Literature DB >> 31285579

Reconciling S-LDSC and LDAK functional enrichment estimates.

Steven Gazal1,2, Carla Marquez-Luna3,4, Hilary K Finucane5, Alkes L Price6,7,8.   

Abstract

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Year:  2019        PMID： 31285579      PMCID： PMC7006477          DOI： 10.1038/s41588-019-0464-1

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


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  10 in total

1.  Improved heritability estimation from genome-wide SNPs.

Authors:  Doug Speed; Gibran Hemani; Michael R Johnson; David J Balding
Journal:  Am J Hum Genet       Date:  2012-12-07       Impact factor: 11.025

2.  Common SNPs explain a large proportion of the heritability for human height.

Authors:  Jian Yang; Beben Benyamin; Brian P McEvoy; Scott Gordon; Anjali K Henders; Dale R Nyholt; Pamela A Madden; Andrew C Heath; Nicholas G Martin; Grant W Montgomery; Michael E Goddard; Peter M Visscher
Journal:  Nat Genet       Date:  2010-06-20       Impact factor: 38.330

3.  Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

Authors:  Steven Gazal; Hilary K Finucane; Nicholas A Furlotte; Po-Ru Loh; Pier Francesco Palamara; Xuanyao Liu; Armin Schoech; Brendan Bulik-Sullivan; Benjamin M Neale; Alexander Gusev; Alkes L Price
Journal:  Nat Genet       Date:  2017-09-11       Impact factor: 38.330

4.  Genetic and epigenetic fine mapping of causal autoimmune disease variants.

Authors:  Kyle Kai-How Farh; Alexander Marson; Jiang Zhu; Markus Kleinewietfeld; William J Housley; Samantha Beik; Noam Shoresh; Holly Whitton; Russell J H Ryan; Alexander A Shishkin; Meital Hatan; Marlene J Carrasco-Alfonso; Dita Mayer; C John Luckey; Nikolaos A Patsopoulos; Philip L De Jager; Vijay K Kuchroo; Charles B Epstein; Mark J Daly; David A Hafler; Bradley E Bernstein
Journal:  Nature       Date:  2014-10-29       Impact factor: 49.962

5.  Fine-mapping inflammatory bowel disease loci to single-variant resolution.

Authors:  Hailiang Huang; Ming Fang; Luke Jostins; Maša Umićević Mirkov; Gabrielle Boucher; Carl A Anderson; Vibeke Andersen; Isabelle Cleynen; Adrian Cortes; François Crins; Mauro D'Amato; Valérie Deffontaine; Julia Dmitrieva; Elisa Docampo; Mahmoud Elansary; Kyle Kai-How Farh; Andre Franke; Ann-Stephan Gori; Philippe Goyette; Jonas Halfvarson; Talin Haritunians; Jo Knight; Ian C Lawrance; Charlie W Lees; Edouard Louis; Rob Mariman; Theo Meuwissen; Myriam Mni; Yukihide Momozawa; Miles Parkes; Sarah L Spain; Emilie Théâtre; Gosia Trynka; Jack Satsangi; Suzanne van Sommeren; Severine Vermeire; Ramnik J Xavier; Rinse K Weersma; Richard H Duerr; Christopher G Mathew; John D Rioux; Dermot P B McGovern; Judy H Cho; Michel Georges; Mark J Daly; Jeffrey C Barrett
Journal:  Nature       Date:  2017-06-28       Impact factor: 49.962

6.  Reevaluation of SNP heritability in complex human traits.

Authors:  Doug Speed; Na Cai; Michael R Johnson; Sergey Nejentsev; David J Balding
Journal:  Nat Genet       Date:  2017-05-22       Impact factor: 38.330

7.  SumHer better estimates the SNP heritability of complex traits from summary statistics.

Authors:  Doug Speed; David J Balding
Journal:  Nat Genet       Date:  2018-12-03       Impact factor: 38.330

8.  Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.

Authors:  Jian Yang; Andrew Bakshi; Zhihong Zhu; Gibran Hemani; Anna A E Vinkhuyzen; Sang Hong Lee; Matthew R Robinson; John R B Perry; Ilja M Nolte; Jana V van Vliet-Ostaptchouk; Harold Snieder; Tonu Esko; Lili Milani; Reedik Mägi; Andres Metspalu; Anders Hamsten; Patrik K E Magnusson; Nancy L Pedersen; Erik Ingelsson; Nicole Soranzo; Matthew C Keller; Naomi R Wray; Michael E Goddard; Peter M Visscher
Journal:  Nat Genet       Date:  2015-08-31       Impact factor: 38.330

9.  Partitioning heritability by functional annotation using genome-wide association summary statistics.

Authors:  Hilary K Finucane; Brendan Bulik-Sullivan; Alexander Gusev; Gosia Trynka; Yakir Reshef; Po-Ru Loh; Verneri Anttila; Han Xu; Chongzhi Zang; Kyle Farh; Stephan Ripke; Felix R Day; Shaun Purcell; Eli Stahl; Sara Lindstrom; John R B Perry; Yukinori Okada; Soumya Raychaudhuri; Mark J Daly; Nick Patterson; Benjamin M Neale; Alkes L Price
Journal:  Nat Genet       Date:  2015-09-28       Impact factor: 38.330

10.  Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations.

