Literature DB >> 31312084

Using Smartphones to Improve Treatment Retention Among Impoverished Substance-Using Appalachian Women: A Naturalistic Study.

Darcie C Johnston1, W David Mathews2, Adam Maus1, David H Gustafson1,3.   

Abstract

OBJECTIVES: Longer retention in treatment is associated with positive outcomes. For women, who suffer worse drug-related problems than men, social technologies, which are more readily adopted by women, may offer promise. This naturalistic study examined whether a smartphone-based relapse-prevention system, A-CHESS (Addiction-Comprehensive Health Enhancement Support System), could improve retention for women with substance use disorders in an impoverished rural setting.
METHODS: A total of 98 women, age 18 to 40, in southeastern Kentucky and mandated to treatment, received A-CHESS with intensive outpatient treatment for 6 months. For comparison, data were obtained for a similar but non-equivalent group of 100 same-age women also mandated to treatment in the same clinics during the period. Electronic medical record data on length-of-stay and treatment service use for both groups were analyzed, with A-CHESS use data, to determine whether those using A-CHESS showed better retention than those without.
RESULTS: Women with A-CHESS averaged 780 service units compared with 343 for the comparison group. For those with discharge dates prior to the study's end, A-CHESS patients stayed in treatment a mean of 410 vs 262 days for the comparison group.
CONCLUSIONS: Given associations between retention and positive outcomes, mobile health technology such as A-CHESS may help improve outcomes among women, especially in settings where access to in-person services is difficult. The findings, based on a non-equivalent comparison, suggest the need for further exploration with rigorous experimental designs to determine whether and to what degree access to a smartphone with A-CHESS may extend and support recovery for women.

Entities:  

Keywords:  Appalachian region; Women; aftercare; alcohol-related disorders; opioid-related disorders; retention in care; rural health services; social networking; substance-related disorders; telemedicine

Year:  2019        PMID: 31312084      PMCID: PMC6614935          DOI: 10.1177/1178221819861377

Source DB:  PubMed          Journal:  Subst Abuse        ISSN: 1178-2218


Introduction

Alcohol, opioid, and other substance use disorders (SUDs) are chronic conditions characterized by frequent relapse.[1-4] Evidence shows that continuing care for SUDs is associated with better outcomes,[5-7] and that retention in treatment is a key predictor of successful recovery.[8-10] Nonetheless, patients are not typically offered continuing care with ongoing monitoring,[1,11,12] in part because of the overstressed infrastructure for delivering SUD treatment.[13] Mobile health (mHealth) technology offers a way to provide continuing care by making recovery support, information, and monitoring available to patients virtually anytime and anywhere[4,14] without further stressing the infrastructure. This method of delivering care could be especially important in rural areas, where access can be difficult, even when patients are motivated to attend scheduled appointments, group sessions, and 12-step meetings. In addition, mHealth systems may be especially effective for women, who have been shown to adopt social technologies more readily than men, even though they are less confident of their technology skills in certain contexts.[15-20] At the same time, women with SUDs, in comparison to men, exhibit worse drug, health, emotional, and employment problems,[21] and young mothers with SUDs may fare especially poorly.[22] As such, gender-based solutions are worth seeking, and technology social features could help answer the call. This article describes a naturalistic, non-equivalent control group quasi-experiment conducted to assess the potential value of an mHealth system to women in a setting with significant access challenges. Specifically, our goal was to evaluate whether an evidence-based relapse-prevention smartphone system known as A-CHESS (Addiction-Comprehensive Health Enhancement Support System[3,23]) system could increase retention in treatment among women with SUDs in an isolated, impoverished rural setting. The naturalistic design enabled observation of the women as they would actually behave in these conditions, informing questions for more controlled study and suggesting directions for treatment. To our knowledge, this is one of the first studies to evaluate the impact of mHealth on retention in addiction treatment for women.[24]

