Literature DB >> 3127991

Ovine platelet function and its inhibition by T-2 toxin.

P A Gentry1, A S Socha, M L Ross.   

Abstract

Ovine platelets suspended in homologous plasma aggregated effectively in response to adenosine-diphosphate, acid-soluble collagen and aggregated moderately to serotonin and arachidonic acid. Ovine platelet aggregation, in response to each agent, was inhibited in a concentration dependent fashion by T-2 toxin. The platelet aggregates which formed in the presence of T-2 toxin appeared to be less stable than aggregates in comparable control platelet suspensions.

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Year:  1987        PMID： 3127991     DOI： 10.1007/bf00380628

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  26 in total

Review 1.  The toxicology of mycotoxins.

Authors:  Y Ueno
Journal:  Crit Rev Toxicol       Date:  1985       Impact factor: 5.635

2.  The function of monkey (M. mulatta) platelets compared to platelets of pig, sheep, and man.

Authors:  V P Addonizio; L H Edmunds; R W Colman
Journal:  J Lab Clin Med       Date:  1978-06

3.  The structures of toxins from two strains of Fusarium tricinctum.

Authors:  J R Bamburg; N V Riggs; F M Strong
Journal:  Tetrahedron       Date:  1968-04       Impact factor: 2.457

4.  Characterisation of hemolysis induced by T-2 toxin.

Authors:  M I Gyongyossy-Issa; V Khanna; G G Khachatourians
Journal:  Biochim Biophys Acta       Date:  1985-02-15

5.  T-2 toxicosis and blood coagulation in young chickens.

Authors:  J A Doerr; P B Hamilton; H R Burmeister
Journal:  Toxicol Appl Pharmacol       Date:  1981-09-15       Impact factor: 4.219

6.  Plasma clot-promoting effect of collagen in relation to collagen-platelet interaction.

Authors:  P A Gentry; M D Schneider; J K Miller
Journal:  Am J Vet Res       Date:  1981-05       Impact factor: 1.156

7.  An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man.

Authors:  K M Meyers; J B Katz; R M Clemmons; J B Smith; H Holmsen
Journal:  Thromb Res       Date:  1980-10-01       Impact factor: 3.944

8.  Mechanism of inhibition of eukaryotic protein synthesis by trichothecene fungal toxins.

Authors:  E Cundliffe; M Cannon; J Davies
Journal:  Proc Natl Acad Sci U S A       Date:  1974-01       Impact factor: 11.205

9.  Inhibition of bovine platelet function by T-2 toxin, HT-2 toxin, diacetoxyscirpenol and deoxynivalenol.

Authors:  P K Chan; P A Gentry
Journal:  Food Chem Toxicol       Date:  1984-08       Impact factor: 6.023

10.  Alteration of the response of platelets to surface stimuli by pyrazole compounds.

Authors:  M A Packham; E S Warrior; M F Glynn; A S Senyi; J F Mustard
Journal:  J Exp Med       Date:  1967-07-01       Impact factor: 14.307
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  3 in total

1.  Comparison of the inhibition of deoxynivalenol and T-2 toxin on bovine and porcine platelet function.

Authors:  P A Gentry; G S Bondy; M L Ross
Journal:  Mycotoxin Res       Date:  1988-03       Impact factor: 3.833

2.  Comparative effects of trichothecene mycotoxins on bovine platelet function: Acetyl T-2 toxin, a more potent inhibitor than T-2 toxin.

Authors:  K Grandoni; P Gentry; B Holub; B Yagen
Journal:  Mycotoxin Res       Date:  1990-09       Impact factor: 3.833

3.  New aspects on efficient anticoagulation and antiplatelet strategies in sheep.

Authors:  Annika Weigand; Anja M Boos; Jürgen Ringwald; Maren Mieth; Ulrich Kneser; Andreas Arkudas; Oliver Bleiziffer; Dorothee Klumpp; Raymund E Horch; Justus P Beier
Journal:  BMC Vet Res       Date:  2013-10-03       Impact factor: 2.741
  3 in total

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