| Literature DB >> 31264495 |
Maciej Łukawski1, Paulina Dałek1,2, Tomasz Borowik2, Aleksander Foryś3, Marek Langner1,2, Wojciech Witkiewicz4, Magdalena Przybyło1,2.
Abstract
Vitamin C is the exogenous compound necessary for a variety of metabolic processes; therefore, the efficient delivery is critical for the maintenance of body homeostasis. Vitamin C pharmacokinetics and low quantities in processed foodstuff, necessitates its continuous supplementation. In the paper, we present the new liposomal formulation of vitamin C free of harmful organic solvents. The formulation was quantitatively characterized with respect to its chemically composition and nano-structuring. The vitamin C accessibility to cells from the formulation was evaluated using evidence derived from experiments performed on cell cultures. Finally, the enhanced bioavailability of vitamin C from the formulation was demonstrated in the medical experiment.Entities:
Keywords: Liposome; bioavailability; efficacy; stability; vitamin C
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Year: 2019 PMID: 31264495 DOI: 10.1080/08982104.2019.1630642
Source DB: PubMed Journal: J Liposome Res ISSN: 0898-2104 Impact factor: 3.648