Literature DB >> 31317359

Minimizing off-target effects in CRISPR-Cas9 genome editing.

Shi-Jie Chen1.   

Abstract

Entities:  

Year:  2019        PMID： 31317359      PMCID： PMC6883159          DOI： 10.1007/s10565-019-09486-4

Source DB:  PubMed          Journal:  Cell Biol Toxicol        ISSN： 0742-2091            Impact factor:   6.691


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  12 in total

1.  Unified energetics analysis unravels SpCas9 cleavage activity for optimal gRNA design.

Authors:  Dong Zhang; Travis Hurst; Dongsheng Duan; Shi-Jie Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2019-04-15       Impact factor: 11.205

2.  Off-target genome editing: A new discipline of gene science and a new class of medicine.

Authors:  Diane Catherine Wang; Xiangdong Wang
Journal:  Cell Biol Toxicol       Date:  2019-04-27       Impact factor: 6.691

3.  Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

Authors:  Bin Shen; Wensheng Zhang; Jun Zhang; Jiankui Zhou; Jianying Wang; Li Chen; Lu Wang; Alex Hodgkins; Vivek Iyer; Xingxu Huang; William C Skarnes
Journal:  Nat Methods       Date:  2014-03-02       Impact factor: 28.547

4.  Rationally engineered Cas9 nucleases with improved specificity.

Authors:  Ian M Slaymaker; Linyi Gao; Bernd Zetsche; David A Scott; Winston X Yan; Feng Zhang
Journal:  Science       Date:  2015-12-01       Impact factor: 47.728

5.  CRISPR-Cas9 cleavage efficiency correlates strongly with target-sgRNA folding stability: from physical mechanism to off-target assessment.

Authors:  Xiaojun Xu; Dongsheng Duan; Shi-Jie Chen
Journal:  Sci Rep       Date:  2017-03-10       Impact factor: 4.379

6.  Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.

Authors:  Janice S Chen; Yavuz S Dagdas; Benjamin P Kleinstiver; Moira M Welch; Alexander A Sousa; Lucas B Harrington; Samuel H Sternberg; J Keith Joung; Ahmet Yildiz; Jennifer A Doudna
Journal:  Nature       Date:  2017-09-20       Impact factor: 49.962

7.  Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification.

Authors:  John P Guilinger; David B Thompson; David R Liu
Journal:  Nat Biotechnol       Date:  2014-04-25       Impact factor: 54.908

8.  Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.

Authors:  Yanfang Fu; Jeffry D Sander; Deepak Reyon; Vincent M Cascio; J Keith Joung
Journal:  Nat Biotechnol       Date:  2014-01-26       Impact factor: 54.908

9.  Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.

Authors:  Shengdar Q Tsai; Nicolas Wyvekens; Cyd Khayter; Jennifer A Foden; Vishal Thapar; Deepak Reyon; Mathew J Goodwin; Martin J Aryee; J Keith Joung
Journal:  Nat Biotechnol       Date:  2014-04-25       Impact factor: 54.908

10.  High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Authors:  Benjamin P Kleinstiver; Vikram Pattanayak; Michelle S Prew; Shengdar Q Tsai; Nhu T Nguyen; Zongli Zheng; J Keith Joung
Journal:  Nature       Date:  2016-01-06       Impact factor: 49.962
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  7 in total

1.  Functional inhibition of the StERF3 gene by dual targeting through CRISPR/Cas9 enhances resistance to the late blight disease in Solanum tuberosum L.

Authors:  Hafiza Arooj Razzaq; Siddra Ijaz; Imran Ul Haq; Iqrar Ahmad Khan
Journal:  Mol Biol Rep       Date:  2022-09-30       Impact factor: 2.742

Review 2.  Molecular mechanisms, off-target activities, and clinical potentials of genome editing systems.

Authors:  Nannan Zheng; Liyang Li; Xiangdong Wang
Journal:  Clin Transl Med       Date:  2020-01

Review 3.  CRISPR/Cas9-Mediated Gene Correction to Understand ALS.

Authors:  Yeomin Yun; Yoon Ha
Journal:  Int J Mol Sci       Date:  2020-05-27       Impact factor: 5.923

4.  CRISPR/Cas9 mediated mutagenesis of MORE AXILLARY GROWTH 1 in tomato confers resistance to root parasitic weed Phelipanche aegyptiaca.

Authors:  Vinay Kumar Bari; Jackline Abu Nassar; Radi Aly
Journal:  Sci Rep       Date:  2021-02-16       Impact factor: 4.379

Review 5.  Genome Editing for Sustainable Crop Improvement and Mitigation of Biotic and Abiotic Stresses.

Authors:  Mohd Fadhli Hamdan; Chou Khai Soong Karlson; Ee Yang Teoh; Su-Ee Lau; Boon Chin Tan
Journal:  Plants (Basel)       Date:  2022-10-06

Review 6.  Fine mapping and gene cloning in the post-NGS era: advances and prospects.

Authors:  Deepa Jaganathan; Abhishek Bohra; Mahendar Thudi; Rajeev K Varshney
Journal:  Theor Appl Genet       Date:  2020-02-10       Impact factor: 5.699

7.  Metabolic alterations in Parkinson's disease astrocytes.

Authors:  Tuuli-Maria Sonninen; Riikka H Hämäläinen; Marja Koskuvi; Minna Oksanen; Anastasia Shakirzyanova; Sara Wojciechowski; Katja Puttonen; Nikolay Naumenko; Gundars Goldsteins; Nihay Laham-Karam; Marko Lehtonen; Pasi Tavi; Jari Koistinaho; Šárka Lehtonen
Journal:  Sci Rep       Date:  2020-09-02       Impact factor: 4.379
  7 in total

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