Victoria Kershaw1,2, Aethele Khunda3, Carol McCormick3, Paul Ballard3. 1. South Tees Hospitals NHS Foundation Trust, Marton Road, Middlesbrough, TS4 3BW, UK. victoria.kershaw@nhs.net. 2. James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK. victoria.kershaw@nhs.net. 3. South Tees Hospitals NHS Foundation Trust, Marton Road, Middlesbrough, TS4 3BW, UK.
Abstract
INTRODUCTION: Percutaneous tibial nerve stimulation (PTNS) is now an established treatment of pelvic floor dysfunction such as overactive bladder, faecal incontinence or voiding dysfunction. Prevalence of female sexual dysfunction is high in this group. We aim to examine the effect of PTNS on sexual function in this patient group by systematically reviewing the literature and pooling the data in a meta-analysis. METHODS: The literature search was conducted using the MEDLINE, Embase and CINAHL databases. Initial results yielded 74 citations. From these, nine articles met our inclusion criteria. Two articles were doubly reported, leaving seven studies in the systematic review. Only four studies reported sufficient information to be included in our meta-analysis. RESULTS: Three studies were randomised controlled trials, and five were before-after studies. The number of participants in each study ranged from 11 to 220. Four out of seven studies reported a positive effect of PTNS on sexual function. In the meta-analysis of four studies there was a significant improvement in general sexual function with PTNS (p = 0.04, SMD -0.41, CI[-0.79, -0.03], I2 = 0%). In a subgroup analysis of the bowel domain of sexual function, there was a significant improvement with PTNS (p = 0.03, MD 17.7, CI [1.92, 33.47], I2 = 0%). CONCLUSION: We report a systematic review on the effect of PTNS on sexual function. Although the studies are of small size, the results are promising in terms of a positive effect of PTNS on sexual function, and we recommend further research in this area.
INTRODUCTION: Percutaneous tibial nerve stimulation (PTNS) is now an established treatment of pelvic floor dysfunction such as overactive bladder, faecal incontinence or voiding dysfunction. Prevalence of female sexual dysfunction is high in this group. We aim to examine the effect of PTNS on sexual function in this patient group by systematically reviewing the literature and pooling the data in a meta-analysis. METHODS: The literature search was conducted using the MEDLINE, Embase and CINAHL databases. Initial results yielded 74 citations. From these, nine articles met our inclusion criteria. Two articles were doubly reported, leaving seven studies in the systematic review. Only four studies reported sufficient information to be included in our meta-analysis. RESULTS: Three studies were randomised controlled trials, and five were before-after studies. The number of participants in each study ranged from 11 to 220. Four out of seven studies reported a positive effect of PTNS on sexual function. In the meta-analysis of four studies there was a significant improvement in general sexual function with PTNS (p = 0.04, SMD -0.41, CI[-0.79, -0.03], I2 = 0%). In a subgroup analysis of the bowel domain of sexual function, there was a significant improvement with PTNS (p = 0.03, MD 17.7, CI [1.92, 33.47], I2 = 0%). CONCLUSION: We report a systematic review on the effect of PTNS on sexual function. Although the studies are of small size, the results are promising in terms of a positive effect of PTNS on sexual function, and we recommend further research in this area.
Entities:
Keywords:
PTNS; Percutaneous tibial nerve stimulation; Sex
Authors: Karin S Coyne; Mary Kay Margolis; Zhanna Jumadilova; Tamara Bavendam; Elizabeth Mueller; Rebecca Rogers Journal: J Sex Med Date: 2007-05 Impact factor: 3.802
Authors: R G Rogers; T H Rockwood; M L Constantine; R Thakar; D N Kammerer-Doak; R N Pauls; M Parekh; B Ridgeway; S Jha; J Pitkin; F Reid; S E Sutherland; E S Lukacz; C Domoney; P Sand; G W Davila; M E Espuna Pons Journal: Int Urogynecol J Date: 2013-04-30 Impact factor: 2.894
Authors: María Del-Carmen Díaz-Ruiz; Rita-Pilar Romero-Galisteo; Beatriz Arranz-Martín; Rocío Palomo-Carrión; Sara Ando-Lafuente; Cristina Lirio-Romero Journal: Int J Environ Res Public Health Date: 2022-01-28 Impact factor: 3.390