Michael C Grant1, Tetsuro Isada2, Pavel Ruzankin3, Glenn Whitman4, Jennifer S Lawton4, Jeffrey Dodd-O2, Viachaslau Barodka2. 1. Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Md; Armstrong Institute for Patient Safety and Quality, The Johns Hopkins Medical Institutions, Baltimore, Md. Electronic address: mgrant17@jhmi.edu. 2. Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Md. 3. Sobolev Institute of Mathematics, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia. 4. Department of Surgery, Division of Cardiac Surgery, The Johns Hopkins Medical Institutions, Baltimore, Md.
Abstract
OBJECTIVE: Enhanced recovery programs are multidisciplinary perioperative bundles of evidence-based process measures. Following the design and implementation of preanesthesia and intraoperative enhanced recovery programs for cardiac surgery guidelines, we evaluated the association between compliance and key clinical outcomes. METHODS: Consecutive patients undergoing cardiac surgery at a single tertiary medical center from September 2017 to June 2018 were included. Patients were stratified into low (0-4 measures) and high (5-7 measures) compliance groups and then 1-to-3 propensity matched on the basis of 15 patient and surgical covariables. The primary outcome of interest was time to postoperative extubation. Secondary outcomes included interval time point extubation rates and intensive care unit, floor, and hospital lengths of stay. RESULTS: A total of 451 patients were included in the study. After propensity matching (n = 315), patients in the high compliance group (n = 84) had a significant reduction in time to extubation (P < .001), floor length of stay (P = .01), and hospital length of stay (P = .03) compared with patients in the low compliance group (n = 231). Patients in the high compliance group were more likely to be extubated in the operating room (odds ratio, 35.8; 95% confidence interval, 10.66-168.75; P < .001) and within 6 hours of surgery (odds ratio, 2.6; 95% confidence interval, 1.18-6.07; P < .02). High compliance was associated with a median estimated time reduction of 3.4 hours to postoperative extubation (P < .001) and 19.4 hours in hospital length of stay (P = .01) compared with low compliance counterparts. There were no reintubations reported among patients extubated in the operating room (0/62 patients). CONCLUSIONS: There is value in developing phase-specific enhanced recovery programs guidelines, which improve rates of early extubation and affect the duration of stay after cardiac surgery. These results are hypothesis generating, and further prospective study is necessary to identify clinical impact of further program expansion.
OBJECTIVE: Enhanced recovery programs are multidisciplinary perioperative bundles of evidence-based process measures. Following the design and implementation of preanesthesia and intraoperative enhanced recovery programs for cardiac surgery guidelines, we evaluated the association between compliance and key clinical outcomes. METHODS: Consecutive patients undergoing cardiac surgery at a single tertiary medical center from September 2017 to June 2018 were included. Patients were stratified into low (0-4 measures) and high (5-7 measures) compliance groups and then 1-to-3 propensity matched on the basis of 15 patient and surgical covariables. The primary outcome of interest was time to postoperative extubation. Secondary outcomes included interval time point extubation rates and intensive care unit, floor, and hospital lengths of stay. RESULTS: A total of 451 patients were included in the study. After propensity matching (n = 315), patients in the high compliance group (n = 84) had a significant reduction in time to extubation (P < .001), floor length of stay (P = .01), and hospital length of stay (P = .03) compared with patients in the low compliance group (n = 231). Patients in the high compliance group were more likely to be extubated in the operating room (odds ratio, 35.8; 95% confidence interval, 10.66-168.75; P < .001) and within 6 hours of surgery (odds ratio, 2.6; 95% confidence interval, 1.18-6.07; P < .02). High compliance was associated with a median estimated time reduction of 3.4 hours to postoperative extubation (P < .001) and 19.4 hours in hospital length of stay (P = .01) compared with low compliance counterparts. There were no reintubations reported among patients extubated in the operating room (0/62 patients). CONCLUSIONS: There is value in developing phase-specific enhanced recovery programs guidelines, which improve rates of early extubation and affect the duration of stay after cardiac surgery. These results are hypothesis generating, and further prospective study is necessary to identify clinical impact of further program expansion.
Authors: Alexander A Brescia; Melissa J Clark; Patricia F Theurer; Shelly C Lall; Hassan W Nemeh; Richard S Downey; David E Martin; Reza R Dabir; Zewditu E Asfaw; Phillip L Robinson; Steven D Harrington; Divyakant B Gandhi; Jennifer F Waljee; Michael J Englesbe; Chad M Brummett; Richard L Prager; Donald S Likosky; Karen M Kim; Kiran H Lagisetty Journal: Ann Thorac Surg Date: 2020-12-04 Impact factor: 5.102
Authors: Alexander J Gregory; Michael C Grant; Edward Boyle; Rakesh C Arora; Judson B Williams; Rawn Salenger; Subhasis Chatterjee; Kevin W Lobdell; Marjan Jahangiri; Daniel T Engelman Journal: J Cardiothorac Vasc Anesth Date: 2020-08-10 Impact factor: 2.628
Authors: Kimberley J Haines; Elizabeth Hibbert; Nina Leggett; Leanne M Boehm; Tarli Hall; Rita N Bakhru; Anthony J Bastin; Brad W Butcher; Tammy L Eaton; Wendy Harris; Aluko A Hope; James Jackson; Annie Johnson; Janet A Kloos; Karen A Korzick; Pamela Mactavish; Joel Meyer; Ashley Montgomery-Yates; Tara Quasim; Andrew Slack; Dorothy Wade; Mary Still; Giora Netzer; Ramona O Hopkins; Theodore J Iwashyna; Mark E Mikkelsen; Joanne McPeake; Carla M Sevin Journal: Crit Care Med Date: 2021-11-01 Impact factor: 9.296