Methods

Participants and procedures

A-CHESS group

Participants were women with SUDs served by Kentucky River Community Care (KRCC) in southeast Kentucky’s mountainous coalfields. All came from the agency’s eight-county Appalachian area and were enrolled in an intensive outpatient program named “Solutions,” specifically for women mandated to treatment, offered in four KRCC clinics. Patients were age 18 to 40 years, reported having children or being pregnant, and were referred from child welfare agencies, drug courts, or other criminal justice agencies. Mothers had lost custody of their children or were likely to without treatment. Most reported co-occurring disorders, mainly depression and anxiety. The Solutions program provided individual and group counseling services, behavioral health education (eg, fundamentals of relapse prevention), and assistance establishing a support network with peers, providers, and the community. Patients and families received family counseling, during which they addressed relationship conflicts and strains due to addiction and, for those separated from children, prepared to live together again. Family members received awareness training about addiction, including warning signs and recommended responses to various problems. The clinics also offered psychiatric, psychological, case management, therapeutic rehabilitation, developmental, housing, and recovery coaching services. The KRCC Institutional Review Board (IRB) approved a project in which patients would receive A-CHESS for a period of 6 months in addition to Solutions. IRB and informed consent procedures were required by KRCC. Patients signed consent for treatment and research procedures and accepted in writing the terms and participant-protection conditions (eg, absence of coercion, ability to withdraw at any time) of the Substance Abuse and Mental Health Services Administration (SAMHSA) program that funded the project. SAMHSA required participants to sit for intake and follow-up interviews known as the GPRA (Government Performance and Results Act of 1993); SAMHSA’s Center for Substance Abuse Treatment’s CSAT GPRA Client Outcome Measures for Discretionary Programs[25] was used. Consenting to the A-CHESS study was not a condition of SUD treatment. PJ, a clinic staff media specialist and assistant to the chief information officer, was in charge of recruiting, intake, and training of all women who joined the study; she also collected and uploaded GPRA data to the federal database. During the data collection period (February 2012 to August 2014), PJ recruited and completed the intake GPRA with 180 women. GPRA responses at intake are reported in Table 1 to help establish a picture of the participants.
Table 1.

Characteristics of A-CHESS patients (N = 180), as reported on the GPRA at intake to the study.

GPRA measureTotal N respondingnPercent (n/N)
Race
 White18017697.8
 Hispanic18021.1
 African American18000
 Asian18010.55
 Native American18010.55
Employment status
 Unemployed17416293.1
 Income from any source1792212.3
Education
 11th grade or less1806435.6
 7th to 9th 30 16.7
 10th to 11th 34 18.9
 High school diploma or equivalent1805731.7
 Some college (without 4-year degree)1805832.2
Housing
 Own/rent1809854.4
 Living in someone else’s home1807742.8
 Other housing18031.7
 Homeless18021.1
Parental and children’s status
 Participants with children18017798.3
 Participants’ children living elsewhere by protective order17612772.2
Crime and criminal justice status
 On parole or probation1793016.8
 Awaiting charges, trial, or sentencing1792011.2
Physical health in last 30 days
 Hospitalized for physical ailment18063.3
 Outpatient treatment for physical condition1805731.7
 Emergency room visit1801810.0
 Overall health excellent or very good1783016.9
Mental health in last 30 days
 Drug use caused emotional problems180147.8
 Daily anxiety/tension (not drug-related)1805430.0
 Cognitive problems on 2 or more days[a]1806435.6
 Hallucinations18021.1
 Problems controlling violent temper180116.1
 Attempted suicide18010.55
Support seeking outside of treatment
 Self-help meetings, non-religious (eg, 12-step)1797038.9
 Self-help meetings, faith-based179126.7
 Family members when feeling troubled17912770.6
 No family or friend support for recovery179126.7
Violence and trauma
 Experienced violence or trauma in lifetime18012770.1

Abbreviations: A-CHESS, Addiction-Comprehensive Health Enhancement Support System; GPRA, Government Performance and Results Act.

Ns vary from 180 because a patient could decline to answer a given question. Percentages may not add up to 100 because of rounding, multiple possible responses, or no applicable response.

Phrased as “problems concentrating, understanding, or remembering.”

