| Literature DB >> 31313340 |
Hazel Parker1, Odran Farrell1, Rob Bethune2, Ali Hodgetts1, Karen Mattick3.
Abstract
AIMS: To develop and evaluate a feasible, authentic pharmacist-led prescribing feedback intervention for doctors-in-training, to reduce prescribing errors.Entities:
Keywords: clinical pharmacy; medical education; medication errors; patient safety; prescribing
Mesh:
Year: 2019 PMID: 31313340 PMCID: PMC6783579 DOI: 10.1111/bcp.14065
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN: 0306-5251 Impact factor: 4.335
Figure 1Statistical process chart showing pharmacist interventions per day (each equating to a prescribing error) over 18 months on the surgical admissions unit. The dates are given on the X‐axis. The test phase is shaded white and is when the initial pulse of the intervention was carried out. The baseline data, to the left of this, was collected before the project. The sustain phase, to the right of this, is when the remainder of the participants took part in the intervention. The horizontal lines in the baseline and sustain phases show the mean, with lines above and below this representing 1, 2 and 3 sigma from the mean. The 3 sigma from the mean lines are also called the upper and lower control limits. These statistics show that the mean has significantly reduced in the sustain phase and the variance (sigma) has also reduced, since the lines are closer together
Data showing the changes in pharmacist intervention rates and therefore prescribing errors, each reflected by a pharmacist intervention, at baseline and after the feedback intervention
| Baseline (over 50 days) | Project (over 23 days) | Percentage reduction | |
|---|---|---|---|
| Number of patients | 682 | 241 | ‐ |
| Number of pharmacist interventions | 950 | 269 | ‐ |
| Average pharmacist interventions per day | 19.0 | 11.7 | 38% |
| Average pharmacist interventions per patient | 1.39 | 1.12 | 20% |
Figure 2Weekly patient admissions data for the surgical admissions unit over the same time period as the statistical process chart in Figure 1, demonstrating an overall increasing trend (mean weekly admissions is 51.0 during the baseline period, 62.8 during the test period and 69.1 during the sustain period)
Examples of errors in the 4 different categories that were discovered and corrected during the project
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| • 83‐year‐old woman incorrectly prescribed 80 mg of bisoprolol (a relatively potent β‐blocker) once a day by an FY1 doctor. This should have been propranolol (a less potent β‐blocker). This was spotted and corrected by a pharmacist before it could be given to the patient. Giving such a high dose of bisoprolol would have resulted in profound bradycardia (slow pulse) with hypotension (low blood pressure) and could have led to serious cardiac conduction abnormalities, potential cardiac arrest and death. |
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| • 67‐year‐old man incorrectly prescribed Morphgesic (prolonged release morphine) 180 mg twice a day. This was spotted and corrected by a pharmacist before it could be given to the patient. Inappropriately high doses of opioids can lead to bradycardia, respiratory depression and hypotension requiring administration of an antidote. |
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| • 94‐year‐old man, with a history of atrial fibrillation, was prescribed apixaban 2.5 mg once a day. This should have been twice a day as per his drug history. This was corrected by the pharmacist. |
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| • 74‐year‐old man prescribed ondansetron 4–8 mg oral or intravenously when required as an antiemetic. However, no frequency or minimum dosing interval was specified. This was corrected by the pharmacist. |
Excerpts from semistructured interviews with doctors‐in‐training. Each participant had a unique code. The first part of the code denotes their grade and the last part denotes their sex. Thus, the code “F1A‐F" reflects a foundation year 1 (F1) participant who is female
| Topic | Exemplar quotes |
|---|---|
| 3.1. Acceptability of intervention |
3.1.1 |
| 3.2. Authenticity of intervention |
3.2.1 “ |
| 3.3. Experience of feedback |
3.3.1 “ |
| 3.4. Receiving feedback from pharmacists |
3.4.1 “ |
| 3.5. Characteristics of a feedback provider |
3.5.1 “ |
| 3.6. Participant reflections on filming |
3.6.1 “ |
| 3.7. Commitment to behaviour change |
3.7.1 “ |