| Literature DB >> 31336199 |
Shria Kumar1, David C Metz2, David E Kaplan3, David S Goldberg2.
Abstract
Conventional teaching is that Helicobacter pylori infection is required for the development of non-cardia gastric adenocarcinoma (NCGC) through a sequence of atrophic gastritis, intestinal metaplasia, dysplasia, and finally, cancer.1-3 However, studies have not demonstrated a 100% rate of H pylori infection in gastric malignancy, hypothesized to be due to false negatives, gastric atrophy leading to apparent loss of infection, and inclusion of cardia, nonintestinal cancers.1-3.Entities:
Year: 2019 PMID: 31336199 PMCID: PMC6980451 DOI: 10.1016/j.cgh.2019.07.026
Source DB: PubMed Journal: Clin Gastroenterol Hepatol ISSN: 1542-3565 Impact factor: 11.382