Characteristics of A-CHESS patients (N = 180), as reported on the GPRA at intake to the study. Abbreviations: A-CHESS, Addiction-Comprehensive Health Enhancement Support System; GPRA, Government Performance and Results Act. Ns vary from 180 because a patient could decline to answer a given question. Percentages may not add up to 100 because of rounding, multiple possible responses, or no applicable response. Phrased as “problems concentrating, understanding, or remembering.” As evidence of sincerity, patients were to return after the GPRA intake for their phone and training. Of the 180, a total of 98 (54.4%) returned to receive a phone and remained in treatment during their intervention period. The other 82 could have left treatment, been incarcerated, or disappeared to avoid incarceration, or they simply decided not to participate. Many expressed privacy concerns about using a KRCC phone, which may have been a factor for those deciding not to enter the study. Because of poor credit and inability to afford phones and access, most of the women (the exact number is unknown) had never owned or even used a smartphone and needed to be trained in use of the device (eg, texting, taking pictures) as well as the A-CHESS app. Participants received basic phone and A-CHESS training from PJ during group and individual sessions and via videos produced by the app’s developers. PJ also gave phones with A-CHESS to all counselors, enabling counselors to monitor patients and patients to contact counselors at any time. Study phones were serviced through a regional wireless company that had the greatest number of towers in the area and partnered with a national network for roaming. However, Internet access was a challenge. The women generally did not have WiFi at home and would go to public places for free access. Moreover, phone service could be unreliable, necessitating finding other locations where service was better. “That was hard,” said PJ. “Most of the women needed public transportation.” As testimony to the perceived value of the app, 47% of the women trained to use A-CHESS were still using it at the end of the 6-month study, despite these challenges. Phones were in limited supply. After each participant’s 6-month intervention period, she would return the phone to KRCC so that it could be given to a new participant. KRCC tracked each participant’s clinical service use from admission date until she left treatment. Leaving treatment was defined as not having received any clinic service for 3 months. Information about the primary substance bringing each patient to treatment was not available to the research team. However, at intake to the study, patients reported their primary substance used in the last 30 days on the GPRA interview. Of specific drugs reported, opioids were the most frequently named (11.7%); alcohol was named by 3.3% (see Table 2). The number of women reporting no substance use (43.3%) was much higher than one might expect from a group in SUD treatment, but since the GPRA reflects substance use after treatment was already under way, patients may have been truthful in denying recent use. Also, as referrals from drug court and child welfare, patients were being drug tested regularly and likely feared losing child custody or being incarcerated.[4] Because the GPRA reports do not reflect substance use on entering treatment, they are not reliable for analysis, but they suggest a general picture of the types of substances used and for this reason are reported.
Table 2.

Primary substance used by A-CHESS patients (N = 180) in the past 30 days, as reported on the GPRA at intake to the study.

Primary substancen%
Unspecified illegal drugs4122.8
Opioids[a]2111.7
Marijuana/hashish1810.0
Benzodiazepines126.7
Alcohol63.3
Barbiturates31.7
Amphetamines10.6
No substance use7843.3
Total 180 100

Abbreviations: A-CHESS, Addiction-Comprehensive Health Enhancement Support System; GPRA, Government Performance and Results Act.

Percentages are rounded to the nearest one-tenth.

Opioids were Percocet (10, or 5.6%), OxyContin/oxycodone (5, or 2.8%), morphine (2, or 1.1%), codeine (1, or 0.6%), Dilaudid (1, or 0.6%), heroin (1, or 0.6%), and non-prescription methadone (1, or 0.6%).

Primary substance used by A-CHESS patients (N = 180) in the past 30 days, as reported on the GPRA at intake to the study. Abbreviations: A-CHESS, Addiction-Comprehensive Health Enhancement Support System; GPRA, Government Performance and Results Act. Percentages are rounded to the nearest one-tenth. Opioids were Percocet (10, or 5.6%), OxyContin/oxycodone (5, or 2.8%), morphine (2, or 1.1%), codeine (1, or 0.6%), Dilaudid (1, or 0.6%), heroin (1, or 0.6%), and non-prescription methadone (1, or 0.6%).

Comparison group

At the conclusion of the study, KRCC developed a data set of 231 patients meeting inclusion criteria. Each (1) was female, (2) had a SUD diagnosis, and (3) received treatment in KRCC outpatient programs (4) during the same period that the study took place. Patients were (5) of the same age as the A-CHESS group (range = 18-40; Ms = 27.89 and 27.93, respectively) and (6) from the same eight-county area. Like the intervention group, (7) all were mandated to treatment, suggesting a similar degree of SUD severity. From this data set, 100 were randomly selected, using SPSS, to form a post hoc comparison group.

Intervention

Participants received at no cost to them a large-screen Android smartphone with unlimited voice and texting capacity, 5 GB monthly data, and A-CHESS, which has been shown in a randomized clinical trial to improve adherence to treatment.[23] A-CHESS offered more than a dozen services supporting addiction recovery in these ways: (1) communication with addiction experts and peer support groups, including confidential chat rooms and private messaging; (2) timely monitoring, feedback-related assessment, and links to interventions addressing relapse risk; (3) reminders and alerts to encourage adherence to therapeutic goals; (4) one-touch communication with the patient’s counselor and/or case manager; (5) addiction-related educational materials and tools; and (6) customizable location-based resources (eg, alerts that would display if a patient neared a high-risk location such as a bar or supplier she used to frequent). Screen shots of A-CHESS are available at http://chess.wisc.edu/achess-archive/. Each week, A-CHESS checked in with a brief survey on the phone’s screen. This survey collected patient data on recent substance use as well as status on five protective and five risk factors from the Brief Alcohol Monitor.[26] A-CHESS used the check-in information for triage and feedback. Case managers and counselors received a summary of each patient’s check-in data any time they wished, the day before a scheduled appointment, and whenever a patient reported a lapse. System data revealed 94 unique A-CHESS users, indicating that 4 of the 98 participants who received smartphones never logged in to the app, although they likely used the phone for other purposes. These 4 women would have been among the first to enter the study. “All [98 participants] were trained on their own phone,” according to PJ. “But in the very beginning, we hadn’t fully set up the process, and we quickly realized we needed to show them how to use the app at the same time they got the phone. The first few didn’t have that and might have never logged in.”

