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Literature DB >> 31217610

CRISPR babies: when will the world be ready?

Heidi Ledford.

Abstract

Entities: Chemical

Keywords: Ethics; Genetics; Genomics; Law

Mesh：

Year: 2019 PMID： 31217610 DOI： 10.1038/d41586-019-01906-z

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 69.504

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10 in total

1. RNA-guided DNA insertion with CRISPR-associated transposases.

Authors: Jonathan Strecker; Alim Ladha; Zachary Gardner; Jonathan L Schmid-Burgk; Kira S Makarova; Eugene V Koonin; Feng Zhang
Journal: Science Date: 2019-06-06 Impact factor: 47.728

2. Adopt a moratorium on heritable genome editing.

Authors: Eric S Lander; Françoise Baylis; Feng Zhang; Emmanuelle Charpentier; Paul Berg; Catherine Bourgain; Bärbel Friedrich; J Keith Joung; Jinsong Li; David Liu; Luigi Naldini; Jing-Bao Nie; Renzong Qiu; Bettina Schoene-Seifert; Feng Shao; Sharon Terry; Wensheng Wei; Ernst-Ludwig Winnacker
Journal: Nature Date: 2019-03 Impact factor: 49.962

3. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice.

Authors: Shuai Jin; Yuan Zong; Qiang Gao; Zixu Zhu; Yanpeng Wang; Peng Qin; Chengzhi Liang; Daowen Wang; Jin-Long Qiu; Feng Zhang; Caixia Gao
Journal: Science Date: 2019-02-28 Impact factor: 47.728

4. Correction of a pathogenic gene mutation in human embryos.

Authors: Hong Ma; Nuria Marti-Gutierrez; Sang-Wook Park; Jun Wu; Yeonmi Lee; Keiichiro Suzuki; Amy Koski; Dongmei Ji; Tomonari Hayama; Riffat Ahmed; Hayley Darby; Crystal Van Dyken; Ying Li; Eunju Kang; A-Reum Park; Daesik Kim; Sang-Tae Kim; Jianhui Gong; Ying Gu; Xun Xu; David Battaglia; Sacha A Krieg; David M Lee; Diana H Wu; Don P Wolf; Stephen B Heitner; Juan Carlos Izpisua Belmonte; Paula Amato; Jin-Soo Kim; Sanjiv Kaul; Shoukhrat Mitalipov
Journal: Nature Date: 2017-08-02 Impact factor: 49.962

5. Inter-homologue repair in fertilized human eggs?

Authors: Dieter Egli; Michael V Zuccaro; Michael Kosicki; George M Church; Allan Bradley; Maria Jasin
Journal: Nature Date: 2018-08-08 Impact factor: 49.962

6. Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system.

Authors: Tyler S Halpin-Healy; Sanne E Klompe; Samuel H Sternberg; Israel S Fernández
Journal: Nature Date: 2019-12-18 Impact factor: 49.962

7. Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos.

Authors: Erwei Zuo; Yidi Sun; Wu Wei; Tanglong Yuan; Wenqin Ying; Hao Sun; Liyun Yuan; Lars M Steinmetz; Yixue Li; Hui Yang
Journal: Science Date: 2019-02-28 Impact factor: 47.728

8. CCR5-∆32 is deleterious in the homozygous state in humans.

Authors: Xinzhu Wei; Rasmus Nielsen
Journal: Nat Med Date: 2019-06-03 Impact factor: 53.440

9. High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Authors: Benjamin P Kleinstiver; Vikram Pattanayak; Michelle S Prew; Shengdar Q Tsai; Nhu T Nguyen; Zongli Zheng; J Keith Joung
Journal: Nature Date: 2016-01-06 Impact factor: 49.962

10. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Authors: Alexis C Komor; Yongjoo B Kim; Michael S Packer; John A Zuris; David R Liu
Journal: Nature Date: 2016-04-20 Impact factor: 49.962

10 in total

7 in total

Review 1. Humanized mouse models of genetic immune disorders and hematological malignancies.

Authors: Rajeev K Tyagi; Jing Li; Justin Jacobse; Scott B Snapper; Dror S Shouval; Jeremy A Goettel
Journal: Biochem Pharmacol Date: 2019-10-18 Impact factor: 5.858

Review 2. CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues.

Authors: Roberto Piergentili; Alessandro Del Rio; Fabrizio Signore; Federica Umani Ronchi; Enrico Marinelli; Simona Zaami
Journal: Cells Date: 2021-04-21 Impact factor: 7.666

Review 3. Genetics Matters: Voyaging from the Past into the Future of Humanity and Sustainability.

Authors: Acga Cheng; Jennifer Ann Harikrishna; Charles S Redwood; Lei Cheng Lit; Swapan K Nath; Kek Heng Chua
Journal: Int J Mol Sci Date: 2022-04-02 Impact factor: 6.208

Review 4. Human germline genome editing.

Authors: Rebecca A Lea; Kathy K Niakan
Journal: Nat Cell Biol Date: 2019-12-04 Impact factor: 28.824