Journal:  Mayo Clin Proc       Date:  1996-06       Impact factor: 7.616

9.  Prevalence of epilepsy and seizures in the Navajo Nation 1998-2002.

Authors:  Karen Parko; David J Thurman
Journal:  Epilepsia       Date:  2009-06-01       Impact factor: 5.864

10.  Incidence and clinical characterization of unprovoked seizures in adults: a prospective population-based study.

Authors:  L Forsgren; G Bucht; S Eriksson; L Bergmark
Journal:  Epilepsia       Date:  1996-03       Impact factor: 5.864

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  49 in total

1.  Late-onset epilepsy and 25-year cognitive change: The Atherosclerosis Risk in Communities (ARIC) study.

Authors:  Emily L Johnson; Gregory L Krauss; Keenan A Walker; Jason Brandt; Anna Kucharska-Newton; Thomas H Mosley; Sevil Yasar; Rebecca F Gottesman
Journal:  Epilepsia       Date:  2020-07-24       Impact factor: 5.864

2.  Disparities in access to specialized epilepsy care.

Authors:  Nicholas K Schiltz; Siran M Koroukian; Mendel E Singer; Thomas E Love; Kitti Kaiboriboon
Journal:  Epilepsy Res       Date:  2013-08-16       Impact factor: 3.045

3.  Accuracy of claims-based algorithms for epilepsy research: Revealing the unseen performance of claims-based studies.

Authors:  Lidia M V R Moura; Maggie Price; Andrew J Cole; Daniel B Hoch; John Hsu
Journal:  Epilepsia       Date:  2017-02-15       Impact factor: 5.864

Review 4.  Risk of falls associated with antiepileptic drug use in ambulatory elderly populations: A systematic review.

Authors:  Mira Maximos; Feng Chang; Tejal Patel
Journal:  Can Pharm J (Ott)       Date:  2017-03-01

5.  cEEG electrode-related pressure ulcers in acutely hospitalized patients.

Authors:  Lidia M V R Moura; Thiago S Carneiro; David Kwasnik; Valdery F Moura; Christine S Blodgett; Joseph Cohen; Mary McKenna Guanci; Daniel B Hoch; John Hsu; Andrew J Cole; M Brandon Westover
Journal:  Neurol Clin Pract       Date:  2017-02

6.  Identification of prevalent patients with epilepsy using administrative data: the Tuscany experience.

Authors:  Irene Bellini; Laura Policardo; Gaetano Zaccara; Pasquale Palumbo; Eleonora Rosati; Elena Torre; Paolo Francesconi
Journal:  Neurol Sci       Date:  2017-01-04       Impact factor: 3.307

7.  Epilepsy Among Elderly Medicare Beneficiaries: A Validated Approach to Identify Prevalent and Incident Epilepsy.

Authors:  Lidia M V R Moura; Jason R Smith; Deborah Blacker; Christine Vogeli; Lee H Schwamm; Andrew J Cole; Sonia Hernandez-Diaz; John Hsu
Journal:  Med Care       Date:  2019-04       Impact factor: 2.983

8.  Depression and quality of life among African Americans with epilepsy: Findings from the Managing Epilepsy Well (MEW) Network integrated database.

Authors:  Robin E McGee; Martha Sajatovic; Rakale C Quarells; Erika K Johnson; Hongyan Liu; Tanya M Spruill; Robert T Fraser; Mary Janevic; Cam Escoffery; Nancy J Thompson
Journal:  Epilepsy Behav       Date:  2019-04-08       Impact factor: 2.937

9.  Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study.

Authors:  Emily L Johnson; Gregory L Krauss; Alexandra K Lee; Andrea L C Schneider; Jennifer L Dearborn; Anna M Kucharska-Newton; Juebin Huang; Alvaro Alonso; Rebecca F Gottesman
Journal:  JAMA Neurol       Date:  2018-11-01       Impact factor: 18.302

10.  Quality of Antiepileptic Treatment Among Older Medicare Beneficiaries With Epilepsy: A Retrospective Claims Data Analysis.

Authors:  Maria Pisu; Joshua Richman; Kendra Piper; Roy Martin; Ellen Funkhouser; Chen Dai; Lucia Juarez; Jerzy P Szaflarski; Edward Faught
Journal:  Med Care       Date:  2017-07       Impact factor: 2.983

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