Data collection and analysis

A-CHESS use

For each A-CHESS patient, de-identified data on logins and page views were collected by computer at the Center for Health Enhancement Systems Studies, University of Wisconsin–Madison, where the app was developed.

GPRA reports

Responses to A-CHESS patients’ intake and follow-up GPRA surveys were entered into the federal database by KRCC staff (PJ) and made available to author WDM. The comparison patients comprise a post hoc data set; they were not study participants and did not sit for the GPRA. GPRA interview responses are therefore used only for descriptive insight and not for analyses.

Outpatient treatment data from medical records

For each patient in both the A-CHESS and comparison groups, all treatment data came from the KRCC electronic medical record (EMR) database and were de-identified prior to delivery from the agency to the research team. Data consisted of dates of birth, admission, and discharge; diagnosis; types of clinical services received; and number of service units received. Service types were group sessions, individual sessions, peer support, case management sessions, and drug screens, reported as 15-min units. Clinical service types and units were gathered for both groups post hoc. EMR data enabled the calculation of length of stay in treatment, number of units received of each clinical service, and total number of units received. Levene’s test[27] was used to assess the equality of variances for retention-in-service variable distributions. This indicated inequality between the two groups and suggested non-parametric analysis. Thus, Mann-Whitney U and chi-square tests were used to analyze between-group effects.

Outcome measures

It was hypothesized that patients who used A-CHESS would show better retention in treatment than women without it, as indicated by the length of time between admission and discharge dates in the EMR. It was also hypothesized that these patients would access more care, as indicated both by the number of units of clinical service according to type and by the sum of all service units.

Results

EMR data and outcome measures

The Mann-Whitney U test revealed significant differences that favored the A-CHESS group (P < .001; Bonferroni adjusted alpha = .007) for length of stay; for case management, group sessions, individual sessions, and drug screens; and for total units of service. The difference between groups for peer support was nonsignificant (P = .067). All effect sizes are in the moderate range (.47-.64). EMR records revealed that A-CHESS patients stayed in treatment a mean of 410 days, vs 262 days for the comparison group (Table 3). These length-of-stay results include only the 68 A-CHESS and 84 comparison patients with discharge dates prior to the end of the study. Eventual discharge dates for the remaining 30 (30.6%) A-CHESS women and 16 (16.0%) comparison women are unknown; their length-of-stay, when calculated as of the final date of the study, shows a similar trend: 584 days vs 360 days. For all participants, when length of stay is calculated by either discharge or end-of-study date, as applicable, M = 463 days for the 98 A-CHESS patients and M = 277 days for the 100 comparison patients.
Table 3.

Length of stay in treatment and clinical services used for A-CHESS and comparison groups.

OutcomeGroupNMeanSD95% Confidence interval P Effect size (Cohen’s d)
Length of stay.0000.47
A-CHESS68[a]410.0240.82351.74-468.32
Comparison84[a]261.7212.74213.94-306.27
Case mgmnt. sessions.0000.57
A-CHESS74[b]8.365.307.14-9.59
Comparison47[b]4.683.673.60-5.76
Group sessions.0000.54
A-CHESS95[b]668.52461.24574.56-762.47
Comparison88[b]332.56412.16245.23-419.89
Individual sessions.0000.64
A-CHESS97[b]120.16105.0299.00-141.33
Comparison96[b]46.6944.2637.72-55.66
Drug screens.0000.50
A-CHESS93[b]30.9420.3126.75-35.12
Comparison80[b]17.0019.0312.76-21.24
Peer support.0670.51
A-CHESS21[b]31.4834.6015.73-47.23
Comparison11[b]13.4516.322.49-24.42
All services.0000.57
A-CHESS98[b]779.59547.18669.89-889.30
Comparison100[b]342.77435.05256.45-429.90

Abbreviation: A-CHESS, Addiction-Comprehensive Health Enhancement Support System.

Length of stay is measured by number of days in treatment from admission date to discharge date; all other outcomes (services) are measured as 15-min increments of use. A Bonferroni adjustment was made to account for multiple comparisons, alpha = .007.

Clients with treatment discharge dates only.

Number of records showing service use out of 98 possible for A-CHESS group and 100 possible for comparison group.

