Literature DB >> 31219892

Successful Migration from Radioactive Irradiators to X-ray Irradiators in One of the Largest Medical Centers in the US.

Jacob Kamen1, Wen-Ya Hsu1, Brandon Boswell1, Colin Hill2.   

Abstract

This paper summarizes about 9 years of effort by Mount Sinai to successfully migrate completely from radioactive irradiators to x-ray irradiators without compromising patient care or research studies. All the effort by Mount Sinai to permanently remove the risk of malicious use of radioactive materials as Radiological Dispersal Device or dirty bomb is reviewed. Due to the unique characteristics of the cesium chloride (CsCl) used in irradiators, it is especially susceptible to be used as a dirty bombs. Mount Sinai originally had four of such irradiators. To reduce and eventually remove the risk of malicious use of radioactive materials, Mount Sinai in New York City has taken several steps. One of such measures was to harden the radioactive irradiators to make the radioactive materials harder to be stolen for malicious purposes. By increasing the delay time, the local law enforcement agency (LLEA) will have more time to stop the intruder. Another measure taken was to implement enhanced security in facilities having radioactive materials. We collaborated with the National Nuclear Security Administration and used state-of-the-art security equipment such as Biometric Access Control and 24/7 video monitoring. In addition, a remote monitoring system with alarms was installed and connected to LLEA for constant monitoring and possible intervention, if necessary, in a timely manner. The other measure taken was to limit the number of people who have access to such radioactive materials. We adopted a single person operator method and reduced the number of people having access from 145 people to only a few people. The adoption of such measures has reduced the risk significantly; however, the best way to remove the permanent risk of these radioactive materials that may be used for a dirty bomb is to use alternative technology to replace these high-activity radioactive sources. In 2013, Mount Sinai purchased its first x-ray irradiator to investigate the feasibility of using x-ray irradiators instead of cesium irradiators for research purposes for cells and small mice. The results from comparison studies were promising, which led to the decision of permanent migration of all cesium irradiators to x-ray irradiators. As of January 2018, Mount Sinai successfully disposed all its Cs irradiators. At this time, Mount Sinai, as one of the largest health care institutions in NY with about 50,000 employees, has migrated completely to alternative technology and removed the risk of malicious use of radioactive materials permanently.

Entities:  

Year:  2019        PMID: 31219892     DOI: 10.1097/HP.0000000000001095

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  3 in total

1.  Modeling Cell Survival Fraction and Other Dose-Response Relationships for Immunodeficient C.B-17 SCID Mice Exposed to 320-kV X Rays.

Authors:  Bobby R Scott; Yong Lin; Bryanna Saxton; Wenshu Chen; Charles A Potter; Steven A Belinsky
Journal:  Dose Response       Date:  2021-05-31       Impact factor: 2.658

2.  Generation of bone marrow chimeras using X-ray irradiation: comparison to cesium irradiation and use in immunotherapy.

Authors:  Jason Eng; Jessica Orf; Kristy Perez; Deepali Sawant; Jason DeVoss
Journal:  J Biol Methods       Date:  2020-02-17

3.  Comparable human reconstitution following Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice.

Authors:  Anna Halling Folkmar Andersen; Stine Sofie Frank Nielsen; Rikke Olesen; Jakob Le Fèvre Harslund; Ole Schmeltz Søgaard; Lars Østergaard; Paul W Denton; Martin Tolstrup
Journal:  PLoS One       Date:  2020-10-29       Impact factor: 3.240

  3 in total

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