| Literature DB >> 3130346 |
H Ochi1, S Watanabe, H Yamamoto.
Abstract
A possible new heritable fragile site at band 8q24.1, which is known to be a breakpoint in various cancers and contains the c-myc locus, was found in the lymphocytes from a woman with mastopathy. This fragile site was induced by distamycin A treatment, and expressed as gaps and breaks in 18% of the metaphases examined. The lymphocytes from one of her two sons examined also revealed gaps or breaks at the same site of chromosome 8 in 34% of the metaphases. This fragile 8q24.1 band is considered to be a new heritable fragile site induced by distamycin A.Entities:
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Year: 1988 PMID： 3130346 PMCID： PMC5917470 DOI： 10.1111/j.1349-7006.1988.tb01568.x
Source DB: PubMed Journal: Jpn J Cancer Res ISSN： 0910-5050