Length of stay in treatment and clinical services used for A-CHESS and comparison groups. Abbreviation: A-CHESS, Addiction-Comprehensive Health Enhancement Support System. Length of stay is measured by number of days in treatment from admission date to discharge date; all other outcomes (services) are measured as 15-min increments of use. A Bonferroni adjustment was made to account for multiple comparisons, alpha = .007. Clients with treatment discharge dates only. Number of records showing service use out of 98 possible for A-CHESS group and 100 possible for comparison group. For clinical services used, EMRs revealed that the 98 A-CHESS patients received an average of 779.6 total units of service (measured in 15-min increments) vs 342.8 total units for the 100 comparison patients. Table 3 shows average use of each service for the two groups, with A-CHESS patients logging roughly twice as many units for every service.

A-CHESS use

Table 4 shows the monthly use patterns of A-CHESS participants logging in throughout their intervention period. While app use decreased over time, almost half of the patients (46.8%) were still logging in during their final month of the study, a rate that is significantly better than the average for even the most frequently downloaded mHealth apps on the market, which typically show rapid drop-off in use.[28-30] In one study, 25% of users were found to abandon mHealth apps after just one use[31]; another found that the average retention rate is 20% after 90 days.[32]
Table 4.

A-CHESS use among intervention group participants using the app (n = 94).

A-CHESS use measureMonth 1Month 2Month 3Month 4Month 5Month 6
Logins to A-CHESS
 No. (%) of users94 (100)82 (87.2)77 (81.9)67 (71.3)60 (63.8)44 (46.8)
 Total logins647642693511275124151219
 Avg. logins per user68.8952.0645.6041.0640.2527.70
Weekly survey check-in
 No. (%) of users89 (94.7)63 (67.0)58 (61.7)53 (56.4)42 (44.7)28 (29.8)
 Total pages viewed3634184615121216842402
 Avg. pages per user40.8329.3026.0722.9420.0514.36
Discussion groups
 No. (%) of users80 (85.1)65 (69.1)55 (58.5)50 (53.2)39 (41.5)27 (28.7)
 Total pages viewed24 33012 3727448608544191340
 Avg. pages per user304.13190.34135.42121.70113.3149.63
Private messaging
 No. (%) of users93 (98.9)74 (78.7)64 (68.1)47 (50.0)45 (47.9)25 (26.6)
 Total pages viewed10 74755843970336523191319
 Avg. pages per user115.5575.4562.0371.6051.5352.76
Profiles (self and other members)
 No. (%) of users93 (98.9)50 (53.2)31 (33.0)30 (31.9)18 (19.2)9 (9.6)
 Total pages viewed11 7952626138417711356531
 Avg. pages per user126.8352.5244.6559.0375.3359.00
Events and announcements
 No. (%) of users78 (83.0)31 (33.0)23 (24.5)17 (18.1)9 (9.6)8 (8.5)
 Total pages viewed6298363652729
 Avg. pages per user8.062.682.743.823.003.63
Information tools
 No. (%) of users79 (84.0)33 (35.1)27 (28.7)20 (21.3)16 (17.0)6 (6.4)
 Total pages viewed8301286166337
 Avg. pages per user10.513.882.263.302.061.17
Audio interviews of people in recovery
 No. (%) of users69 (73.4)18 (19.1)13 (13.8)10 (10.6)4 (4.3)5 (5.3)
 Total pages viewed34840441347
 Avg. pages per user5.042.223.381.301.001.40
Personal motivations
 No. (%) of users28 (29.8)5 (5.3)7 (7.4)1 (1.1)1 (1.1)3 (3.2)
 Total pages viewed326185610611
 Avg. pages per user11.643.608.0010.006.003.67
Audio relaxation and meditations
 No. (%) of users58 (61.7)12 (12.8)5 (5.3)5 (5.3)7 (7.4)2 (2.1)
 Total pages viewed20717179163
 Avg. pages per user3.571.423.401.802.291.50
Recovery podcasts
 No. (%) of users45 (47.9)14 (14.9)7 (7.4)7 (7.4)6 (6.4)2 (2.1)
 Total pages viewed219241821222
 Avg. pages per user4.871.712.573.003.671.00

Abbreviation: A-CHESS, Addiction-Comprehensive Health Enhancement Support System.

