| Literature DB >> 31344665 |
Kai-Lun Hu1, Hongcui Zhao2, Yang Yu2, Rong Li3.
Abstract
Kisspeptins are a family of neuropeptides that are critical for the puberty initiation and female fertility. Plasma or serum kisspeptin is mainly derived from the placenta during pregnancy and plasma kisspeptin levels significantly increase across pregnancy. Plasma kisspeptin levels could be used as a potential biomarker for the detection of miscarriage, pre-eclampsia, gestational trophoblastic neoplasia (GTN), and fetal development. Kisspeptin may also be involved in the process of parturition by stimulating oxytocin secretion during term pregnancy. This review discussed the potential use of kisspeptin as a marker across pregnancy and highlighted the unresolved problems in this area. Tweetable abstract: Plasma kisspeptin levels could be used as a potential biomarker across pregnancy.Entities:
Keywords: Kisspeptin; Miscarriage; Placenta; Pre-eclampsia; Pregnancy
Mesh:
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Year: 2019 PMID: 31344665 DOI: 10.1016/j.ejogrb.2019.07.016
Source DB: PubMed Journal: Eur J Obstet Gynecol Reprod Biol ISSN: 0301-2115 Impact factor: 2.435