| Literature DB >> 31208694 |
Tobias Ackermann1, Saverio Tardito2.
Abstract
Historic cell culture media were designed to ensure continuous cancer cell proliferation in vitro. However, their composition does not recapitulate the nutritional environment of the tumor. Recent studies show that novel media formulations alleviate the nonphysiological constraints imposed by historic media, and lead to cell culture results that are more relevant to tumor metabolism.Entities:
Keywords: cancer metabolism; cancer models; physiological medium
Mesh:
Substances:
Year: 2019 PMID: 31208694 PMCID: PMC6557711 DOI: 10.1016/j.trecan.2019.05.004
Source DB: PubMed Journal: Trends Cancer ISSN: 2405-8025