A-CHESS use among intervention group participants using the app (n = 94). Abbreviation: A-CHESS, Addiction-Comprehensive Health Enhancement Support System. In month 3, average A-CHESS logins per user numbered 45.6, or an average of 1.5 times per day; in month 6, average logins numbered 27.7, or an average of about 1 time per day. The most visited features were the Weekly Survey check-in, which provided feedback to both the patient and the clinic counselor; Discussion Groups, which function like chat rooms for the closed community of the participants; and Private Messages, which function like email between participants. Between 27% and 30% of all A-CHESS participants were using each of these three features at 6 months. The remaining features were viewed by fewer than 10% of participants at 6 months. These included announcements of events and meetings, informational resources such as news and links to relevant websites, inspirational recordings of people in recovery telling their stories, participants’ own photos and phrases for motivation, audio relaxation and meditation modules, and podcasts of recovery meeting keynote addresses. Profiles were visited less over time, but this might be expected as relationships developed.

GPRA intake and follow-up interviews

For reasons described above, GPRA reports of substance use do not indicate change between study intake and follow-up. Generally for the GPRA, in the absence of control or comparison group responses, no pre-post differences can be attributed to A-CHESS, but one change may be worth noting: While unemployment was extremely high (93.1% at intake, 88% at follow-up), it appears that efforts to improve were being made, based on reported rates of enrollment in educational or vocational programming, which increased from 6.7% to 13.3% at follow-up.

Discussion

A-CHESS patients with known discharge dates stayed in treatment 156.7% as long as the patients without it (410 days vs 262 days). In addition, all patients with A-CHESS received more than twice (227.4%) as many service units (780 units vs 343 units). Given the associations between retention in treatment and positive outcomes, these results suggest that a smartphone containing A-CHESS, used with intensive outpatient treatment, has potential to improve long recovery rates for women with an SUD in an impoverished and/or isolated area. There are several possible reasons why A-CHESS might have improved retention. First, A-CHESS data revealed strong and sustained use of the app’s social and communication features, which enabled patients to communicate with their counselors and other group members whenever and as often as needed. The Weekly Survey prompted contact between patient and counselor by regularly informing the counselor of the patient’s status on both negative and positive variables, laying groundwork for treatment sessions, and opening the door for communication via private messages or phone calls. Patients also made considerable use of Discussion Groups and Private Messages, the two main peer support features. The ability to communicate with one another anywhere, anytime may have created a camaraderie that increased the willingness to attend group sessions and other treatment services.[33] As one KRCC counselor (SS) put it, “A-CHESS made a major difference for every woman. They always had access to someone to help.” With these features, A-CHESS may have served as an intensifier of treatment. Other possible reasons, which should be monitored in future studies, reflect the key principles of self-determination theory,[23,34] which holds that a person’s adaptive functioning improves when three needs are met: (1) feeling competent, (2) feeling connected to others, and (3) feeling internally motivated rather than coerced. A-CHESS could have helped patients feel competent merely by being a tool in their hands that they had the choice to use. More specifically, certain features may have helped them cope with daily stressors, increasing perceptions of competence. For example, feedback from the Weekly Survey—which was used more than any other feature—pointed out when cravings seemed to be highest and then prompted patients to features designed to help them cope with those cravings. The coping features, such as informational resources, meeting announcements, and relaxation recordings, were not popular over time, though, possibly because there was not enough content to sustain interest. In terms of feeling connected to others, A-CHESS was most used for its social features, as described above, which is consistent with previous findings that women, more than men, use social media, even when they are not confident with technology.[15-20] The frequent use of these features, as indicated by the use data, may well have fostered a sense of support and connection among the participants. Furthermore, a feeling of belonging in a closed group of women who were all recovery-oriented may have helped the women maintain their commitment to succeed. Finally, intrinsic motivation to stay with treatment might have been boosted with a combination of A-CHESS features. A new inspirational message appeared each day on the home screen when a user logged in. Women could also upload personally meaningful photos and words to remind themselves of their reasons to stay clean, and they could listen to interviews with people in recovery as well as podcasts of speeches from 12-step conferences and other recovery events. However, other than the new inspirational message that every user saw each day she opened the app, use of these features was low after the first month. As with informational resources, motivational content was limited in terms of quantity or refreshment, which might explain the lack of continuing interest. Subsequent to this study, A-CHESS developments have included new motivational and informational tools, in terms of both type and number, as well as navigational and display enhancements for ease of use and visual appeal. In future studies, outcomes based on self-determination theory should be monitored.