Authors:  Steven Gazal; Po-Ru Loh; Hilary K Finucane; Andrea Ganna; Armin Schoech; Shamil Sunyaev; Alkes L Price
Journal:  Nat Genet       Date:  2018-10-08       Impact factor: 38.330
  10 in total
  22 in total

1.  The distribution of common-variant effect sizes.

Authors:  Luke J O'Connor
Journal:  Nat Genet       Date:  2021-07-29       Impact factor: 38.330

2.  Evaluating and improving heritability models using summary statistics.

Authors:  Doug Speed; John Holmes; David J Balding
Journal:  Nat Genet       Date:  2020-03-23       Impact factor: 38.330

3.  Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics.

Authors:  Karthik A Jagadeesh; Kushal K Dey; Daniel T Montoro; Rahul Mohan; Steven Gazal; Jesse M Engreitz; Ramnik J Xavier; Alkes L Price; Aviv Regev
Journal:  Nat Genet       Date:  2022-09-29       Impact factor: 41.307

Review 4.  Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis.

Authors:  Tiffany Amariuta; Yang Luo; Rachel Knevel; Yukinori Okada; Soumya Raychaudhuri
Journal:  Immunol Rev       Date:  2019-11-28       Impact factor: 12.988

5.  Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Authors:  Soumya Raychaudhuri; Johji Inazawa; Toshimasa Yamauchi; Takashi Kadowaki; Michiaki Kubo; Yoichiro Kamatani; Kazuyoshi Ishigaki; Masato Akiyama; Masahiro Kanai; Atsushi Takahashi; Eiryo Kawakami; Hiroki Sugishita; Saori Sakaue; Nana Matoba; Siew-Kee Low; Yukinori Okada; Chikashi Terao; Tiffany Amariuta; Steven Gazal; Yuta Kochi; Momoko Horikoshi; Ken Suzuki; Kaoru Ito; Satoshi Koyama; Kouichi Ozaki; Shumpei Niida; Yasushi Sakata; Yasuhiko Sakata; Takashi Kohno; Kouya Shiraishi; Yukihide Momozawa; Makoto Hirata; Koichi Matsuda; Masashi Ikeda; Nakao Iwata; Shiro Ikegawa; Ikuyo Kou; Toshihiro Tanaka; Hidewaki Nakagawa; Akari Suzuki; Tomomitsu Hirota; Mayumi Tamari; Kazuaki Chayama; Daiki Miki; Masaki Mori; Satoshi Nagayama; Yataro Daigo; Yoshio Miki; Toyomasa Katagiri; Osamu Ogawa; Wataru Obara; Hidemi Ito; Teruhiko Yoshida; Issei Imoto; Takashi Takahashi; Chizu Tanikawa; Takao Suzuki; Nobuaki Sinozaki; Shiro Minami; Hiroki Yamaguchi; Satoshi Asai; Yasuo Takahashi; Ken Yamaji; Kazuhisa Takahashi; Tomoaki Fujioka; Ryo Takata; Hideki Yanai; Akihide Masumoto; Yukihiro Koretsune; Hiromu Kutsumi; Masahiko Higashiyama; Shigeo Murayama; Naoko Minegishi; Kichiya Suzuki; Kozo Tanno; Atsushi Shimizu; Taiki Yamaji; Motoki Iwasaki; Norie Sawada; Hirokazu Uemura; Keitaro Tanaka; Mariko Naito; Makoto Sasaki; Kenji Wakai; Shoichiro Tsugane; Masayuki Yamamoto; Kazuhiko Yamamoto; Yoshinori Murakami; Yusuke Nakamura
Journal:  Nat Genet       Date:  2020-06-08       Impact factor: 38.330

6.  Genetic analyses identify widespread sex-differential participation bias.

Authors:  Nicola Pirastu; Mattia Cordioli; Michel G Nivard; John R B Perry; Andrea Ganna; Priyanka Nandakumar; Gianmarco Mignogna; Abdel Abdellaoui; Benjamin Hollis; Masahiro Kanai; Veera M Rajagopal; Pietro Della Briotta Parolo; Nikolas Baya; Caitlin E Carey; Juha Karjalainen; Thomas D Als; Matthijs D Van der Zee; Felix R Day; Ken K Ong; Takayuki Morisaki; Eco de Geus; Rino Bellocco; Yukinori Okada; Anders D Børglum; Peter Joshi; Adam Auton; David Hinds; Benjamin M Neale; Raymond K Walters
Journal:  Nat Genet       Date:  2021-04-22       Impact factor: 38.330

7.  Characterizing the effect of background selection on the polygenicity of brain-related traits.

Authors:  Frank R Wendt; Gita A Pathak; Cassie Overstreet; Daniel S Tylee; Joel Gelernter; Elizabeth G Atkinson; Renato Polimanti
Journal:  Genomics       Date:  2020-12-02       Impact factor: 5.736

8.  Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.

Authors:  Yang Luo; Xinyi Li; Xin Wang; Steven Gazal; Josep Maria Mercader; Benjamin M Neale; Jose C Florez; Adam Auton; Alkes L Price; Hilary K Finucane; Soumya Raychaudhuri
Journal:  Hum Mol Genet       Date:  2021-07-28       Impact factor: 5.121

9.  Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.

Authors:  Wouter J Peyrot; Alkes L Price
Journal:  Nat Genet       Date:  2021-03-08       Impact factor: 38.330

10.  GxEsum: a novel approach to estimate the phenotypic variance explained by genome-wide GxE interaction based on GWAS summary statistics for biobank-scale data.

Authors:  Jisu Shin; Sang Hong Lee
Journal:  Genome Biol       Date:  2021-06-21       Impact factor: 13.583
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