Literature DB >> 31316256

Use of a biphasic cement bone substitute in the management of metaphyseal fractures.

Quan You Yeo1, Ernest Beng Kee Kwek1.   

Abstract

OBJECTIVES: In recent years, the increase in utilisation of bone substitutes in the reconstruction of bone defects has been fuelled by donor site complications associated with autologous bone harvesting. However the ability of bone substitute to stimulate bone union while maintaining fracture reduction has been a topic of debate. Cerament Bone Void Filler (CBVF) is a novel biphasic and injectable ceramic bone substitute that has high compressive strength and the ability to promote cancellous bone healing. MATERIALS AND
METHOD: This is a retrospective study to evaluate the surgical outcome of utilising CBVF in the treatment of depressed metaphyseal bone fractures over a two year period. The patients were followed up for at least six months after surgery and clinical parameters such as wound site complications were collated. Radiographic imaging was evaluated to determine loss of fracture reduction and rate of cement resorption.
RESULTS: Thirteen patients with depressed metaphyseal fractures were enrolled, which included: (i) one proximal humerus fracture; (ii) three tibial plateau fractures; and (iii) nine calcaneal fractures. None of the patients showed significant collapse in fracture reduction after six months of follow up. Cement resorption was noted in one patient as early as three weeks after surgery. There were no cases of cement leak or wound site complications.
CONCLUSION: Cerament Bone Void Filler (CBVF) is a promising bone graft substitute in the management of depressed metaphyseal bone fractures, with the ability to maintain fracture reduction despite cement resorption.

Entities:  

Keywords:  Bone cement; Cerament; Metaphyseal fracture

Year:  2018        PMID: 31316256      PMCID: PMC6611836          DOI: 10.1016/j.jcot.2018.08.014

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN: 0976-5662


  10 in total

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Journal:  J Bone Joint Surg Br       Date:  2001-01

2.  Bone healing using a bi-phasic ceramic bone substitute demonstrated in human vertebroplasty and with histology in a rabbit cancellous bone defect model.

Authors:  H P Hatten; M J Voor
Journal:  Interv Neuroradiol       Date:  2012-03-16       Impact factor: 1.610

3.  Bioceramic vertebral augmentation with a calcium sulphate/hydroxyapatite composite (Cerament SpineSupport): in vertebral compression fractures due to osteoporosis.

Authors:  Michael Rauschmann; Thomas Vogl; Akhil Verheyden; Robert Pflugmacher; Thomas Werba; Sven Schmidt; Johannes Hierholzer
Journal:  Eur Spine J       Date:  2010-02-04       Impact factor: 3.134

4.  Tibial plateau fracture repairs augmented with calcium phosphate cement have higher in situ fatigue strength than those with autograft.

Authors:  Erik McDonald; Thomas Chu; Michael Tufaga; Meir Marmor; Ravinder Singh; Duran Yetkinler; Amir Matityahu; Jenni M Buckley; R Trigg McClellan
Journal:  J Orthop Trauma       Date:  2011-02       Impact factor: 2.512

5.  Osteotomy of distal radius fracture malunion using a fast remodeling bone substitute consisting of calcium sulphate and calcium phosphate.

Authors:  Antonio Abramo; Mats Geijer; Philippe Kopylov; Magnus Tägil
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2010-01       Impact factor: 3.368

6.  Comparison of autogenous bone graft and endothermic calcium phosphate cement for defect augmentation in tibial plateau fractures. A multicenter, prospective, randomized study.

Authors:  Thomas A Russell; Ross K Leighton
Journal:  J Bone Joint Surg Am       Date:  2008-10       Impact factor: 5.284

7.  The use of calcium phosphate bone cement in fracture treatment. A meta-analysis of randomized trials.

Authors:  Sohail S Bajammal; Michael Zlowodzki; Amy Lelwica; Paul Tornetta; Thomas A Einhorn; Richard Buckley; Ross Leighton; Thomas A Russell; Sune Larsson; Mohit Bhandari
Journal:  J Bone Joint Surg Am       Date:  2008-06       Impact factor: 5.284

Review 8.  Surgical fixation methods for tibial plateau fractures.

Authors:  Iain R McNamara; Toby O Smith; Karen L Shepherd; Allan B Clark; Dominic M Nielsen; Simon Donell; Caroline B Hing
Journal:  Cochrane Database Syst Rev       Date:  2015-09-15

9.  Augmentation of tibial plateau fractures with an injectable bone substitute: CERAMENT™. Three year follow-up from a prospective study.

Authors:  Riccardo Iundusi; Elena Gasbarra; Michele D'Arienzo; Andrea Piccioli; Umberto Tarantino
Journal:  BMC Musculoskelet Disord       Date:  2015-05-13       Impact factor: 2.362

10.  CERAMENT treatment of fracture defects (CERTiFy): protocol for a prospective, multicenter, randomized study investigating the use of CERAMENT™ BONE VOID FILLER in tibial plateau fractures.

Authors:  Thomas Nusselt; Alexander Hofmann; Daniel Wachtlin; Stanislav Gorbulev; Pol Maria Rommens
Journal:  Trials       Date:  2014-03-08       Impact factor: 2.279

  10 in total
  2 in total

1.  Nanocrystalline hydroxyapatite-poly(thioketal urethane) nanocomposites stimulate a combined intramembranous and endochondral ossification response in rabbits.

Authors:  Madison A P McGough; Lauren A Boller; Dustin M Groff; Jonathan G Schoenecker; Jeffry S Nyman; Joseph C Wenke; Cheyenne Rhodes; Dan Shimko; Craig L Duvall; Scott A Guelcher
Journal:  ACS Biomater Sci Eng       Date:  2019-12-10

2.  Treatment of benign bone lesions with an injectable biphasic bone substitute.

Authors:  Kevin Döring; Colleen Rentenberger; Alexander Kolb; Janina Patsch; Stephan Puchner; Reinhard Windhager; Catharina Chiari
Journal:  BMC Musculoskelet Disord       Date:  2022-10-08       Impact factor: 2.562

  2 in total

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