Limitations

A number of limitations prevent generalizing from the results, but the results raise interesting questions and contribute to the literature on those questions. First, our quasi-experimental posttest-only design employed a similar but non-equivalent comparison group that was not created through random assignment. The project’s goal was to evaluate A-CHESS in a natural setting, where the study would not interfere with typical treatment, a condition that made random assignment and a pretest virtually impossible. There are benefits to this kind of naturalistic study. Data collections do not interfere with treatment as usual; this is a natural sample involving patients in an intensive treatment program instead of a highly restricted sampling. Unlike many randomized trials where outcomes are measured by qualitative surveys (which in mandated treatment conditions are positively related to recovery-oriented responses),[4] data used in this study are based solely on actual behaviors and not self-report. The study also provides information about how many services would be delivered and how long the patient would stay in treatment in the absence of A-CHESS, an important consideration given that treatment retention is among the most important predictors of sustained recovery.[35] There are costs as well. Namely, the value of information provided by a comparison group depends on how similar the group is to the treatment group.[36] As with any situation where a comparison group is used in a quasi-experimental design, our non-equivalent control group had selection biases[37]; even random selection of a subset from the pool who met criteria may have introduced bias. The absence of a true control group created through random selection of study participants makes it difficult to determine whether treatment outcomes are due to treatment or to differences between groups. We controlled for many sources of dissimilarity, and given the homogeneity of the counties in terms of minorities and economic conditions, the groups were also likely to be similar demographically. Still, we could not control for commitment to recovery or actual substance use during the study. Furthermore, even though patients were mandated to treatment, implying at least a moderate addiction severity for all, the severities may have been different. As a result, we cannot say the results are definitive, only provocative. Second, any effects of A-CHESS cannot be separated from access to a smartphone, which was a first for most women and which on its own may have improved the social support and information the women received, providing them with means and motivation to change. However, a study conducted several years ago suggests that A-CHESS rather than the phone was responsible.[38] In that randomized clinical trial, breast cancer patients were assigned to (1) a control group that received books and audio resources about cancer, (2) a group that received a laptop plus Internet access but not CHESS (the predecessor to A-CHESS), or (3) a group that received a laptop with CHESS for breast cancer. In that 9-month study (the final 3 months were follow-up after removing the computers), the Internet group was never superior to the no-laptop control group, while the CHESS group was superior to both other groups in quality of life and social support outcomes. In that case, it was demonstrably CHESS that made a difference. Given that most women did not have their own computers when that study took place, the computer-based interventions may have offered similar novelty as the smartphones for the A-CHESS women in Kentucky. In addition, a separate short survey for the A-CHESS patients after participating in the current study suggests that A-CHESS itself helped treatment, with 84.2% responding it helped “quite a lot” (52.6%) or “somewhat” (31.6%); no participant responded that it helped “not at all.” But only two of the four clinics returned the survey, so while responses were positive, they are not reliable. Third, this study examined retention in treatment, not recovery outcomes. We do not know that patients with A-CHESS had improved recovery outcomes, such as fewer days of substance use or greater number of days of continuous abstinence. However, given that retention is key to successful outcomes, we can speculate that they were more likely to have better recovery outcomes than the comparison group, whose retention indicators were markedly lower. A final limitation is that because A-CHESS was used by counselors and case managers along with the intensive outpatient treatment to maintain connections with study participants, we do not know whether A-CHESS alone would constitute effective continuing care.

Conclusions

The results of this quasi-experiment merit further exploration with more rigorous experimental designs.[39] Questions to pursue include: Do patients in SUD treatment have better retention when provided with A-CHESS than do patients without the technology? (Some data on this have begun to appear.)[24] Do women have better retention and improved outcomes in comparison with men when provided with A-CHESS? Would a smartphone alone vs a smartphone with A-CHESS function as effective continuing care? Does the cost-effectiveness of A-CHESS justify the expense of providing a smartphone for continuing care for SUDs? The results of the project, combined with earlier evidence,[38] suggest that the technology might improve both access to and retention in continuing care, especially for women in isolated or impoverished rural areas.
  18 in total

1.  Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being.

Authors:  R M Ryan; E L Deci
Journal:  Am Psychol       Date:  2000-01

Review 2.  Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation.

Authors:  A T McLellan; D C Lewis; C P O'Brien; H D Kleber
Journal:  JAMA       Date:  2000-10-04       Impact factor: 56.272

3.  Can the national addiction treatment infrastructure support the public's demand for quality care?

Authors:  A Thomas McLellan; Deni Carise; Herbert D Kleber
Journal:  J Subst Abuse Treat       Date:  2003-09

Review 4.  Substance abuse treatment entry, retention, and outcome in women: a review of the literature.

Authors:  Shelly F Greenfield; Audrey J Brooks; Susan M Gordon; Carla A Green; Frankie Kropp; R Kathryn McHugh; Melissa Lincoln; Denise Hien; Gloria M Miele
Journal:  Drug Alcohol Depend       Date:  2006-06-08       Impact factor: 4.492

Review 5.  Reconsidering the evaluation of addiction treatment: from retrospective follow-up to concurrent recovery monitoring.

Authors:  A Thomas McLellan; James R McKay; Robert Forman; John Cacciola; Jack Kemp
Journal:  Addiction       Date:  2005-04       Impact factor: 6.526

6.  Internet-Based Interactive Support for Cancer Patients: Are Integrated Systems Better?

Authors:  David H Gustafson; Robert Hawkins; Fiona McTavish; Suzanne Pingree; Wei Chih Chen; Kanittha Volrathongchai; William Stengle; James A Stewart; Ronald C Serlin
Journal:  J Commun       Date:  2008-06

7.  Explicating an evidence-based, theoretically informed, mobile technology-based system to improve outcomes for people in recovery for alcohol dependence.

Authors:  David H Gustafson; Bret R Shaw; Andrew Isham; Timothy Baker; Michael G Boyle; Michael Levy
Journal:  Subst Use Misuse       Date:  2011       Impact factor: 2.164

8.  Gender Differences Among In- and Out-of-Treatment Opioid-Addicted Individuals.

Authors:  Sharon M Kelly; Robert P Schwartz; Kevin E O'Grady; Shannon Gwin Mitchell; Heather Schacht Reisinger; James A Peterson; Michael H Agar; Barry S Brown
Journal:  Am J Drug Alcohol Abuse       Date:  2009       Impact factor: 3.829

Review 9.  Continuing care research: what we have learned and where we are going.

Authors:  James R McKay
Journal:  J Subst Abuse Treat       Date:  2009-03

10.  Social science. Computational social science.

Authors:  David Lazer; Alex Pentland; Lada Adamic; Sinan Aral; Albert-Laszlo Barabasi; Devon Brewer; Nicholas Christakis; Noshir Contractor; James Fowler; Myron Gutmann; Tony Jebara; Gary King; Michael Macy; Deb Roy; Marshall Van Alstyne
Journal:  Science       Date:  2009-02-06       Impact factor: 47.728

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  7 in total

Review 1.  Challenges in Participant Engagement and Retention Using Mobile Health Apps: Literature Review.

Authors:  Saki Amagai; Sarah Pila; Aaron J Kaat; Cindy J Nowinski; Richard C Gershon
Journal:  J Med Internet Res       Date:  2022-04-26       Impact factor: 7.076

2.  Using community-based participatory methods to design a digital intervention for mothers with substance use disorders: Qualitative results from focus group discussions.

Authors:  Phyllis Raynor; Cynthia Corbett; Ron Prinz; Delia West; Alain Litwin
Journal:  Perspect Psychiatr Care       Date:  2021-05-03       Impact factor: 2.186

3.  "It's way more than just writing a prescription": A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use disorder.

Authors:  Elizabeth C Saunders; Sarah K Moore; Olivia Walsh; Stephen A Metcalf; Alan J Budney; Patricia Cavazos-Rehg; Emily Scherer; Lisa A Marsch
Journal:  Addict Sci Clin Pract       Date:  2021-01-27

4.  Six-month outcomes of the HOPE smartphone application designed to support treatment with medications for opioid use disorder and piloted during an early statewide COVID-19 lockdown.

Authors:  Jacqueline Hodges; Marika Waselewski; William Harrington; Taylor Franklin; Kelly Schorling; Jacqueline Huynh; Alexa Tabackman; Kori Otero; Karen Ingersoll; Nassima Ait-Daoud Tiouririne; Tabor Flickinger; Rebecca Dillingham
Journal:  Addict Sci Clin Pract       Date:  2022-03-07

5.  Testing an mHealth System for Individuals With Mild to Moderate Alcohol Use Disorders: Protocol for a Type 1 Hybrid Effectiveness-Implementation Trial.

Authors:  Linda S Park; Ming-Yuan Chih; Christine Stephenson; Nicholas Schumacher; Randall Brown; David Gustafson; Bruce Barrett; Andrew Quanbeck
Journal:  JMIR Res Protoc       Date:  2022-02-18

6.  Implementation of Smartphone Systems to Improve Quality of Life for People With Substance Use Disorder: Interim Report on a Randomized Controlled Trial.

Authors:  David Gustafson; Julie Horst; Deanne Boss; Kathryn Fleddermann; Nora Jacobson; Mathew Roosa; J Charles Ross; Rachel Gicquelais; Olivia Vjorn; Tracy Siegler; Todd Molfenter
Journal:  JMIR Hum Factors       Date:  2022-07-14

Review 7.  Practical Technology for Expanding and Improving Substance Use Disorder Treatment: Telehealth, Remote Monitoring, and Digital Health Interventions.

Authors:  Mary M Sweeney; August F Holtyn; Maxine L Stitzer; David R Gastfriend
Journal:  Psychiatr Clin North Am       Date:  2022-07-31
  7 in total

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